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Check out the inimitable @valerieJsydnor 's latest masterpiece below -- linking development of thalamocortical structural connectivity to cortical developmental plasticity in 3 datasets with a new bundle atlas. Massive effort with awesome collabs at #pennlinc + many others.

The Data Science & Sharing Team (DSST) at NIMH is hiring an early to mid-career Data Scientist. Stop by poster 1408 or 1707 to meet some current and former members of our team. #OHBM2024 Apply by July 1st. Please Retweet! github.com/nimh-dsst/data…

Assessing CT-based Volumetric Analysis via Transfer Learning with MRI and Manual Labels for Idiopathic Normal Pressure Hydrocephalus medrxiv.org/cgi/content/sh… #medRxiv

Thrilled to share our preprint introducing ComBatLS, a new data harmonization method that preserves covariates’ (e.g. age and sex) effects on variance! (1/2) biorxiv.org/content/10.110…

Our paper is now out in Neuron! Neuron (details from preprint thread below, now with more results and containerized pipeline!) w/ Armin Raznahan @edbullmore Petra Vertes and amazing coauthors cell.com/neuron/fulltex…

Can lifespan brain charts from rhesus macaques inform our understanding of neurodevelopment across species? A new preprint by Ting Xu et al. presents detailed MRI-based normative trajectories for brain structure, based on 1,522 scans. Check it out here: biorxiv.org/content/10.110…

Curious about human brain development through an animal model? 🧠🐒Check out our new preprint on Brain Charts of the Rhesus Macaque Lifespan! We've mapped normative trajectories for macaque brains using 1.5k MRI scans from PRIME-DE and collaborators! biorxiv.org/content/10.110…

How are genetic risk for mental illness, personalized functional brain networks, and overall psychopathology related during early adolescence? New preprint out now medrxiv.org/content/10.110… and I'll be presenting a poster at #Flux2024 this Sunday! (1/17)

Wooo! Awesome new work from Kevin Sun integrating personalized functional networks, genomic risk, and clinical psychopathology!!

Multimodal data from 98 individuals: neuroimaging, genetics, dendritic spine morphometry, proteomics, and gene expression; identifies 100s of proteins that explain individual differences in MRI measures @HerskowitzLab nature.com/articles/s4159…

Multimodal data from 98 individuals: neuroimaging, genetics, dendritic spine morphometry, proteomics, and gene expression; identifies 100s of proteins that explain individual differences in MRI measures | Nature Neuroscience nature.com/articles/s4159…

It was such a special experience to see this groundbreaking paper in the making. The paper examines, among other things, ante-mortem functional connectivity and post-mortem omics ⭐️in the same people⭐️. Chockfull of wonders -- big congrats to @herkowitzlab and the whole team!

Great study by Gareth Ball @StuartJoldham Jakob Seidlitz and colleagues, linking molecular and anatomical descriptions of the prenatal brain, now out in Nature Communications: Molecular signatures of cortical expansion in the human foetal brain 🧠🧬 nature.com/articles/s4146…

Our recent publication and open source release of a de-identification tool to protect patient privacy while empowering #openscience of brain MRIs. Great collaborating with Benjamin Kann, MD Aaron Alexander-Bloch Jakob Seidlitz and their teams! Children's Hospital Penn Medicine Dana-Farber

✨Our paper, published in nature today, investigated how we can leverage study designs to improve the replicability of brain-wide association studies (BWAS). nature.com/articles/s4158…

Structural MRI of brain similarity networks — a Review by Isaac Sebenius, Lena Dorfschmidt, Jakob Seidlitz, Aaron Alexander-Bloch, Sarah E. Morgan & Edward Bullmore go.nature.com/3D6tMiF Isaac Sebenius Lena Dorfschmidt Jakob Seidlitz Aaron Alexander-Bloch Sarah Morgan

Absolutely delighted to see our review of structural MRI brain similarity networks out! The culmination of months of exciting conversations with co-first author Isaac Sebenius and the stellar team of Aaron Alexander-Bloch, Jakob Seidlitz, Sarah Morgan and Ed Bullmore!

⚡️New #preprint alert ⚡️ We show that #brain aberrations are highly heterogeneous after #preterm birth, and that there are consistent biological mechanisms and social environmental influences shaping these aberrations. 📰 Read the full preprint here: biorxiv.org/cgi/content/sh…

How can we increase the replicability of brain-wide association studies in a rigorous way? A nature paper by Kaidi Kang @kaidikang.bsky.social Jakob Seidlitz Richard Bethlehem Ted Satterthwaite Simon Vandekar et al identifies the relevant study design features that contribute nature.com/articles/s4158…

Comparing Brain-Behavior Relationships Across Dimensional, Tail-Sampled, and Propensity-Matched Models biorxiv.org/content/10.110… #biorxiv_neursci