So elegant. Is there any evidence to the contrary? because I’d really like to believe this is a better explanation for HPC than the zoo of cells and remapping phenomena

Modern neuroscientists routinely record the complex, goal-oriented, and time-varying activity of thousands of neurons. Can we find representations of neural activity that 1) are human-interpretable and 2) enable the generation of neural activity for unrecorded behavioral

Our new study is out today in the New England Journal of Medicine! We demonstrate a speech neuroprosthesis that decodes the attempted speech of a man with ALS into text with 97.5% accuracy, enabling him to communicate with his family, friends, and colleagues in his own home. 1/9

Today, we're shipping a series of features that move uv beyond a pip alternative, and into an end-to-end solution for managing Python projects, command-line tools, single-file scripts, and even Python itself. A single, unified tool. Like Cargo, for Python. It's very fast.

AI hardware systems such as NVIDIA's GPUs are a true marvel of technology. Extremely complex structure that also harnesses enormous amounts of energy. That is because modern AI algorithms involve multiple functions, and GPUs implement those over multiple physical components.

I'm stuck in some kind of weird nerd Groundhog Day scenario where I Google a new thing and find out it's all computations and always has been. (yes the meme is in there, obviously) rdgao.com/blog/2024/08/1…

DPAD is finally out in Nature Neuroscience! 🎉 I actually started this work during the last year of my PhD back in 2020 (!) & we posted the preprint 3 years ago!!! Some things really do take time... Huge thanks to Maryam Shanechi for her unwavering support throughout this journey! 🙌

Out now! Byron Yu, ShenghaoWu, Matt Smith, Brent Doiron, Chengcheng Huang et al. present a procedure to customize spiking network models that reproduce the population-wide covariability of large-scale neuronal recordings. nature.com/articles/s4358… ➡️rdcu.be/dT5i9

How can we train biophysical neuron models on data or tasks? We built Jaxley, a differentiable, GPU-based biophysics simulator, which makes this possible even when models have thousands of parameters! Led by Michael Deistler, collab with @CellTypist @ppjgoncalves biorxiv.org/content/10.110…

Despite what downers may say, LLMs often save me quite a bit of time

1/4 Check out our preprint, “Non-invasive brain-machine interface control with artificial intelligence copilots.” (biorxiv.org/content/10.110…). We demonstrate a paralyzed participant has non-invasive neural control of a cursor and a robotic arm (video: youtube.com/watch?v=SFQDkM…).

Got this email from one of my undergrad mentees. Feeling my blood pressure rise vicariously.

At NeurIPS and care about dynamical systems models for neuroscience? Come check out Yenho Chen presenting his poster on "Probabilistic Decomposed Linear Dynamical Systems for Robust Discovery of Latent Neural Dynamics" on Wed at 4:30pm (#3910).

New in NeurIPS Conference, we develop PGLDM, an analytical subspace identification method to jointly model two generalized-linear time-series & dissociate their shared vs private dynamics. #NeurIPS2024 Poster Sess 5 East #3808, Fri Dec 13 11am 👏Lucine Oganesian Omid Sani Paper, Code &🧵⬇️

Can we efficiently learn models of collective dynamics in multimodal discrete-continuous time-series, e.g. spike-LFP? We develop a new multimodal subspace identification method to do so & enable causal multimodal decoding! 👏Parima Ahmadipour Omid Sani J Neural Eng paper, code,🧵⬇️

Let's not though

Say `Hello` 👋 to FastHTML and MonsterUI Modern Python🐍 web development 👨‍💻 made easy! Thanks Jeremy Howard and Isaac Flath! drewecherd.com/post/hello-fas…

Trying out marimo. Pretty slick modern reactive notebooks---just what I wanted from Julia's Pluto.jl, but with Python, and can browser-only via WASM

Very interesting: e11.bio/news/roadmap

I'm a libertarian, so I don't necessarily support all government spending, but the public should be at the very least aware of the benefits of science: publicusaresearchbenefits.com