🍾New preprint from us! We found it puzzling that rare and common variants do not affect the same genes in autism. In this project, we generalize TWAS to trio data and highlight a key TF POU3F2 that regulates many ASD genes affected by rare mutations biorxiv.org/content/10.110…

Glad to share with you guys our lab’s new paper. Please try out TITANS. It has a very clear guideline in the github page.

Our work that attempts to boost methylation coverage from Illumina450K to EPIC. bioRxiv viewer disq.us/t/3p5yst2 Resources at: github.com/GangLiTarheel/…

Great work from our lab👏🏻

Please check out the newest work from my previous group.

Super excited to share our new work.🌟 Simulated offspring has many potential usage. With vcf/bcf file as input, ORIGAMI can provide you as many simulated offspring as you want (in bfile). Please give ORIGAMI a try and we are excited to see other creative applications!

Our work that carefully evaluated Hi-C data enhancement methods for enhancing PLAC-seq and HiChIP data: academic.oup.com/bib/advance-ar… Always enjoyed collaboration with Ming Hu

I am thrilled to share our variant-to-function study for Alzheimer's disease in microglia: online today Nature Genetics. Wonderful collaboration with Yin Shen! Thanks also to Gan Lab

✨Thrilled to share STimage-1K4M, an open-source dataset featuring 1,149 spatial transcriptomics slides and ~4M sub-tile images-gene expression pairs! STimage-1K4M is ideal for multi-modal learning in medical imaging. Can't wait to see your creative uses!