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New preprint: Mind how you sweat! Pleiotropic brain enhancer shapes how sweat glands evolve. Awesome work from Daniel Aldea @dingwallaby Blerina Kokalari with help from Cotsarelis lab and Yuji Atsuta! Penn Genetics @PennSbdrc biorxiv.org/content/10.110…

Excited to share the preprint of my latest work. Wonder how oncogenic Kras disrupts tissue architecture? We find it does so through converting pulsatile into sustained ERK activation! Thank my mentor valentina greco, collaborator Sergi Regot and other authors!

Mind how you sweat! Enhancer pleiotropy shapes how an adaptive trait evolved. Even made a model! Our new paper is out in PLoS Genetics! journals.plos.org/plosgenetics/a…

New paper is out! The "Ectodysplasin" road less traveled...and the importance of genetic background! Ectodysplasin signaling via Xedar is required for mammary gland morpho... sciencedirect.com/science/articl… Congrats Abby Wark Daniel Aldea #Reiko Tomizawa @PennSbdrc Penn Genetics

A transient dermal niche and dual epidermal programs underlie sweat gland development biorxiv.org/cgi/content/sh… #bioRxiv

Our "coolest" new preprint is up! Classic genetics + single transcriptomics = a novel niche and a recipe for identity of the eccrine gland...humans' indispensable thermoregulatory organ. Congrats @dingwallaby and all the team! biorxiv.org/content/10.110…

We are recruiting a post-doc to work in regenerative and evolutionary biology of human skin! jobrxiv.org/job/university…

We also had Prizes! Denay Richards (Devenport Lab, Princeton University) won Best Short Talk. Best Poster Prizes were awarded to Dr. Dingwall (kamberovlab, UPenn) and Dr. Wang (Rendl Lab, Icahn School of Medicine at Mount Sinai). Congratulations!

"How the skin got its sweat". Our new paper just went live. Sweat gland development requires an eccrine dermal niche and couples t... sciencedirect.com/science/articl…

New ppr in Developmental Cell in which we flip skin fate from sweat gland to hair follicle to uncover the instructive sweat gland niche and the developmental signature of sweat gland identity. Congrats @dingwallaby and the team! @PennSbdrc Penn Genetics Institute for Regenerative Medicine doi.org/10.1016/j.devc…