Our first deposit at bioRxiv and a study we’re super proud of! biorxiv.org/content/10.110…

Here, we discuss the many actions of insulin in skeletal muscle, including GLUT4 translocation, glycogen deposition, lipid accretion, and protein deposition. doi.org/10.1016/j.cmet… Such a joy to write this with my science heroes Erik A. Richter and Amira Klip🙏

Excited for this to come out! Real collaborative effort and the 1st first author paper of my PhD, co-first with Mladen Savikj 🥳

Breaking sitting marginally lowers glycemic variability; new research in press: journals.physiology.org/doi/abs/10.115… #obesity #insulinresistance #glycemia #lipids Karolinska Institutet Baker Institute Australian Catholic University Juleen R. Zierath Anna Krook @JohnAHawley Brendan Gabriel Jonathon Smith Mladen Savikj

Our latest, in press AJP-Endocrinology and Metabolism 🤓

Frequent activity breaks from sitting may improve fasting blood sugar (glucose) levels and stabilize daily fluctuations. Our new study is highlighted this month AJP-Endocrinology and Metabolism Congrats Jonathon Smith Mladen Savikj and team!

What mitochondrial ATP synthesis actually looks like 😨 #medtwitter

Our latest: Three wks of interrupting sitting lowers fasting glucose & glycemic variability, but not glucose tolerance, in free-living women & men with obesity ⁦Jonathon Smith⁩ ⁦Mladen Savikj⁩ ⁦AJP-Endocrinology and Metabolism⁩ pubmed.ncbi.nlm.nih.gov/34151582/ via @NYTimes nytimes.com/2021/09/08/wel…

Last week's most mentioned article is from AJP-Endocrinology and Metabolism: Three weeks of interrupting #sitting lowers fasting #glucose and glycemic variability, but not glucose tolerance, in free-living women and men with #obesity ow.ly/f0jY50G9KWU

Childhood hero. Bumped into him randomly once, on holiday. Took the time to chat to a young fan and aspiring keeper. Meant the world to me. Absolute legend. RIP #TheGoalie

Distinctive exercise-induced inflammatory response and exerkine induction in skeletal muscle of people with type 2 diabetes. Nicolas J. PILLON SRP DIABETES science.org/doi/10.1126/sc…

Our MetaMEx.eu database now includes mouse transcriptomics. We hope this will help reduce animal use in research by providing useful data on #exercise responses. Thanks @UtanDjurforsok for the support! #myotwitter

No, skeletal #muscle cells do not respond to extracellular #succinate. Makes sense: they don't have the receptor SUCNR1/GPR91! New #research from us Karolinska Institutet published in AJP-Endocrinology and Metabolism journals.physiology.org/doi/full/10.11…

Our ‘Exercise metabolism and adaptation in skeletal muscle’ Review is out in Nature Reviews Molecular Cell Biology! Learnt a lot writing this with Kevin Murach KenDyar and Juleen R. Zierath. Be sure to check out the supp too - good amount of info there that we weren’t able to fit in the main text 🏃‍♀️🏋️ 🧬

We've just published a tour-de-force Review on the metabolic regulation of skeletal muscle in response to exercise 💪🏼🏃🏾 Fantastic effort by the authors: Jonathon Smith Kevin Murach KenDyar Juleen R. Zierath This Review is free to access for 30 days! go.nature.com/3IGMr4E

I really like this comparison of mouse and human muscle by KenDyar and Jonathon Smith. This is in the supplements of the Nature Reviews Molecular Cell Biology article with Juleen R. Zierath. Don’t overlook the bonus coverage! #myotwitter nature.com/articles/s4158…

Nice this work is finally out: “Myotube growth is associated with cancer-like metabolic reprogramming and is limited by phosphoglycerate dehydrogenase”. See 🧵 from Henning Wackerhage 👇

After what feels like the shortest 6 years, I had the pleasure of defending my thesis last week! 🤓 Thanks to Marcas Bamman, PhD Emma Andersson @teixeiralabki and Michael Svensson for great questions and a really fun discussion 🧬 #PhDone

Nice to have our latest up on bioRxiv 🤓 Here we build upon previous work from us (and others) to investigate NR4A3 in the context of skeletal muscle inactivity 🧬 Feedback welcome!

Our latest study connects reduced NR4A3 expression with physical inactivity and indicates that NR4A3 downregulation in human muscle has adverse effects on glucose metabolism and protein synthesis. Congrats to Jonathon Smith Brendan Gabriel Nicolas J. PILLON & team! sciencedirect.com/science/articl…