FDA consider pimavanserin for AD psychosis tomorrow. Erick’s thread shows how a protocol amendment to make primary at 6/52 (only point where placebo and drug separated) was made 10 months after data collection completed. Of course, it was also completely due to placebo worsening.

🚨Thrilled to share our lab’s first paper!🚨Excited to present our discovery that the #cytoplasm can divide without #nuclei, and do this periodically independently from the #cellcycle oscillator! biorxiv.org/content/10.110… "Oh?! What’s the mechanism and function” I hear? 1/🧵👇🏼

⚡️Save the date⚡️Free webinar 12.15-1.15 - 07.09.22 Listen to the report authors 'in conversation' discussing the messages from this report⬇️Everyone welcome, get the link by emailing [email protected] with the subject 'webinar'. Healthcare Quality Improvement Partnership RCPsych CCQI #mentalhealth #physicalhealth

📢DON'T MISS! ⏰12:30pm on Monday July 4th Kate Brown and Laura Hemmings will be discussing the role of physio in mental health with Physio Matters lunchtime live show 💻Streamed live over FB, YouTube, Twitter, Linkedin and Twitch.

Children and adolescents with early onset psychosis (#EOP) at least as likely to have recurrent copy number variants (#CNVs) as children and adolescents with autism. Possible implications for genetic testing in #CAMHS Via 22Q11 Ireland ajp.psychiatryonline.org/doi/10.1176/ap…

Great to see that the dramatic treatment effect on appetite and weight is sustained long term. A stunning example of how disrupted central melanocortin signalling can drive increased appetite and obesity and how this can be reversed by activating the MC4R, I'd be v interested to/

Here’s a very important #ECG that was recorded in a 50-year-old lady shortly before she suddenly went into cardiac arrest What’s the diagnosis?

After metformin, which medication should be next for patients with type 2 #diabetes? Long-awaited results from the GRADE trial, which compared the effect of four glucose-lowering medications, have been published in NEJM. jwat.ch/3Srp2qA

A trial of food delivery robots in Cambridgeshire could soon be expanded after receiving a thumbs up from shoppers. This will be discussed at the Highways and Transport Committee next week (Tuesday, 4 October). Read more here: orlo.uk/spU5S

A young male with hx of depression came with confusion, diarrhea, diaphoresis. He takes citalopram, tramadol & duloxetine at home. Vitals w/⬆️BP, HR,⬆️⬆️temp. Labs w/AKI, ⬆️CK. What is the excess neurotransmitter & diagnosis? #Medtwitter (David Juurlink)

A study involving twin boys with excessive caloric intake and low body weight revealed a variation in a classic pathway of energy production. nej.md/3VjQlVL

“Go see this patient in the ED with ST changes.” #ECG #CardioTwitter #MedTwitter #FOAMed

I am grateful to have been invited by South Today to talk about #gambling #harms and the newly launched #NHS service for the treatment of those. tom hepworth was a great host. I hope this will raise awareness of this important public health issue.

Shoutout to docs with visible and/or invisible disability. We at Royal College of Psychiatrists “Disability Task & Finish group”, led by Lade Smith CBE & 🌈 Rajesh Mohan are keen to hear your top 3 recommendations for workplace accommodation/support for NHS employers. Mhairi Hepburn @SueMcCowan1 #MedTwitter

Is 2023 the year you want to start volunteering or get a new job as you recover from mental health difficulties? If so, our Career and Employment Coaching service can support you on your journey. More information: lght.ly/1fo6971 #MentalHealth #Career

A free workbook and podcast for the family and friends of someone with an eating disorder, written by experienced carers cpft.nhs.uk/keeping-safe-p…. Carers at CPFT P.E.D.S 🌠 F.E.A.S.T. The SUN Network Beat @EriRoseP Caraline Anna Conway Morris 🇬🇧🇪🇺🔶🌈 AnnaTuke #EDAW2023

There’s this guy on TikTok who does nursery rhymes in the style of his favourite bands and the production standards are insane. This Mumford and Sons style rendition of You Are My Sunshine is genuinely as good as a song they would release

Dr Akeem Sule ⁦ak411⁩ on Focusing on people not symptoms: the consultant psychiatrist | The BMJ ⁦⁩ ⁦Dr Sule & Dr Inkster⁩ ⁦The BMJ⁩ ⁦Royal College of Psychiatrists⁩ ⁦rcpsych GAP⁩ ⁦Psychiatric Resident Doctors' Committee (PRDC)⁩ ⁦EPUT⁩ bmj.com/content/381/bm…

An international study led by #Addenbrookes will continue its search to find drugs that protect the most vulnerable patients from Covid, Dr Rona Smith reassured at a conference in Italy today, Friday 16 June. 📖 Read more orlo.uk/O5KDJ #Excellent

To help somebody who wants to end their own life you need to understand why - their personal circumstances, recent experiences, relationships, mood, and so on. Just checking for mental incapacity or coercion as in Leadbeater #AssistedDying bill is inadequate.