Isaac Li (@isaaclilab) 's Twitter Profile
Isaac Li

@isaaclilab

Single-molecule biophysicist, CRC T2, MSFHR Scholar, building responsive DNA nanostructures to study biology. Views are my own. @fos_ubco @ubcokanagan 🇨🇦

ID: 155439196

linkhttps://lilab.ok.ubc.ca calendar_today14-06-2010 04:10:07

373 Tweet

374 Followers

523 Following

Isaac Li (@isaaclilab) 's Twitter Profile Photo

Our work on Altering Cell Junctional Tension in Spheroids through E-Cadherin Engagement Modulation just got published! We showed that E-cad tension can be monitored and modulated using membrane-anchored DNA probes and strand-displacement reactions! pubs.acs.org/doi/10.1021/ac…

Our work on Altering Cell Junctional Tension in Spheroids through E-Cadherin Engagement Modulation just got published! We showed that E-cad tension can be monitored and modulated using membrane-anchored DNA probes and strand-displacement reactions!
pubs.acs.org/doi/10.1021/ac…
David Sivak (@davidasivak) 's Twitter Profile Photo

Applications received by November 15, 2024 will receive full consideration. For a full description and application instructions, see sfu.ca/physics/about-… (For dual-career searches, tenure-track positions in other areas of Physics will be posted to this link soon.)

Isaac Li (@isaaclilab) 's Twitter Profile Photo

Thank you Biophysical Society of Canada, for this recognition! I'm truly honoured to be receiving this award. Huge shoutout to my fantastic team: this wouldn’t have been possible without them. We're excited to see what's coming in the next few years!

Rafeeque Mavoor (@rafeequemavoor) 's Twitter Profile Photo

Free scientific illustrations for biologists! 😍 NIH has released a library of 500+ free scientific illustrations to create figures, presentations, and illustrations! all freely available in the public domain. Retweet and spread the message! bioart.niaid.nih.gov

Free scientific illustrations for biologists! 😍

<a href="/NIH/">NIH</a> has released a library of 500+ free scientific illustrations  to create figures, presentations, and illustrations!   

all freely available in the public domain. 

Retweet and spread the message!
bioart.niaid.nih.gov
Isaac Li (@isaaclilab) 's Twitter Profile Photo

The tradition continues! UBCO Chemistry pumpkin carving contest organized by the CGSS! Check them out on FIP 3rd floor! 🎃🎃🎃👻👻👻 UBC Science Okanagan @UBCOGradstudies UBCO BCCU UBCO CCU

The tradition continues! UBCO Chemistry pumpkin carving contest organized by the CGSS! Check them out on FIP 3rd floor! 🎃🎃🎃👻👻👻 <a href="/fos_ubco/">UBC Science Okanagan</a> @UBCOGradstudies <a href="/bccu_ubco/">UBCO BCCU</a> <a href="/UBCO_CCU/">UBCO CCU</a>
Biophysical Society of Canada (@biophyscanada) 's Twitter Profile Photo

Celebrate #BiophysicsWeek w/ 3 trainee-organized virtual events to connect, learn, and have fun: 🧠Trivia Night – Mar 24, 6PM ET 🎤Career + Research talk Isaac Li – Mar 27, 1:30PM ET 🥖Biophysical Gastronomy – Mar 29, 2PM ET 📍Register here: events.teams.microsoft.com/event/dd0a3371…

Celebrate #BiophysicsWeek w/ 3 trainee-organized virtual events to connect, learn, and have fun:
🧠Trivia Night – Mar 24, 6PM ET
🎤Career + Research talk <a href="/IsaacLiLab/">Isaac Li</a> – Mar 27, 1:30PM ET
🥖Biophysical Gastronomy – Mar 29, 2PM ET
📍Register here:
events.teams.microsoft.com/event/dd0a3371…
Isaac Li (@isaaclilab) 's Twitter Profile Photo

