Congress| #EHA2022 Jonas Jutzi, @BrighamHeme discusses the mechanisms by which CALR mut cells alleviate ER stress and how to exploit this. He highlights that disrupted proteasis results in dependency on the IRE1-XPB1 axis of the UPR and proteasome activity #MPN #medicalcongress

Congrats to Dr. Jonas Jutzi Mullally Lab @BrighamHeme on a fantastic oral abstract presentation European Hematology Association #EHA2022 today! Thanks to our fab collaborators Anna Nam Fatima Al-Shahrour Peter van Galen & proteomics Broad Institute, also funders The Leukemia & Lymphoma Society @nih_nhlbi gabriellesangels.org #MPNsm

Very happy and grateful to share our latest publication in Blood, hot off the virtual press: ashpublications.org/blood/article/…

Thank you @BloodJournal ASH for highlighting our paper! Jonas Jutzi @AnnaMarneth @BrighamHeme Brigham and Women’s Research Dana-Farber Broad Institute @ElfLabUChicago Anandi(she/her) @anandikrishnan.bsky☮️🇮🇳🇺🇸 Stanford Medicine Fatima Al-Shahrour CNIO Stop Cancer @nih_nhlbi Leukemia & Lymphoma Society Research gabriellesangels.org #MPNsm

Happy to share our story on how megakaryocyte reprogramming in breast cancer produces platelets that promote metastasis. Thanks to all of our collaborators who saw this over the finish line! @SandraMcAllist4 Joseph Italiano @BrighamHeme @isabellecarlota science.org/doi/epdf/10.11…

Our paper is out! Read my latest #research in the Mullally Lab on CALR-mutated MPN, published in Leukemia. rdcu.be/c06E8. Big thanks to everyone! @AnnaMarneth @BrighamHeme Dana-Farber Broad Institute Fatima Al-Shahrour Anna Nam Peter van Galen @nih_nhlbi Leukemia & Lymphoma Society Research #MPNsm

My fundraising team and I aim to "Kick cancer in the butt"! Please join Cycle for Survival and raise money for rare cancer research at Memorial Sloan Kettering Cancer Center. You can help build a better future for people worldwide. secure2.convio.net/mskcc/site/TR?…