JOB OPPORTUNITY! 🧠🔬🧪 9 labs at Salk have joined forces to understand how aging contributes to Alzheimer’s + other age-associated conditions. The team is seeking talented postdoctoral fellows who can work across disciplines. Please RT and share! recruiting2.ultipro.com/SAL1013SIBS/Jo…

Excited to share this spotlight on Molecular Cell with Liuh-Yow Chen, highlighting a telomere-dependent tumor suppressive mechanism via mitochondria that acts during replicative crisis from Joe Nassour The Karlseder Lab authors.elsevier.com/c/1gtA73vVUPNx…

Great job to the Arnoult lab for their recent publication in Molecular Cell! Their study highlights the critical role that APE2 nuclease plays in Pol Theta-mediated MMEJ. Congratulations!🥳

Some tumors repair their DNA via microhomology-mediated end joining (MMEJ), rather than with homologous recombination (HR). Scientists find that MMEJ relies on the APE2 nuclease, revealing a chink in the armor of HR-deficient cancers. @ArnoultLab ow.ly/jv8y50NHfLT

Postdoc positions are available in our group at the University of Colorado @cuanschutz to study the crosstalk between telomeres and mitochondria in innate immunity. See details below, and feel free to DM or email me for further info!

Our lab website is now live! Explore opportunities and learn about our research on telomere-mitochondria-innate immunity crosstalk at nassourlab.com

This is a fantastic chance for anyone interested in the interplay between mitochondria and innate immune responses!

Our latest review 'Telomeres as hotspots for innate immunity and inflammation' is now live DNA Repair! Here, we describe how dysfunctional telomeres activate innate immune pathways and fuel inflammaging. Check it out Sara Przetocka The Karlseder Lab doi.org/10.1016/j.dnar…

Don't miss out on this event!

Learn how The Karlseder Lab & team used nanopore technology to investigate telomere shortening during cellular aging. Check out how they also studied how alternative lengthening of telomeres and telomerase impact iPSCs and cancer cells. Read more: bit.ly/46AgRPb

In parallel to us, the Artandi lab has also established telomere long-read sequencing. Check out their preprint:

Please also check out complementary work on telomere sequencing from the Artandi lab (Steven Artandi, MD, PhD) published in the same issue Nature Communications nature.com/articles/s4146…. Congrats to Santiago (santiago) and all collaborators!

Introducing Telo-seq: a new tool from @SalkInstitute and Oxford @Nanopore that will revolutionize the study of aging and cancer. Scientists can now measure and sequence telomeres on individual chromosomes with unprecedented resolution. #SalkHealthyAging salk.edu/news-release/u…