The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds biorxiv.org/content/10.110…

Releasing the trap: How the segregase p97 extracts PARP1 from chromatin: cell.com/molecular-cell…

Congratulations to Elena Conti and F. Ulrich Hartl Max Planck Institute of Biochemistry (MPIB) on receiving the ERC Advanced Grants! ➡️ biochem.mpg.de/two-erc-advanc… ➡️erc.europa.eu/news/erc-2021-… #ERCAdG European Research Council (ERC) conti_lab

Ubiquitin-directed AAA+ ATPase p97/VCP unfolds stable proteins crosslinked to DNA for proteolysis by SPRTN sciencedirect.com/science/articl…

Such a pleasure to host this amazing crowd at our #ubfriends2022 #ubiquitinfriends2022 symposium!

Had a great time at the Ubiquitin & Friends Symposium in the beautiful city of Vienna! Thanks to the organisers for putting together such an amazing meeting, and for the Best Short Talk Prize. Thoroughly enjoyed discussing science in person! 😊 #ubiquitinfriends2022

More evidence for (A) macropinosome leakiness and (B) degradation of large aggregates by the proteasome (rather than autophagosome), in a nice study from Diamond Lab at UT Southwestern on the fate of internalized tau fibrils: jbc.org/article/S0021-…

Active conformation of the p97-p47 unfoldase complex: nature.com/articles/s4146…

Excited to debut XL01126 – a first-in-class PROTAC degrader for the protein kinase LRRK2, a high-profile target in Parkinson’s disease. Great #CeTPD collaboration with Dario Alessi MRC PPU team and Rui Moreira Please share, thread below doi.org/10.26434/chemr…

Want to understand the molecular architecture of cells? Investigate the structural basis of human disease in situ? We are looking for a postdoc to join our #teamtomo at Uni Göttingen ! Please RT and get in touch directly if interested!

We are recruiting! Open PhD student position to study the molecular mechanisms of #proteostasis #ubiquitin #proteasome. Join us in lovely Cologne Uniklinik Köln Universität zu Köln CECAD Cologne. Please RT! jobs-uk-koeln.de/index.php?ac=j…

Are you a #PhD and looking for new challenges? Do you want to join interdisciplinary projects on the regulation of #proteinsynthesis in health and disease? We have a job for you! 💼 ❕Apply until December 4th ❕mpg.de/19481534/postd… #joboffer #PostDoc #MolecularCellBiology

Please RT: We have an opportunity for an outstanding scientist to establish their research group at the Perutz! The successful candidate will be offered an #assistantprofessor position MedUni Wien. Read more: tinyurl.com/4hjm863y #facultyjobs #academicjobs #sciencecareers

New year, new chances? We have a #job for you! You hold a #PhD in the area of #lifesciences, and want to help shape the @IMPRS_LS #graduateschool training program? ❕Apply until January 22 ❕more information: mpg.de/19670943/coord… #joboffer #stellenangebot #MPIB

Joint Statement from German Postdoctoral Networks on the Eckpunktepapier from the BMBF postdocnet.mpg.de/127851/Stateme… with Munich Postdoc Network LeibnizPostDocs Helmholtz Munich PhD & Postdoc | Career Center @FMP_MDC_PDA Postdoc Appreciation Week Germany Sociedad CERFA Rede Apoena AWI Postdoc Team and more. #WissZeitVG #ichbinhanna

At ADPD 2023, scientists showed that biosensor cell lines that detect tau seeds do make tau fibrils. A chaperone tears them apart. Does this happen in the #alzheimersdisease brain? AD/PD - Advances in Science & Therapy @UTSWNews Max Planck Institute of Biochemistry (MPIB) @MRC_LMB ow.ly/4yyr50NEGeq

#India has become the first nation to reach the south pole of the #Moon after its Chandrayaan-3 probe successfully landed as planned. go.nature.com/44l0XHd #Chandrayaan3