
Jordan Smoller
@jorsmo
Psychiatry, Genetics, Epidemiology, Precision Medicine. Author of The Other Side of Normal. 3% Neanderthal. Now on BlueSky jorsmo.bsky.social
ID: 34516232
https://smollerlab.org 23-04-2009 03:26:54
6,6K Tweet
3,3K Followers
1,1K Following



"what neural substrate sets this speed limit on the pace of our existence? Why does the brain need billions of neurons to process 10 bits/s? Why can we only think about one thing at a time?" The unbearable slowness of being: Why do we live at 10 bits/s? sciencedirect.com/science/articl…

Clinical genomicist Heidi Rehm has spent more than two decades helping change the culture in clinical genomics labs by encouraging data-sharing. Learn more about Rehm’s background as an organizer and community builder in a new Broad feature story: broad.io/HeidiFeature


From Vinay Prasad MD MPH and colleagues pointing out that median duration of antidepressant RCTs= 8 wks while in real-world median use is 5 years and questioning evidence base for long-term use. Fair point though is this unique to ADs as opposed to say CVD meds? medrxiv.org/content/10.110…

Our new paper on continuous-time, dynamic suicide attempt risk prediction is now published online at npj Digital Medicine. Using a large-scale electronic health records database, we adapt neural ODEs—naturally suited for modeling evolving latent states like suicidal tendencies and




Don't miss this year's conference including marion Leboyer Steve Hyman Roy Perlis John Torous, MD MBI Husseini Manji Olu Ajilore, MD, PhD - @pshrink.bsky.social and many more. Early bird pricing available till May 1

📢Work w/ Chris Kennedy Dr. Taylor Burke Jordan Smoller Jasmin Brooks Stephens, Ph.D. + others📢 Clinicians stratify patients for risk of suicide attempt at above chance levels in routine practice, but statistically incorporating routinely collected info during suicide risk assmt improves predictive accuracy

In a new study, researchers from MGH Psychiatry used machine learning to enhance the accuracy of predicting suicide risk. The study was published in JAMA Psychiatry. Read more: jamanetwork.com/journals/jamap… Kate Bentley @c3k Dr. Taylor Burke Jordan Smoller


Great piece from Atul Gawande newyorker.com/news/the-lede/…

another example of how research = hope nytimes.com/2025/04/27/hea… Gina Kolata






How polygenic score effects vary by context and interacting contexts with Mihael Cudic Justin Tubbs Tian Ge Putting Polygenic Scores in Context: How Intersectional Factors Affect Relative and Absolute Genetic Risk medrxiv.org/content/10.110…