Lots of exciting events in the Li Lab! First, congratulations to Dr. Chris Ritchie on an outstanding thesis defense!! Chris is a western blot whiz and a cycling connoisseur. We are super proud!

Congratulations to 2nd year Chemistry student Alby Joseph (he/him) for passing his qualifying exam!

Celebrated lab achievements over mini golf! Labs that putt-putt together, stay together! ⛳️

Don't miss the seminar by prof. Lingyin Li from Lingyin Li Lab Stanford Biochemistry this Wednesday at 11am EST: "Extracellular cGAMP signaling in health & Disease" You can tune in on zoom: nyulangone.zoom.us/j/95442008054?… +Info: ictiseminars.com Please share!

🚨New preprint alert 🚨 Work by Dr. Chris Ritchie shows PELI2’s role in regulating STING activation! biorxiv.org/content/10.110…

Congratulations Dr. Rachel Mardjuki!! Rachel is a protein purification pro and a singing superstar. So proud of you Rachel Mardjuki!

🚨New preprint alert 🚨 Check out this work led by Songnan Wang | 王松南 on ENPP1 and it’s role as an innate immune checkpoint in breast cancer! biorxiv.org/content/10.110…

Follow (the real) Lingyin and check out new preprint! In short, superstars Rebecca Chan and X Cao dig deep into what it takes to activate STING and the best therapeutic strategy to inhibit STING signaling!

Li lab rising star Alby Joseph (he/him) (Jacob Jingleheimer Schmidt) kicks off the Stanford Chemistry graduate students Third Year Seminar!

We are so proud of MD-PhD student and food enthusiast @SongnanWang for her exciting new work characterizing ENPP1 as an innate immune checkpoint for breast cancer! Biggest congratulations to Songnan and coauthors Alby Joseph (he/him) Valentino Sudaryo

I'm happy to share ColabFold-Pipeline-Toolkit, an easy recipe book put together to help streamline the use of ColabFold for newcomers without a computing background who want to perform high-throughput screens with ColabFold BATCH. 🧵 github.com/andyposbe/Cola…

How do phages/MGEs overcome bacterial defenses? Delve into our Nature Reviews Genetics review on 𝗶𝗻𝗵𝗶𝗯𝗶𝘁𝗼𝗿𝘀 𝗼𝗳 𝗯𝗮𝗰𝘁𝗲𝗿𝗶𝗮𝗹 𝗶𝗺𝗺𝘂𝗻𝗶𝘁𝘆!🛡️ We discuss discovery methods, classify mechanisms, & examine their biotech potential!🧬 nature.com/articles/s4157… 1/11

Read this amazing perspective from our fearless leader looking back at the work that started it all and forward to all that's to come in cancer innate immunotherapy!!

Check out the lab's discovery of the newest player in cancer immunotherapy! Lead author and protein biochemistry expert Rachel Mardjuki is also on the job market for those in search of all-around brilliance!

Congratulations Dr. Chris Ritchie on new work defining PELI2 as a negative regulator of STING, now published Molecular Cell! Read the paper here: cell.com/molecular-cell…

Such an honour and pleasure to host Lingyin Li Lab in Leiden last Friday on the occasion of the 10th ICI symposium of Institute for Chemical Immunology. Fabulous talk on STING signalling and oligomerisation, PTMs, ENPP1 and ENPP3!

It’s not often we catch all of our Core Investigators in one place, standing still, but we did it! Welcome Felix Horns - Patrick Hsu, Silvana Konermann, Lingyin Li, PhD, LukeGilbert, Hani Goodarzi and Arc Science Fellows Uche Medoh and Jingtian Zhou are glad you're here.

Today in @nature, we discover a new enzyme in mammalian taurine metabolism- and uncover a chemical connection between diet, genetics, and body weight. Congrats Wei Wei (魏伟) Sarafan ChEM-H Stanford Pathology Michael Fischbach Cholsoon Jang SvenssonLab Lingyin Li Lab nature.com/articles/s4158…

Congratulations to Zhijian "James" Chen for winning the #Lasker2024 for his foundational discovery of cGAS! laskerfoundation.org/winners/cgas-e…

🚨New cGAMP transporter just dropped🚨 Check out the latest preprint from the lab, led by grad student Valentino implicating SLC7A1 as the dominant cGAMP transporter in T cells biorxiv.org/content/10.110…