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Lustgarten-funded science making headlines! "Leveraging the immune system by combining KRAS inhibitors w/ immunotherapy was able to bring about the full effects of these drugs & provide the best possible survival."-Anirban Maitra MD Anderson Cancer Center Break Through Cancer lfdn.org/3RoPCU0

Main credit goes to the hard work of Krishnan & Kate McAndrews from Kalluri Lab. You can find them both at #AACRPan23 in Boston. MD Anderson Cancer Center Lustgarten Foundation Break Through Cancer

Researchers at MD Anderson Cancer Center found a role for KRAS mutations in pancreatic cancer and created a novel therapeutic approach combining a KRAS G12D inhibitor with immune checkpoint inhibitors for KRAS G12D-mutant #PancreaticCancer. ow.ly/4bP750POkUT

From a combination therapy for KRAS-mutated pancreatic cancer to potential targets for improving stomach cancer treatment to recent highlights from #ESMO23, learn about our latest research: brnw.ch/21wDSKI Dr. Ron DePinho #PancreaticCancer #GastricCancer #EndCancer

"Immunotherapies alone have made little impact against pancreatic cancer, but new research suggests combining them with KRAS-G12D inhibition may hold the key to durable responses." 2 out of the 3 papers referenced are from our group (and collaborators)! nature.com/articles/d4247…

New Science Magazine publication from Kalluri Lab MD Anderson Cancer Center Type I conventional dendritic cells facilitate immunotherapy in #PancreaticCancer science.org/doi/10.1126/sc… How is the tumor immune microenvironment of pancreatic cancer associated with pancreatitis (ptPDAC)

Type I conventional dendritic cells facilitate immunotherapy in pancreatic cancer. Kalluri Lab MD Anderson Cancer Center 👏👏👏 sciencemagazinedigital.org/sciencemagazin…

In Immunity, Raghu Kalluri discusses the role of extracellular vesicles (EVs) in immune response and immunity. Might EVs be the original primordial units preceding creation of the first cell? cell.com/immunity/fullt…

A huge thank you to my mentor Dr.Kalluri Raghu Kalluri and Dr.LeBleu Val. I cannot make it without the support of Kalluri lab Kalluri Lab.

I am happy to share the latest paper from Goswami_Lab in Nature Immunology. We showed the integration of metabolic & epigenetic pathways regulating CD8 T cell mediated anti tumor immunity via histone lactylation. ⁦Deblina Raychaudhuri⁩⁦@RaiPratishtha⁩⁦MD Anderson Cancer Center⁩

Many thanks to David DeNardo WUSM for their spotlight article on our cDC1 vaccine. 👉cell.com/trends/pharmac… ICYMI: our work in Science Magazine by Krishnan and colleagues: cDC1 vaccine facilitates curative immunotherapy in PDAC. 👉 science.org/doi/10.1126/sc…

KRASG12D-Specific Targeting with Engineered Exosomes Reprograms the Immune Microenvironment to Enable Efficacy of Immune Checkpoint Therapy in PDAC Patients medrxiv.org/content/10.110… First in human personalized medicine with exosomes! Kalluri Lab Anirban Maitra

📣Coming Soon: Extracellular Vesicles and Exosomes Biology Core Facility (EVcore) A first of its kind facility to support your EV research needs including isolation, characterization, imaging, engineering and more. Grateful to CPRIT for supporting this resource. Stay