We just published a review on recent progress in integrin force loading rate measurement using various molecular tension probes. Learn more about how this has advanced the field and what potential improvement lies ahead here: doi.org/10.1017/qrd.20… #mechanobiology

We just published a review on recent progress in integrin force loading rate measurement using various molecular tension probes. Learn more about how this has advanced the field and what potential improvement lies ahead here: doi.org/10.1017/qrd.20…
#mechanobiology
Isaac Li (@isaaclilab) 's Twitter Profile Photo

David Bakker from my group is talking to middle school students about our research on DNA and optical tweezers!🧬Great job, David, for bringing the latest science to the grade 6-10 classrooms! career.sd83.bc.ca/2025/03/14/fro… #biophysics #outreach

David Bakker from my group is talking to middle school students about our research on DNA and optical tweezers!🧬Great job, David, for bringing the latest science to the grade 6-10 classrooms!  career.sd83.bc.ca/2025/03/14/fro…
#biophysics #outreach
Biophysical Society of Canada (@biophyscanada) 's Twitter Profile Photo

The 10th annual BSC meeting is coming up in Hamilton! Don't miss the April 15 deadline for early registration, abstract submission, and travel awards. Details & program: event.fourwaves.com/bsc2025/ #BSC2025

The 10th annual BSC meeting is coming up in Hamilton! 

Don't miss the April 15 deadline for early registration, abstract submission, and travel awards.

Details &amp; program: event.fourwaves.com/bsc2025/ #BSC2025
Biophysical Society of Canada (@biophyscanada) 's Twitter Profile Photo

The 10th annual meeting of the Biophysical Society of Canada will be held May 20-23 at McMaster University in Hamilton, ON. Check out the speaker lineup and programs here: event.fourwaves.com/bsc2025/ Early registration and abstract submission deadlines are April 15. #BSC2025

The 10th annual meeting of the Biophysical Society of Canada will be held May 20-23 at McMaster University in Hamilton, ON.

Check out the speaker lineup and programs here: event.fourwaves.com/bsc2025/

Early registration and abstract submission deadlines are April 15. #BSC2025
Isaac Li (@isaaclilab) 's Twitter Profile Photo

Check out our recent progress using 🧬 PAINT kinetics to decode molecular tension in super-resolution force imaging! 🔬 Great team effort from Seongho, Adam, Irving, and Kevin! 👏 #DNAPAINT #tension #integrin #superresolution #adhesion doi.org/10.1002/advs.2…

Paul Wiseman (@pwmagi) 's Twitter Profile Photo

Methods and Applications in Fluorescence MAF 2025 August 24-27 in Montreal Canada Abstract deadline for talk consideration May 12 Abstract deadline for poster presentations June 2 Early Registration deadline June 25 Join us in Montreal for MAF 2025! maf2025.org/en

Methods and Applications in Fluorescence MAF 2025 August 24-27 in Montreal Canada
Abstract deadline for talk consideration May 12
Abstract deadline for poster presentations June 2
Early Registration deadline June 25
Join us in Montreal for MAF 2025!
maf2025.org/en
Isaac Li (@isaaclilab) 's Twitter Profile Photo

Latest from the lab:🧬Decoy DNA🧬can extend the lifetime of DNA-based tension probes >24h by outcompeting DNases and preserving signal integrity in live-cell tension imaging - simple, general strategy for robust mechanobiology in DNase-rich environments. doi.org/10.1002/anie.2…

Latest from the lab:🧬Decoy DNA🧬can extend the lifetime of DNA-based tension probes &gt;24h by outcompeting DNases and preserving signal integrity in live-cell tension imaging - simple, general strategy for robust mechanobiology in DNase-rich environments. doi.org/10.1002/anie.2…
Angewandte Chemie (@angew_chem) 's Twitter Profile Photo

Isaac Li and team show that adding excess decoy DNA protects DNA-based probes from DNase degradation, preserving probe integrity for over 48 hours and enabling robust, long-term mechanobiology studies in live-cell environments #openaccess 🔓 onlinelibrary.wiley.com/doi/10.1002/an…