Spacedust: de novo discovery of conserved gene clusters. Combining sensitive Foldseek structure search and conserved neighborhood detection to discover functionally-associated gene clusters in prokaryotic & viral genomes. 🚀github.com/soedinglab/spa… 📄biorxiv.org/content/10.110… 1/6🧵

Doing good science is 90% finding a science buddy to constantly talk to about the project.

MGnify Proteins – our vast database of protein sequences derived from metagenomic sequencing – is now accessible via the web (ebi.ac.uk/metagenomics/p…) and via Google Cloud BigQuery Public Datasets. For the full news, see ebi.ac.uk/about/news/upd…

Joanna Slusky 🫖 Also all the folks involved in high throughput DNA sequencing, sequence databases, sequence alignment and sequence search... 🙏

In the year of our lord 2024, how is this still a thing?! Nature Portfolio

Excited to share our preprint titled: "COmapper: High-resolution mapping of meiotic crossovers by long-read sequencing in Arabidopsis" on BioRxiv! doi.org/10.1101/2024.1… COmapper enables high-resolution CO maps from F1 hybrid pollen and F2 seedlings using nanopore sequencing.

I'm excited to share that a pipeline I prototyped during my undergrad is now available as a preprint! COmapper maps meiotic crossover sites using ONT reads extracted from pollen! Simply put, it detects transitions from maternal to paternal SNPs in pollen genomes of F1 hybrids.

Just published in nature! Research by Google DeepMind including Nobel Laureate Demis Hassabis introduces a novel technique for reliably identifying LLM-generated content. At its core, this approach subtly alters the next-token sampling process to introduce minor adjustments

Antibodies are highly diverse, but most possible sequences are unstable or polyreactive. In this work led by Milind Jagota, we propose a new source of data for modeling constraints from these properties. Our models show clear improvements in predicting antibody dysfunction.(1/n)

In 1956, 26-year-old Edgar Dijkstra invented a classic path-finding algorithm while out with his fiancée at a café in Amsterdam. It all happened in his head: “Without pencil and paper you are almost forced to avoid all avoidable complexities,” he said. quantamagazine.org/computer-scien…

Excited to be speaking CSHL Meetings #cshlmbiome this week about our latest work on the neonatal gut microbiome—just out last month in Nature Microbiology nature.com/articles/s4156…

You can always trust @thesteinegger to select the most informative names to his useful databases! @milot_mirdita #cshl_microbiome

@milot_mirdita just delivered an excellent talk CSHL Meetings covering viral protein structure database, homology detection, multi-protein complex alignment and multiple protein alignment using 3D structures. Awesome collaborations lead to impactful work! @thesteinegger soeding_lab

For anyone looking to classify metagenomic sequences, Metabuli from @thesteinegger is the tool for you! Big thanks to CSHL Meetings for organizing the microbiome meeting.

It was a great honor to give a talk infront of researchers leading the microbiome field 😁 I really hope to join #cshlmbiome again !!

Big thanks to soeding_lab CSHL Meetings Marie Skłodowska-Curie Actions for giving an opportunity to share my research work.

오늘 국회 앞 인파 2번이고, 3번이고 탄핵 가결될 때까지 끝까지 함께 싸워주십시오. 저희도 흔들리지 않고 탄핵만을 향해 가겠습니다. 부결 시 내일(8일) 오후 3시, 다시 국회 앞으로 모여주십시오. 시간은 변경될 수 있습니다. 자세한 공지는 계정 메인트에 있는 공식 공지 <촛불 n호>를

🚀 New Metabuli DB is out! It contains quality-filtered GTDB, RefSeq viruses, and the human T2T. Prokaryotes follow the GTDB; viruses and the human follow NCBI taxonomy. Download it and expand with genomes of your choice using "updateDB" command. metabuli.steineggerlab.workers.dev

We’re thrilled to launch the first ISCB RSG KOREA webinar! Open to anyone, anywhere — all are welcome. Join us and follow ISCB RSG KOREA to stay updated on future events.