#GroundSquirrel develop “reversible #cataracts” during #hibernation, with their lenses quickly clearing upon waking. Using GS-#iPSC-derived lens epithelial cells, we explored the molecular mechanism behind this, pointing to a potential treatment target. jci.org/articles/view/…

Check out this Current Biology dispatch article Jeremy Kay and I wrote for a new article from the Julie Lefebvre lab! Neuroscience: The dynamic development of dendrites: cell.com/current-biolog…

Our lab's paper led by Sam Ing-Esteves on HOW the clustered Protocadherins (cPcdhs) produce dendrite self-avoidance and complex neuronal morphologies was published today in Current Biology: authors.elsevier.com/a/1jgpv3QW8S6F… The Hospital for Sick Children (SickKids) Department of Molecular Genetics, U of T

In sum, this paper shows that the cPcdhs mediate dendrite self-avoidance through self-recognition and retraction. Congrats to Sam Ing-Esteves for tackling my dream project, managing the quantifications it entailed 😬, and enlightening us all on what cPcdhs do in vivo.

And check out Sarah Hadyniak, PhD & Jeremy Kay 's views here in their Dispatch: sciencedirect.com/science/articl…

Congrats Julie Lefebvre Sam Ing-Esteves! Beautiful work. Sarah Hadyniak, PhD and I enjoyed writing a summary of your article for Current Biology — read it here: authors.elsevier.com/a/1jpcG3QW8S6F…

Going to Society for Neuroscience (SfN) #SfN2024 in Chicago? Come to our GLIA+NEUROIMMUNE social MON 10/07! beth stevens & I will be there, along with SchaferLabUMassChan, Klaus-Armin Nave, Harwell Lab, Asya Rolls, Jonathan Kipnis 💔🎗️, Michael Heneka, Erin Gibson. rumors of @Dr_Oligo's 2024 afterparty are true!

Check out our preprint on new recombinant tools for reversibly ablating excitatory and inhibitory synapses. biorxiv.org/cgi/content/sh… Thanks to amazing first author Aida and collaborators Rich Kramer , Dave Chenoweth and Robert Campbell.

Do you need to express Cre in astrocytes? Our GfaABC1D-Cre-4x6T plasmid is now available as a packaged virus from Addgene! blog.addgene.org/new-viral-vect…

Come see us at #SfN2024 in Chicago! The Duke Neurobiology Graduate Training Program booth will be open from 📅Saturday to Tuesday, ⏰12-2 PM. Meet with students, faculty, and learn about joining our world-class research community Duke Neurobiology!

Are you interested in synaptic balance, astrocytes, neurons, and neurodevelopmental disorders? The Irala lab is recruiting and we have postdoc and technician positions! They come with incredible benefits and support! Please apply following the links below to join our team 🧬✴️

New collaborative @bioRxiv alert, with Dario Tommasini, Karthik Shekhar and Takeshi Yoshimatsu about the molecular and evolutionary relationships across vertebrate rods and cones: biorxiv.org/content/10.110… a mini thread...

Generation of morphologically distinct astrocyte subtypes from human iPSCs reveals a link between glial shape, function and reactivity biorxiv.org/cgi/content/sh… #biorxiv_neursci

Excited to share our new paper in Current Biology! 🚀📄 "Retinal direction of motion is reliably transmitted to visual cortex via highly selective thalamocortical connections" cell.com/current-biolog…

Horace Barlow, by all accounts, was thinking about 30 years ahead of his time. Here is a transcript of the opening keynote I gave at a symposium honoring Horace's scientific legacy: markusmeister.com/2024/12/14/hor….

Kicking off the new year with our new paper in nature! We find that touch-guided tongue control in mice relies on a collicular mechanosensorimotor map, analogous to collicular visuomotor maps associated with visually-guided orienting in many species. nature.com/articles/s4158…

Close your eyes and bring your full attention to the sensation of your tongue making contact with a tooth of your choice. Take 3 big breaths. Do you 'see it?' ...Our latest in nature by the indomitable Brendan Ito Jason Gao and Brian Kardon

FETCH enables fluorescent labeling of membrane proteins in vivo with spatiotemporal control in Drosophila biorxiv.org/content/10.110… #biorxiv_neursci

Hey look - it’s our new preprint! If you’re interested in microglia in the developing CNS - not just the retina - we hope you’ll check it out.

We have innovated design of templates for CRISPR/Cas9 editing which allows efficient introduction of epitope tags in vivo. It is a simple hack which we hope to be broadly useful. Work by talented graduate student Chuanping Zhao. nature.com/articles/s4146…