The Confinement Mechanobiology Lab at MBI's latest paper is out in PNASNews! Fantastic work by LI Yixuan to build a tool to rapidly and accurately measure nuclear volume and surface area in #confinement. Thread below: pnas.org/doi/10.1073/pn…

Check out our latest work on fluid viscosity and hMSC fate in Science Advances led by AliceAmitrano and Qinling Y . Many thanks to Konstantopoulos Lab members BHAWANA AGARWAL and Anindya Sen, our collaborators Jude Phillip and Dr. Gu and their mentees. science.org/doi/10.1126/sc…

Congrats to the Konstantopoulos lab (Konstantopoulos Lab) at Johns Hopkins University on their new Science Advances study! 🎉 They show that extracellular fluid viscosity regulates human #MesenchymalStemCell lineage and function. Read the paper: bit.ly/4h1bdLv

Our new paper defining the role of H3K36 methylation in regulating cell fate and plasticity is available online: rdcu.be/d5AEc Thanks to Alison Pashos, PhD and our entire team for their tireless work and to the editors at Nature Cell Biology for the opportunity!

The Confinement Mechanobiology Lab at MBI is hiring! If you are interested in doing a #postdoc at the Mechanobiology Institute in science-friendly #Singapore, please reach out! We have a multi-year fully funded position designed to help you meet your career goals in the rapidly growing field of cellular #confinement!

Excited to share our latest review led by AliceAmitrano & Debanik Choudhury, PhD! We dive into the mechanisms of confined cell migration, exploring how ion channels, cell cytoskeleton, and fluidic & solid cues drive motility & metabolic reprogramming. Read more: doi.org/10.1016/j.ceb.…

🎉🥳 Congratulations to recent grad Nathaniel Skillin for his new paper assessing foreign body response and in vivo performance of implanted LCE nanocomposites! Nat found that these materials still actuate to >10% strains with transcutaneous NIR light after fibrous capsule formation.

Delighted to share our latest paper, led by Alex Khang, out now in Nature Communications. Alex developed an analysis pipeline that uses mathematical descriptors of cell morphology to assign (myo)fibroblast phenotypes, avoiding the laborious and subjective process of manual image grading!

🎆🎇 Congrats to F. Max Yavitt for his new paper, "Engineered epithelial curvature controls Paneth cell localization in intestinal organoids," out now in Cell Biomaterials. Max explored how local matrix curvature influences differentiation of confined intestinal organoids — link below!

Very excited to see our work published in Adv. Biology, using tunable hydrogels to investigate the role of PTEN in AVS progression! Huge thanks to Dilara Batan and to the Anseth Group for their support! Stay tuned!

Huge congrats to my first-year PhD student, Josiah Power Josiah Power on receiving an U.S. National Science Foundation GRFP! At just 19 and with a double-major in ChemBE & Biochem, he took 5 doctoral-level courses last fall (vs. the usual 3) and aced them all. Incredible talent and drive- well deserved!

Fresh science! Check out our Confinement Mechanobiology Lab at MBI’s new paper on how confined migration can drive stem cell differentiation in Advanced Portfolio News. Let’s do a thread! advanced.onlinelibrary.wiley.com/doi/full/10.10… (1/n)

Interested in a #postdoc on nuclear #mechanobiology? We have a fully funded position in the Confinement Mechanobiology Lab at MBI designed to help you meet your career goals while researching the rapidly growing field of cellular #confinement. Please get in touch for more info!

Thrilled that our newest work led by Avery, Dr. Wisniewski, and Panagiotis Mistriotis is out today in Nature Materials! We show how the cytokinesis proteins Anillin and Ect2 drive RhoA/ROCK/myosin-mediated invasion in confining spaces in vitro and in vivo. doi.org/10.1038/s41563….

Interested in a #postdoc on cardiac #mechanobiology? Our lab has a fully funded position via our recently awarded HFSP grant to study the biophysical processes that build insect hearts🪲🪰🫀 Come join us Mechanobiology Institute for some cool evo-devo-mechanobio work! 👇 mbi.nus.edu.sg/jobs/seeking-p…

i am very pleased to share that my PhD thesis defense will be on 7/29 (Tuesday) at 10AM MDT. let me know if you'd like the Zoom link! i will be returning to medical school in September and may even finish school before i turn 40 (no promises).

Pleased to share our latest collaborative work with the Devreotes Lab - Johns Hopkins University in PNASNews. Using optogenetics, we show that both insufficient and excessive Ras activity impair cell motility, underscoring the need for optimal Ras signaling and cortical tension. doi.org/10.1073/pnas.2…

We have many things to share that we are celebrating: we had two fantastic summer undergrads, Kaeden and Aahana, who leave today 🥹 Grad students Mark and Bruce both defended their PhD theses!! 🥳 Plus, grad student Nolan received an NSF-GRFP award 👏Congratulations to all! 🎊 🎉

My final paper from graduate school is out now! Another fantastic collaboration between R+PM Group and Anseth Group, we show that mechanical anisotropy of liquid crystals can be retained in hydrogels through clever chemistry and biofabrication approaches! doi.org/10.1002/adfm.2…

🥳 We’re delighted to share our latest work in Science Advances with BurdickLab, developing DLP-printable hydrogel formulations that contain initiator-free photochemistries for functionalization, stiffening, and softening. Congrats to all involved! science.org/doi/10.1126/sc…