Kai Ehrenbolger
@kai_ehrenbolger
ID: 1002369974080589824
01-06-2018 02:03:19
42 Tweet
101 Followers
188 Following
Our paper on #poliovirus assembly by #cryoET is out! Congratulations to Selma selma dahmane, Adeline Kerviel, @, Precipitated_protein, Björn Ahlman, Michael Lazarou, Nihal Altan-Bonnet. #teamtomo #cryoEM. A short🧵on the main findings (1/7). nature.com/articles/s4146…
New publication from the Carlson Laboratory: How cryo-EM revealed the secrets of enterovirus replication: bit.ly/3MC5nSY Congrats to selma dahmane, first author, and Lars-Anders Carlson, lead PI, MIMS Investigator to this amazing discovery! 🎉 Nordic EMBL P'ship
Released today EMDB - EMPIAR @EBI & Protein Data Bank, & published Nature Communications, the magnificent 2.8 Å #SingleParticle #CryoEM structure of the Vairimorpha necatrix 20S #Proteasome from #Spores, bound with PI31-like #Inhibitor #Peptides at the 6 active sites within the cavity. #EMDB 1/2
Study by Nathan Jespersen, Kai Ehrenbolger et al. from Umeå Centre for Microbial Research & CAES. Data EMDB - EMPIAR @EBI & Protein Data Bank #EMDB: emdb-empiar.org/EMD-15365 #PDBe: pdbe.org/8adn Related: emdb-empiar.org/EMD-15366 Related: emdb-empiar.org/EMD-15367 Paper: doi.org/10.1038/s41467… 2/2
Proud to see our DMS paper out in Nature Chemical Biology after going through a productive review process🥳EfrCD's drug efflux activity profile determined for >1400 single variants. Identified single mutations that convert the exporter into a drug-specific ABC importer! nature.com/articles/s4158…
Many thanks to our collaborators @Barandunlab, Kai Ehrenbolger for their great effort to determine the cryoEM structure of EfrCD💪💪☺️
Extremely happy to have been part of this story published in Nature Chemical Biology! Thank you so much, Gianmarco, Sujani, @CedricHutter, Lea and Markus (Seeger Lab) and Jonas (@Barandunlab) for your hard work. nature.com/articles/s4158…
A new paper from Seeger Lab and @Barandunlab used deep mutational scanning to reveal the drug efflux profile for EfrCD, identifying critical residues for its activity in response to different drugs. Free to read: rdcu.be/c0zK1 nature.com/articles/s4158…
Researchers from @Barandunlab report the structure of a compacted microsporidian proteasome bound by an endogenous inhibitory protein. Kai Ehrenbolger #microsporidia #cryoEM go.nature.com/3HybcAv
Preprint : Ribosome clustering and surface layer reorganization in the microsporidian host-invasion apparatus. biorxiv.org/content/10.110… We describe the fascinating infection apparatus of microsporidian parasites using Cryo-ET. Thanks to @Barandunlab Carlson Laboratory MIMS - Molecular Infection Medicine Sweden
Hey hey, if you like cell biology, virology, and enjoy Swiss chocolate. Join me at FMI science by applying for the lab manager position👇👇😃
Yay! Very proud of our "adopted" postdoc Himanshu Himanshu Sharma who completed this beautiful story in a very independent manner after joining our group. Aren't polar tubes fascinating? MIMS - Molecular Infection Medicine Sweden Umeå Centre for Microbial Research Integrated Structural Biology Umeå University
#Microsporidia use their polar tube to infect host cells. The ultrastructure of the #PolarTube reveals different states of the tube wall, transported cargo, and uniquely arranged #ribosomes along the tube wall. Himanshu Sharma @Barandunlab &co in #PLOSBiology plos.io/49wNKyt
#Microsporidia use their polar tube to infect host cells. The ultrastructure of the #PolarTube reveals different states of the tube wall, transported cargo, and uniquely arranged #ribosomes along the tube wall. Himanshu Sharma @Barandunlab &co in #PLOSBiology plos.io/49wNKyt
Our work on the fascinating Microsporidia Polar tubes finds a place on the cover of PLOS Biology latest issue. Check it out here journals.plos.org/plosbiology/ar…