🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Tremendous to see this out today. Thanks to all the collaborators far and wide and the study’s co-pilots Chris Horne and John Scott

New study highlights how RIPK1 is essential for ZBP1 driven necroptosis, a key immune response against viruses like HSV. Targeting RIPK1 could offer new antiviral strategies for herpes. #HerpesResearch #Virology journals.plos.org/plosbiology/ar…

The kinase RIPK3 promotes neuronal survival by suppressing excitatory neurotransmission during central nervous system viral infection. Immunity cell.com/immunity/fullt…

We found that activating programmed necrosis through genetic or pharmacological interventions might be an effective anti-cancer-strategy in pancreatic cancer. Thanks to all collaborators and funders! Mathias Heikenwälder Heinrich-Heine-Universität Düsseldorf Maximilian Reichert nature.com/articles/s4146…

🎉Thrilled to announce that I have been awarded the Italian Science Fund-StG to start my research lab at the University of Milan Università degli Studi di Milano🇮🇹🔬 We'll study #RSV viral replication factories for novel #TPD antiviral strategies🦠 📢 We're #hiring soon! If interested, get in touch!📩

Thrilled to share new work led by Jie Yang in the lab published today in nature. We find that Aspirin prevents metastasis by releasing T cells from immune suppression by platelet TXA2. Cambridge University CRUK Cambridge Centre rdcu.be/eci1U

#EveryCellIsAnImmuneCell! Jie Yang Roychoudhuri Lab &co show nature that platelet-derived thromboxane A2 suppresses T cell functions favoring melanoma metastases! Aspirin or COX1 inhibition or deletion in platelets reduce metastases! #ScienceMatters doi.org/10.1038/s41586…

Opposing regulation of BAX and BAK by VDAC2 dictates their role as executioners of apoptosis and their therapeutic targeting Science Advances science.org/doi/epdf/10.11…

Increasing evidence for the central role of peroxisomes in antiviral immunity. A new study provides in vivo evidence to support a role for peroxisomes in SARS-COV-2 infection. Kudos to the authors on this important study. science.org/doi/10.1126/sc…

The loss of TBK1, or both TBK1 and the related kinase IKKε, results in uncontrolled cell death–driven inflammation. We show that TBK1/IKKε prevent premature cell death by limiting the activity of multiple death pathways in myeloid cells.FabianFischer science.org/doi/10.1126/sc…

Announcing, one of a unique conference. #CellDeath, #Innateimmunity, and #Autophagy. Top speakers, top Science. website -open soon- Please retweet. EMBO DBT/WT India Alliance CCMB CSIR, India Jonathan Kagan Vishva Dixit Vojo Peter Deretic Veit Hornung Thirumala-Devi Kanneganti Clare Bryant ([email protected]) Ivan Đikić

💥Exciting new #postdoc opportunities in my lab CRUK Manchester Institute to study #NutrientHostMicrobiome interactions in #CancerImmunity in mice and humans. #CancerImmunology #MucosalImmunology #Microbiome ⏰Deadline: 4 April 2025 Apply👇 cruk.manchester.ac.uk/career/mi-24-5… ⏩RT

#WeekendRead! #NotOnlyInterferons! Nan Yan &co show Molecular Cell that other than inducing pathogenic IFNs in lysosomal storage disorders, STING function as a proton channel to activate TFEB & induce lysosomal repair cell.com/molecular-cell…

Here comes a new Trends in Cancer commentary on cool original data at Nature Cancer about #macrophages and #neutrophils in #breastcancer #immunoevasion #threeCs. Kudos to Lukas offtwitter for taking the lead. Fox Chase Cancer Center Cedars-Sinai Free at authors.elsevier.com/a/1kx%7EC8Z12y…

Structural basis of BAK sequestration by MCL-1 in apoptosis dlvr.it/TKFJFw

Happy to see our review out in ChemBioChem in which we describe the tools and strategies for deciphering linkage type-specific #ubiquitin signalling: doi.org/10.1002/cbic.2…. Thanks to Julian for spearheading this, and to Camilla Elbæk and Dominik for important contributions.

🚨We’re #hiring! 🧑‍🔬#Postdoc position is available in my newly established group at the University of Milan 🇮🇹 to study viral replication factories and develop innovative #antiviral strategies based on #TPD 🧬🦠 Join us for this exciting science! 🔬 🔗 Details below Please RT

Such a beautiful project and a pleasure to work with NguyenLab.bsky.social ! Please share and post our recent work Cell cell.com/cell-reports/f… from the CaldasLab Carlos Caldas 🇵🇹🇪🇺🇬🇧🎗 and Oscar M Rueda ! See the complete story in bluesky bsky.app/profile/nguyen… by Long

Here comes our Nature Immunology N&V on a recent nature paper by the Chi lab St. Jude on #mitochondria in the regulation of #IFN signaling in #cancer. Kudos to Katia Cosentino and Joost Verduijn! Ricerca Unimore Fox Chase Cancer Center Available at rdcu.be/emD1n

Cambridge Pride with research friends! Love is Love and we need to create a safe world for all!