We've offered our scientific resources & expertise to help the Government's fight against #coronavirus by increasing @PHE_uk's & NHS's capacity to test for #covid19 300 of our researchers have volunteered to help scale up testing. More here ⬇️ crick.ac.uk/news/2020-03-1…

Wow, IdoAmitLab Eran Elinav and their colleagues at the Weizmann Institute are setting up a massive corona testing facility. This sounds fantastic. Are others following? Can we do this? cees dekker - also at @ceesdekker.bsky.social Alexander van Oudenaarden Oncode Institute instagram.com/tv/B-OwA7-gZMP…

Read this story on Marvin Tanenbaum, Hans Clevers and Lude Franke's important work related to COVID-19, rediscovering a sense of community in times of crisis and the importance of basic science: tinyurl.com/y9p6z64s Hubrecht Institute UMCG

Thanks to Lenno Krenning, Jonne Raaijmakers and Rene Medema for covering Andrew Holland 's and our work in their nice news & views in the The EMBO Journal embopress.org/doi/full/10.15…

I am very excited to share our new manuscript on how Nuclear Lamina (NL) may regulate gene expression and promote drug resistance! 🧬💊 biorxiv.org/content/10.110…

Have you ever considered that a CRISPR-Cas9 break in a gene can accidentally trigger transcription activation instead of generating a KO? Here we show how 👇 (thread) biorxiv.org/content/10.110…

Monosomies, trisomies and segmental aneuploidies differentially affect chromosomal stability biorxiv.org/cgi/content/sh… #bioRxiv

Very proud of Dorine Hintzen and Mar Soto RdelaT for their hard work and interesting results on the relationship between aneuploidy and CIN. Also thanks to all the co-authors!

Check out our latest work on aneuploidy tolerance, kudos to Dorine and Jonne and their coworkers for making this happen #mitosis #aneuploidy. Monosomies, trisomies and segmental aneuploidies differentially affect chromosomal stability biorxiv.org/content/10.110…

Happy to share our paper on monosomy, out just today. Great work from Narendra Chunduri and Paul Menges, awesome collaboration with Korbel, Kschischo, Willmund labs: Systems approaches identify the consequences of monosomy in somatic human cells disq.us/t/41c9d2t

Happy to share our latest work on monosomies versus trisomies differentially affecting fitness. Thx to all collaborators. journals.plos.org/plosone/articl… #aneuploidy

Nice to see this out! Very interesting! We still know so little about monosomy.

Check out our latest publication on the differences between monosomies and trisomies and their impact on CIN. Thanks to all who contributed! journals.plos.org/plosone/articl…

We are excited to share our new pre-print! We show that a previously-thought meiotic protein, MND1, has an important role enabling repair of two-ended DNA double-strand breaks in somatic cells. Great effort from everyone involved!

Can double-stand break (CRISPR/Cas9) toxicity vary between different chromatin environments? We studied it. Excited to share these insights with you. Great collaboration with Lisa Koob, MedemaLab Rene Medema and Wilbert Zwart lab. doi.org/10.1093/nar/gk…

Interested in DNA damage repair? I'm excited to present our paper highlighting the role of the meiotic protein MND1 in somatic cells now out in Molecular Oncology 🔬 Thanks to all the co-authors for their amazing help! #dnarepair #homologousrecombination

Check out our latest pre-print on adaptation to aneuploidy! Thanks to everyone who contributed Dorine Hintzen Mar Soto RdelaT Michael Schubert Rene Medema

Can cells adapt to aneuploidy? Our new study reveals that reducing chromosomal instability and inflammation is key to adaptation. Thanks for everyone that contributed! Michael Schubert Mar Soto RdelaT Jonne Raaijmakers Rene Medema embopress.org/doi/full/10.10…

Excited to share our latest publication in Cell Reports where we reveal the critical role of SRBD1 in mitotic chromosome segregation. Read more here: tinyurl.com/y9cfkw4h A big thanks to all our wonderful collaborators - This wouldn't have been possible without you!