Check out Journal of Orthopaedic Research - Spine® study on mouse model for spinal ligament #ossification, simulating chronic #spinalcord compression seen in #OPLL patients. Delving into neurobio-, radiolo-, and pathological changes. Check it here: doi.org/10.1002/jsp2.1… ORS Spine Section ORS Preclinical Models Section

New @JORSpine study uses #Mendelian randomization to uncover causal links between inflammatory cytokines and disc degeneration. Key cytokines: #IFNγ, #IL1b, #IL4, #IL18, #SDF1a, and #GCSF show significant associations with IDD risk. > doi.org/10.1002/jsp2.1… ORS Spine Section

A recent study by Zhang et.al. in Journal of Orthopaedic Research - Spine® developed an automated Lenke classification system utilizing innovative deep learning algorithms for preoperative evaluation of adolescent idiopathic scoliosis (AIS). #ORSSMC Orthopaedic Research Society onlinelibrary.wiley.com/doi/10.1002/js…

new research in Journal of Orthopaedic Research - Spine®! This study introduces an automated CNN technique to classify lumbar disc and facet joint health from MRI images, aiming to enhance the interrater reliability of Pfirrmann and Fujiwara grading systems. 📈🧠 👉 doi.org/10.1002/jsp2.1… ORS Spine Section

@JORSpine is busy! New study reveals that volumetric brain measurements can predict #AIS using #MachineLearning. Random forest algorithm achieved impressive accuracy, highlighting brain regions as predictors. Read more here: doi.org/10.1002/jsp2.1… ORS Spine Section Scoliosis Research Society

New research in Journal of Orthopaedic Research - Spine® sheds light on metabolic disorders in the pathogenesis of ossification of the ligament flavum. Using #bioinformatics , the study highlights key metabolic and immune factors involved. 🧫🔬 Check: doi.org/10.1002/jsp2.1… ORS Spine Section #lumbarspine

New findings in Journal of Orthopaedic Research - Spine®; study performs analysis of neuromuscular junctions in bilateral paraspinal muscles of #AIS patients, highlighting neuromuscular factors as potential therapeutic targets. 💪 Read their study: doi.org/10.1002/jsp2.1… ORS Spine Section Scoliosis Research Society

New Journal of Orthopaedic Research - Spine® report shows how compressive loading & swelling speeds up cryoprotectant delivery in IVDs; ⏫ high cell viability after cryopreservation. Big step for full disc transplantation & research! See: doi.org/10.1002/jsp2.1… ORS Spine Section #RegenMed #Spine

New Journal of Orthopaedic Research - Spine® report shows 3-month #romosozumab treatment improves regional bone mineral density & biomechanical parameters in elderly patients with osteoporosis undergoing spine surgery. See full study: doi.org/10.1002/jsp2.1… ORS Spine Section #spine #bone

New @JORSpine #insilico study examines different #GDF5 doses on hNP cells. 🌟 Findings: 0.25 & 1 mg doses could be effective for matrix synthesis?! Key insights for #RegenMed? Explore the study: doi.org/10.1002/jsp2.1… #Orthopedics #SpinalCare ORS Spine Section ORS Preclinical Models Section

New report in Journal of Orthopaedic Research - Spine® uncovers collagen damage in AF tissues of DDD patients with CHP staining. 🔍 Results show strong correlations in degradation markers, offering new insights into DDD pathology. Check it out: doi.org/10.1002/jsp2.1… #SpineCare #RegenMed ORS Spine Section

Out in Journal of Orthopaedic Research - Spine®: Research uncovers important molecular markers and immune cell changes in hypertrophic ligamentum flavum. Highlights include #TGFβ and #TNF pathways. Valuable insights for understanding spinal fibrosis. See the details: doi.org/10.1002/jsp2.1… ORS Spine Section

Recent Journal of Orthopaedic Research - Spine® article examines the impact of axial compression and distraction on cervical facets under flexion. Results show increased facet strains with higher compression, indicating a potential rise in fracture risk. doi.org/10.1002/jsp2.1… #Biomechanics ORS Spine Section

New work Journal of Orthopaedic Research - Spine® shows model to predict annulus fibrosus fiber orientations from disc geometry alone. 🌟 Results match experimental data in bovine and human discs, highlighting important fiber asymmetries. Explore the study: doi.org/10.1002/jsp2.1… ORS Spine Section

Congratulations to Alikhan Fidai Alikhan Fidai on his article published in @JORSpine exploring a flexible material (FPLA) for mechanically augmenting tissue engineered intervertebral discs (TE-IVDs) in a porcine model Cornell BME Cornell Engineering @ORSSpineSection onlinelibrary.wiley.com/doi/epdf/10.10…

New pub in Journal of Orthopaedic Research - Spine®: This research preliminarily illustrated the vital role of metabolic disorder in the pathogenesis of ossification of the ligamentum flavum using bioinformatic algorithms and experimental validation for metabolism-related genes buff.ly/3PKuLIF #ORSSMC

Congratulations to C3EN Joyce Chapman Community Grantee John Martin of @rushmedical on receiving a Journal of Orthopaedic Research - Spine® Early Career Research Award & a Spine Section Early-Stage Investigator Award at the Orthopaedic Research Society 7th Int'l Spine Research Symposium! Read more at c3en.org/2025/01/22/joy…

PSA: The Orthopaedic Research Society Social Media Committee (SMC) will cross-post the latest publications from Journal of Orthopaedic Research® and Journal of Orthopaedic Research - Spine® across X, Bluesky, and LinkedIn. We aim to share the latest advances in orthopaedic research with you wherever you look for science content! #ORSSMC

As ORS Social Media Committee Chair, I am excited to welcome our new Social Media Liaisons (#ORSSML)! Randeep, Nesa, Nicholas, and Ahmed will be sharing the latest Journal of Orthopaedic Research® and Journal of Orthopaedic Research - Spine® articles on your feed in addition to our fabulous committee members. 👏 Orthopaedic Research Society

In honor of the Kentucky Derby this week, the #ORSSMC is excited to highlight some of the stellar Veterinary Scientists in the @orssociety, and their research in the areas of #sexdifferences, #animalhealth, & #onehealth. Stay tuned on May 1, 2, & 3 for more! #ORSxDerby #KyDerby