During the development of multi-cellular animals, biochemical signals control the organization of cells to set up body axes. In mouse embryonic stem cell aggregates, tissue flows are now found to amplify the formation of such body axes. nature.com/articles/s4156…

Congratulations Citi Lab for your latest publication in Nature Communications A feedback circuitry involving γ-actin, β-actin and nonmuscle myosin-2 A controls #tight #junction and apical cortex mechanics unige.ch/medias/en/2025… Molecular & Cellular Biology Dept 🔬 Geneva 🇨🇭 Faculty of Science | UNIGE

The flow features of cell monolayers depend on cellular interactions. Now four different types of cell monolayer are shown to exhibit robust conformal invariance that belongs to the percolation universality class. nature.com/articles/s4156…

1️⃣For years, scientists have known that mechanical tension influences cell behavior. But in our recent study in Nature Materials we found that it is not just the amount of tension—it is the direction! nature.com/articles/s4156…

Very happy and excited to share that this work is now published in Nature Physics ! rdcu.be/eigWi Faculty of Science | UNIGE Université de Genève Institut Polytechnique de Paris École polytechnique

Rigidity transitions in a 3D active foam model of cell monolayers with frictional contact interactions biorxiv.org/content/10.110… #biorxiv_biophys

Published Physical Review Letters! How nonreciprocity affects the behaviour of topological defects? they are reshaped, their annihilation can be enhanced or hindered, +1 -1 charges move differently. PhD work of YRouzaire Facultat de Física UB #ubics with ignacio pagonaba DPearce journals.aps.org/prl/abstract/1…

Fluid inside #Drosophilia oocytes spontaneously forms a vortex that spins around the ellipsoid-shaped cell’s long axis. Simulations and 3D imaging show that the direction of this self-organized #cytoplasmic flow is determined by the cell’s geometry. 🔗 go.aps.org/3EYg5no

Mechanobiological mechanism of cyclic stretch-induced cell columnarization dlvr.it/TKdwss

thinking nematic analysis, thinking 3D tissues? here's a cool new tool by @juliaeckert.bsky.social that does exactly that!

Fast, flexible, learning-free organoid quantification and tracking with OrganoSeg2 Cameron J. Wells, Najwa Labban, Shayna L. Showalter, Roza K. Przanowska, Kevin Janes doi.org/10.1101/2025.0…

New tool created by @juliaeckert.bsky.social for quantifying nematic order on curved surfaces. #cellnematics

1/4 Gut renewal is not passive “crowd control.” Instead of being pushed out by crowding or dying from apoptosis, cells compete in a mechanical tug-of-war. Weaker cells are eliminated—reframing intestinal homeostasis as a force-regulated process. science.org/doi/10.1126/sc…

📣New preprint: Mechanochemical feedback, tissue geometry & rigid-body dynamics initiate rotational migration in Drosophila via spontaneous chiral symmetry breaking. A mechanism generalizable to closed epithelia. Sreejith Santhosh biorxiv.org/content/10.110…

Wnt signaling modulates tissue mechanics, actin order, and regeneration in Hydra vulgaris biorxiv.org/content/10.110… #biorxiv_biophys

🎉🎉 We finally have a website! 🎉🎉 Did you miss a thread? Want to know who our delegates are? Do you want to join our big club? Check it out: epithelialmechanics.github.io Huge thanks to all thread-contributors and to you for following us!

Which features of tissue flows are most robust and how do they emerge from #EpithelialMechanics? I’m Alex Plum (Serra group @ UC San Diego) and I’ll be sharing some papers on characterizing and controlling avian gastrulation flows.