New criteria help to determine if mouse stem cell line shows true totipotency 🔹 Collaboration with The Hospital for Sick Children (SickKids) and Karolinska Institutet 🔹 #kuleuven team featuring @vincentpasque 🔹 Paper in Nature Cell Biology (10.1038/s41556-020-00609-2) bit.ly/3btKzfO

How can genes decode information with a defined logic? In our new bioRxiv led by Rutger Gjaltema 🧬 and @TSchwammle we dissect the regulatory landscape of Xist and find a distal-proximal hierarchy that generates a logical AND-gate. biorxiv.org/cgi/content/sh… A thread

Very excited to share with you our pre-print linking Wnt deregulation with carboplatin resistance in Breast Cancer! Willy Antoni Abreu de Oliveira Dept of Development and Regeneration - KU Leuven Stem Cell Institute #Wntpathway biorxiv.org/content/10.110…

Excited to share our work published in Science Magazine led by our DPhil @LisaRodermund, jointly supervised by Lothar Schermelleh and us. (1/3) science.sciencemag.org/content/372/65…

I have just published Deep Learning on Human Microbiome at Medium / Towards Data Science nikolay-oskolkov.medium.com/deep-learning-…

Delighted to share the latest PayerLab preprint about the implications of #Xchromosome activity on meiotic entry in #mouse primordial germ cells #PGCs in vitro biorxiv.org/content/10.110… 1/

Thrilled to share our paper on the mutational landscape of human somatic and germline cells nature. We integrated histology and genomics to explore the genetic diversity that develops within our bodies as we age. nature.com/articles/s4158… An illustrated tweetorial… [1/15]

Excited to share our latest publication out Cell where we explore how Xist nucleates local protein gradients to propagate gene silencing during X chromosome inactivation. 1/15 dlvr.it/SBxrs9 🧫🧬🔬🧵

Our paper describing gene regulation in the fly brain is out now in nature! So proud of this one and of the amazing team work with Sara Aibar Ibrahim I. Taskiran and @joynismail in the @steinaerts lab! Check it out here go.nature.com/3ETX2EF with below our main findings:

Excited to share our latest work in Science Magazine (science.org/doi/10.1126/sc…). Building on the foundational work of the PCAWG and HMF consortia, we established a compendium of mutation events in somatic whole-genome sequencing data of 3,949 patients from 19 tumor types.

On May 8th, I was at work and it happened to be Mother’s Day. I started the day thinking: “Today we have the chance of making new Moms”. I don’t know if it was the positive energy but all our patients of that day became pregnant🤰🏻 This work will never stop to amaze me ✨

🎉 Happy to share our study, now out in Nature Cell Biology! This is the result of an amazing collaboration of our lab @vincentpasque (KU Leuven) with Rugg-Gunn Lab (Babraham Institute), Hendrik Marks (Radboud University) & Maarten Dhaenens (UGent). A 🧵… [1/19] nature.com/articles/s4155…

Confused by all the "what is epigenetics" discourse? Well I have just the thing for you -- presenting the Epigenetics Alignment Chart!

Happy to share our recent publication about conventional IVF, where we reviewed strengths and weaknesses of one of the most practiced assisted reproductive technology (ART) approaches used worldwide. lnkd.in/dR7GaA3C #ivf #science #reproduction #fertilitytreatment