Isaac Klein (@isaacaklein) 's Twitter Profile
Isaac Klein

@isaacaklein

Chief Scientific Officer at Dewpoint Therapeutics. @dewpoint_tx. Oncologist Scientist. Science + Medicine = Progress.

ID: 1011597233421279233

calendar_today26-06-2018 13:09:09

36 Tweet

230 Followers

68 Following

Ann Boija (@boijaann) 's Twitter Profile Photo

Check out our review about Biomolecular condensates and cancer. Fun to write this together with Richard Young and Isaac Klein. authors.elsevier.com/c/1cNFW5TA51TI…

MIT Biology (@mitbiology) 's Twitter Profile Photo

Condensates are membrane-less organelles that compartmentalize proteins and RNA. Here, Ann Boija, Isaac Klein & Richard Young summarize how studying condensates advances our understanding of cancer and could lead to novel therapeutics. Via Cancer Cell: bit.ly/35C5dGU

Condensates are membrane-less organelles that compartmentalize proteins and RNA. Here, <a href="/BoijaAnn/">Ann Boija</a>, <a href="/IsaacAKlein/">Isaac Klein</a> &amp; <a href="/youngricka/">Richard Young</a> summarize how studying condensates advances our understanding of cancer and could lead to novel therapeutics. Via <a href="/Cancer_Cell/">Cancer Cell</a>: bit.ly/35C5dGU
Whitehead Institute (@whiteheadinst) 's Twitter Profile Photo

We are thrilled to announce that two papers from Whitehead Institute researchers are in the running for STAT' annual biomedical research tournament, #STATmadness! Cast your vote in the first round today! MIT Biology MIT Science statnews.com/feature/stat-m…

Whitehead Institute (@whiteheadinst) 's Twitter Profile Photo

Whitehead Institute is neck and neck in this round of #STATmadness! Help us out by voting for our paper from the Young Lab Richard Young on where cancer drugs go in the body. ow.ly/ynu750DVvvQ

Whitehead Institute is neck and neck in this round of #STATmadness! Help us out by voting for our paper from the Young Lab <a href="/youngricka/">Richard Young</a> on where cancer drugs go in the body. ow.ly/ynu750DVvvQ
Isaac Klein (@isaacaklein) 's Twitter Profile Photo

Congratulations to a great team on this Mass General / Dana-Farber / Brigham family collaboration! "Impact of cancer history on outcomes among hospitalized COVID-19 patients". pubmed.ncbi.nlm.nih.gov/33856099/

Isaac Klein (@isaacaklein) 's Twitter Profile Photo

Thrilled to join Dewpoint Therapeutics as Chief Scientific Officer. Thanks for welcoming me to the team. Onward! dewpointx.com

Dewpoint Therapeutics (@dewpoint_tx) 's Twitter Profile Photo

We're delighted to welcome Isaac Klein to our team as Chief Scientific Officer. His expertise and intense interest in the meeting point between #BiomolecularCondensates and disease will prove invaluable as we advance programs toward the clinic. dewpointx.com/news/dewpoint-…

Dewpoint Therapeutics (@dewpoint_tx) 's Twitter Profile Photo

We’re pleased to announce the close of our series C financing. As the leader in #condensate drug discovery and development, we’re excited to further our platforms and add new capabilities to help advance potential therapeutics for patients affected by a wide range of diseases.

Leaps by Bayer (@leapsbybayer) 's Twitter Profile Photo

Congratulations to the whole Dewpoint Therapeutics team on reaching this important milestone. ​ We're proud to support you in your mission to translate condensate biology into treatments for the world’s toughest diseases.

Endpoints News (@endpts) 's Twitter Profile Photo

SoftBank led a $150 million Series C for Dewpoint, the company announced Thursday. Those funds will be enough to carry Dewpoint into the clinic at the end of 2023, while advancing a suite of 19 other programs. endpts.com/softbank-leads…

Isaac Klein (@isaacaklein) 's Twitter Profile Photo

Congratulations to the fantastic Dewpoint team on this remarkable achievement! Onward! fiercebiotech.com/biotech/dewpoi…

Isaac Klein (@isaacaklein) 's Twitter Profile Photo

I am humbled and grateful to be listed as one of Endpoints 20 under 40 in biopharma. A big thanks to the world-class team at Dewpoint, to whom this honor really belongs. Together, anything is possible. Onward! endpts.com/the-201-under-…

Dewpoint Therapeutics (@dewpoint_tx) 's Twitter Profile Photo

Congratulations Isaac Klein on this well-deserved acknowledgement! We are fortunate at Dewpoint to have an oncologist, #condensate scientist, and leader whose knowledge and passion for drug discovery will guide our progress as we advance toward the clinic.

Dewpoint Therapeutics (@dewpoint_tx) 's Twitter Profile Photo

Nature Reviews Drug Discovery published our groundbreaking perspective, "Modulating biomolecular condensates: a novel approach to drug discovery," a cohesive logic outlining how a deep understanding of condensate biology can revolutionize the drug discovery process. go.nature.com/3dH1TBq

Isaac Klein (@isaacaklein) 's Twitter Profile Photo

Congrats to the entire Dewpoint team! In this review, we explain the potential of condensate biology to unlock novel therapeutic opportunities for the most difficult diseases. It's a privilege to work with this world-class team on cutting-edge science for the benefit of patients.

Elie Dolgin (@eliedolgin) 's Twitter Profile Photo

“We have the observations that condensates form. Now we need to show why they are important.” My latest on biomolecular phase separation for @NatureNews: nature.com/articles/d4158… Thanks to Jonathon Ditlev TanjaMittag @PappulabWashU Richard Young KnowlesLab Cambridge @Isaac Klein &more

“We have the observations that condensates form. Now we need to show why they are important.”
My latest on biomolecular phase separation for @NatureNews: nature.com/articles/d4158…
Thanks to <a href="/Jonathon_Ditlev/">Jonathon Ditlev</a> <a href="/TanjaMittag/">TanjaMittag</a> @PappulabWashU <a href="/youngricka/">Richard Young</a> <a href="/KnowlesLabCamb/">KnowlesLab Cambridge</a> @<a href="/IsaacAKlein/">Isaac Klein</a> &amp;more
Isaac Klein (@isaacaklein) 's Twitter Profile Photo

A recent nature paper from The Conrad Lab piqued my attention: FSP1 inhibition via relocalization to condensates, inducing ferroptosis in cancer cells. This is a promising example of a condensate-modifying drug that induces condensate formation. nature.com/articles/s4158…

Isaac Klein (@isaacaklein) 's Twitter Profile Photo

In the last 5 years, Dewpoint Therapeutics has evolved and applied the science of condensates towards therapeutic discovery. It's a pleasure to share this article highlighting the progress in the field and at Dewpoint. Onward! bit.ly/45YJ9mn