“Chimeric models of breast cancer brain metastases and demyelination” — such an interesting and innovative approach! Harnessing human iPSC-microglia for CNS-wide delivery of disease-modifying proteins: Cell Stem Cell cell.com/cell-stem-cell…

Online now: Chimeric brain models: Unlocking insights into human neural development, aging, diseases, and cell therapies dlvr.it/TKQfYD

p16-expressing microglia and endothelial cells promote tauopathy and neurovascular abnormalities in PS19 mice: Neuron cell.com/neuron/fulltex…

Senescence-resistant human mesenchymal progenitor cells counter aging in primates: Cell cell.com/cell/fulltext/…

🧩Today is #AutisticPrideDay! Up to 18% of people w/#DownSyndrome also have #Autism. At GLOBAL we're committed to supporting & celebrating people w/the dual diagnosis like our brilliant #GLOBALAmbassador, Micah Quinones! Watch his AMAZING story here: bit.ly/3HLHEBu

The R136S mutation in the APOE3 gene confers resilience against tau pathology via inhibition of the cGAS-STING-IFN pathway: Immunity cell.com/immunity/fullt…

TET2-mutant myeloid cells mitigate Alzheimer’s disease progression via CNS infiltration and enhanced phagocytosis in mice: Cell Stem Cell cell.com/cell-stem-cell…

The Somatic Mosaicism across Human Tissues Network | Nature nature.com/articles/s4158…

Microglia replacement halts the progression of microgliopathy in mice and humans | Science Magazine science.org/doi/10.1126/sc…

Rare post-mortem brains of so-called “resilient” subjects are defined as having ample amyloid plaques and tangles but no dementia at death. The reason, every time? Absence of neuroinflammation! Amyloid causes tangles, which cause neuroinflammation, without which, no Alzheimer’s!