👋 I am a group leader @ Leeds, focused on the study and engineering of translation control in bacteria. Our interests span 🦠 Synthetic biology 🧬 Protein synthesis 🎨 Fluorescence 🧮 Quantitative biology and 📈 Data analysis. Lots going on over the next few weeks, stay tuned!

🚨New PhD in my lab on "Understanding how micro- and macro-nuclei support adaptation in Paramecium"! This project will use advanced Oxford Nanopore sequencing approaches to understand how Paramecium adapt by altering the content of their different nuclei. 🧬 findaphd.com/phds/project/f…

Survivor’s photo from the Imperial Bioeng SynBio labs clean-up-and-quiz-day 🍻 Bioengineering Imperial College Centre for Synthetic Biology Rodrigo Ledesma-Amaro Ouldridge group @ Imperial Naomi Nakayama Stanley Lab

🔎🧬Want to target your #metabarcoding study across kingdoms, get quantitative results, and use long-read sequencing to really understand the biodiversity present? A final year project student in my lab, Lucia , has you covered using Cas9-based enrichment! doi.org/10.1101/2024.1…

Been a brilliant year for our lab - wonderful to share a merry afternoon in a warm London pub with this great bunch 🎄🎄🎄🎄🎄🎄🎄🎄🎄🎄

Iterative SCRaMbLE for Engineering Synthetic Genome Modules and Chromosomes biorxiv.org/cgi/content/sh… #biorxiv_synbio

2024's top 10 advances in biology (🧵) 1. Progress in longevity Blocking the pro-inflammatory cytokine, IL11, extended healthspan and lifespan (in mice!) Old mice without IL11 look healthier, they're stronger, and they live longer nature.com/articles/s4158…

BIG news in synthetic biology!!! 🔬…and it’s actually very tiny. The world’s first synthetic eukaryotic genome is complete! The final chromosome in a synthetic yeast genome for baker’s yeast was completed by the Sc2.0 project. go.nature.com/4hJuscS

Plz RT: my lab has 14 exciting new openings available now to work on different aspects of synthetic genomics. cailab.org/open-positions/

*ALERT* If you are a bioengineer (or related), if you use synthetic biology for health-related applications, and you wish to start your own lab in a neat place (Naples), in a fantastic research institute, stay tuned, a call will be coming out! DM me if you want to have more info!

Wake up babe, a new NGS platform just dropped

Joaquin Caro Astorga's SubtiToolKit paper is published today. This cloning toolkit for Bacillus and Geobacillus was years of effort and indepedent work by J.Caro-Astorga, first in my lab and then with Erika Alden DeBenedictis at the Crick. It's been a journey! sciencedirect.com/science/articl…

Girl with Bacteria

Right, who wants to VOTE for some amazing yeast bioart done by our Synthetic Biology undergrad students in the Bioengineering department? ⬇️

Looking for a PhD ? I have a fully funded one for UK nationals on engineering gene circuits in probiotic microbes. Will bring together a lot of existing stands of #synbio research in my group and push towards some exciting applications! Start date will be Sept 2025. Pls RT

📢📢 UK researchers in Engineering Biology of all levels (students, technicians, postdocs, PIs, CTOs and CEOs) - what are your thoughts about using AI in your work? The UK government is looking to gather views to shape policy via a survey. If you have 10 min spare please do it.

It's 25 yrs to the day since the Human Genome Project & Craig Venter declared joint victory in sequencing the human genome - an ideal time for Wellcome to annouce their new project, involving our lab, to begin work towards synthesising human genomes wellcome.org/news/researche…

Please RT and share! We have up to two PhD positions available in my group for entry in fall 2026, applications expected in fall 2025. DM me if interested!

New stickers 🧬🩷 I will be giving these out at the Genome Science conference later this week!

Online now @ Cell is the yeast multicellular engineering paper from Fankang Meng - the fruits of his productive PhD. He developed modular synthetic biology tools to bring multicellular behaviours to yeast - adhesion, juxtacrine signalling and more. cell.com/cell/fulltext/…