🤣 the real housewives of stem COULD NOT feature female scientists🤣 all female scientists I know, follow here or that have mentored me, are busy doing science. It’s the prominent male scientists firing shots and providing that rich content Bravo is looking for 🤣 #RHOSTEM

Join Howard Chang at “Bridging RNA Biology and Therapy: Exploring the Frontiers of Advanced Medicine” from Oct 9-11 at Cima in Pamplona, Spain! Hear from top speakers on the latest RNA research and therapeutic applications. Register now! 👉 doctaforum-events.org/2024/rnasympos… #RNAResearch

Attention prospective postdocs! The Azrieli International Postdoctoral Fellowship for Research at Israeli Universities in STEM, Humanities, and Social Sciences is now open for applications! You can apply today for the 2025–26 cohort. The Azrieli International Postdoctoral

For the Molecular Cell RNA focus issue, I put together a piece featuring the voices of Li Yang, Igor Ulitsky 💔, Wendy Gilbert, Chengqi Yi, ule_lab, and @maiwench on the challenges of investigating RNA function: authors.elsevier.com/a/1jt7A3vVUPRm…

We are excited to report the discovery of TIGRs, a widely-occurring RNA-guided system found in bacteria and their viruses. TIGRs consist of a peculiar repeat region which is transcribed into RNA and processed into multiple guide RNAs to direct TIGR-associated proteins to their

Getting closer to organism level metabolism on a chip!

Linus Pauling already knew!

Identification of molecular determinants of gene-specific bursting patterns by high-throughput imaging screens dlvr.it/TJNjwL

Let's do CRISPRa without virus and plasmids!!! Congratulations to Tobi and all the authors ! It was a really fun project, revealing some exciting results! academic.oup.com/nar/article/53…

KnockTF: a comprehensive human gene expression profile database with knockdown/knockout of transcription factors Now KnockTF 2.0 👤🐭🌱🌽 >1400 transcriptomes ~800 TF/TcoF licpathway.net/KnockTF/index.… Go to "Search" for your TF "Quick Search" does not work Nucleic Acids Res 2020

I'll be in Boston/NYC/UPenn for <72 hrs this week explaining why Weizmann Institute is the best school there is. If you know anyone that it can be relevant for - please DM me for details.

So cool!

EPB41L4A-AS1 long noncoding RNA acts in both cis- and trans-acting transcriptional regulation and controls nucleolar biology biorxiv.org/content/10.110… #biorxiv_molbio

Feedback appreciated!

So cool!

Our lab is expanding! We are looking for an experimental or computational PhD student and a Technical Assistant for a project on RNA localization regulation. Details 👉 shorturl.at/fWH3u ⏳ +1 more PhD spot still open—10 days left to apply! shorturl.at/Udw0Q #PhD

In a medical milestone, a customized base editor was developed, characterized in human and mouse cells, tested in mice, studied for safety in non-human primates, cleared by U.S. FDA for clinical trial use, manufactured as a complex with an LNP, and dosed into a baby with a severe,

Today in Science Magazine we report the development of a laboratory-evolved CRISPR-associated transposase (evoCAST) that supports therapeutically relevant levels of RNA-programmable gene insertion in human cells, a collaboration with Sternberg Lab. 1/13 drive.google.com/file/d/1I-UbCR…

Stop the doom scrolling! A new 🗞️ from my lab, describing one of our flagship projects of many years we are super excited to share: "Inducible formation of fusion transcripts upregulates haploinsufficient CHD2 gene expression". A 🧵biorxiv.org/content/early/…

Where do you host the bigWig/bigBed files for your UCSC genome browser hubs? (pro-Iran hackers thought that our "nuclear RNA-seq" track data was, well, *nuclear* and yada yada yada we need a new server)