What a PERFFect day to share our new preprint! With Tsion Abay #BobStickels Meril Takizawa @ChaligneRonan and Ansu Satpathy, we introduce PERFF-seq, a new experimental approach to studying rare cells with scRNA-seq via transcript-specific enrichment. biorxiv.org/content/10.110… 1/n

What a cool new technology! Nice work! Opens up many avenues to get enriched scRNA data!!

PERFFect method from PERFFect trainees. congratulations to Tsion Abay Caleb Lareau #BobStickels and team!

.ASCI honors Howard Chang Howard Chang with the 2024 Stanley J. Korsmeyer Award for his contributions to genome science through his invention of mapping technologies and his discoveries of long noncoding RNAs (lncRNAs). buff.ly/3xjOvwO

Attending Life Science Innovation Northwest next week? Our VP David G Kugler, PhD will present a company overview on Wed., April 17 at 1:40pm PT. Stop by to learn how Cartography is building a differentiated pipeline of antibody-based #cancer therapies: bit.ly/3J9XXp4

I defended my PhD thesis!

Cartography CEO Kevin Parker, PhD sat down with Sarah Jones of Pear VC for the latest episode of Pear Biotech Bench to Business. Check it out to hear the latest on Cartography & insights on building a discovery pipeline based on new #cancer targets: bit.ly/3yeJ5DN

We're thrilled to announce our strategic collaboration with Gilead Sciences to discover and develop therapies for patients with triple-negative #breastcancer and the most common form of non-small cell #lungcancer, adenocarcinoma. Learn more: businesswire.com/news/home/2024…

Congratulations to Kevin Parker Chester Wong + the team at Cartography Biosciences on their collaboration w/ Gilead Sciences that will leverage Cartography's platforms to identify novel targets, pushing the boundaries of treatment for triple-negative breast cancer & adenocarcinoma.

Whats great for patients AND long-term economic value is investing in the systematic ID of the best possible antigens for ADCs/TCEs/CAR-T. Excited for Cartography to partner with Gilead on this

Take a listen: Our CEO Kevin Parker, Ph.D., shares how our newest collaboration with Gilead Sciences is bringing us one step closer to shaping cancer #immunotherapy for those with triple-negative #breastcancer and adenocarcinoma.

Congratulations to HHMI Investigator Howard Chang, who has been awarded the Foundation for the National Institutes of Health 2024 Lurie Prize in Biomedical Sciences for his work revealing the importance of long noncoding RNA in gene regulation & its impact on human disease: hhmi.news/3RdYsTp

HHMI Foundation for the National Institutes of Health I am grateful and very honored for this recognition. Many thanks to my collaborators, trainees, and mentors for their wisdom and support.

LY6G6D is the next DLL3

Incredibly excited that our paper linking single molecule states of TF binding to gene expression using quantitative thermodynamic models is out in Nature today. An amazing collaboration with the Bintu Lab. Congrats to Ben, Michaela, and Julia! nature.com/articles/s4158…

Excited to welcome Howard Chang to Amgen 🧪🔬🧬 as our new SVP for Research & CSO! A pioneering physician-scientist, Howard’s expertise in genetics, oncology, & inflammation will help us push the boundaries of discovery. We’re excited to embark on this journey together to redefine the

I am excited to join storied biotech pioneer Amgen 🧪🔬🧬 as Chief Scientific Officer and Head of Research. I look forward to partnering with my new colleagues to deepen understanding of biology and develop solutions to the most pressing medical challenges tinyurl.com/5n86sku5

Congratulations to my mentor, colleague, and friend Howard Chang ! Howard is a once-in-a-generation scientific mind and leader and will transform drug discovery at Amgen and throughout the industry.

CHOIR is officially published Nature Genetics. No more arbitrary decisions in clustering. Add this to your single-cell toolbox - it will save you so much heart ache. And now it can scale to millions of cells. Compliments of the very talented Cathrine Sant (Petersen).

Our work on 3D genome organization in human cancer is out! In collaboration with Yanding Zhao Howard Chang William J. Greenleaf and TCGA we used HiChIP to profile enhancer connectivity and rewiring in primary tumors. nature.com/articles/s4158…