Innate2Adaptive (@innate2adaptive) 's Twitter Profile
Innate2Adaptive

@innate2adaptive

Discovery science in protective and pathogenic immunity | @mnoursad, @BennyChain, @andimscience, @gpollara, @UCLInfectImm

ID: 2788514817

linkhttp://www.Innate2Adaptive.uk calendar_today28-09-2014 06:07:57

173 Tweet

726 Followers

251 Following

Casanova Lab (@casanova_lab) 's Twitter Profile Photo

Attached are the last three anti-TB posters sponsored by the Rockefeller Foundation in France before WWII. They advise on how to avoid or combat TB with simple measures of hygiene. Anti-mycobacterial drugs had not been discovered yet 😀

Attached are the last three anti-TB posters sponsored by the 
Rockefeller Foundation in France before WWII. They advise on how to 
avoid or combat TB with simple measures of hygiene. Anti-mycobacterial 
drugs had not been discovered yet 😀
UCL-TB (@ucltb) 's Twitter Profile Photo

Our London #WorldTBDay2019 symposium will be streamed live here: bit.ly/2VYhSwK (password is TBDay). Join us online if you can't be there in person. The day's lineup and timetable are at ucl.ac.uk/tb/world-tb-da… - talk titles to follow soon. LSHTM TB Centre The Francis Crick Institute

Our London #WorldTBDay2019 symposium will be streamed live here: bit.ly/2VYhSwK (password is TBDay). Join us online if you can't be there in person. The day's lineup and timetable are at ucl.ac.uk/tb/world-tb-da… - talk titles to follow soon. <a href="/LSHTM_TB/">LSHTM TB Centre</a> <a href="/TheCrick/">The Francis Crick Institute</a>
The HTD (@htropdis) 's Twitter Profile Photo

Excellent grand round The HTD from Gabriele Pollara on what causes pathology in Tuberculosis. The HTD we contribute to the North London TB Service bit.ly/2FsRBBa based Whittington Health NHS Trust where patients concerned they may have TB can be seen at one of our walk-in clinic

Excellent grand round <a href="/HTropDis/">The HTD</a> from <a href="/gpollara/">Gabriele Pollara</a> on what causes pathology in Tuberculosis. <a href="/HTropDis/">The HTD</a> we contribute to the North London TB Service bit.ly/2FsRBBa based <a href="/WhitHealth/">Whittington Health NHS Trust</a> where patients concerned they may have TB can be seen at one of our walk-in clinic
Casanova Lab (@casanova_lab) 's Twitter Profile Photo

Let's keep in mind that TB is not only infectious but also genetic, as shown in this classic 1943 paper. Defeating TB will require an understanding of its human genetic and immunological basis, at the molecular and cellular levels. academic.oup.com/jhered/article… #WorldTuberculosisDay

Let's keep in mind that TB is not only infectious but also genetic, as shown in this classic 1943 paper. Defeating TB will require an understanding of its human genetic and immunological basis, at the molecular and cellular levels. academic.oup.com/jhered/article… #WorldTuberculosisDay
Gabriele Pollara (@gpollara) 's Twitter Profile Photo

Blood transcriptional biomarkers improve stratification of short-term disease risk in TB contacts Up to 50% PPV for progression to active #TB! IDSA Team Mahdad Noursadeghi @antijroe Dr Cristina Venturini @rishgupta1986 Benny Chain Ibrahim Abubakar & Innate2Adaptive academic.oup.com/cid/advance-ar…

Blood transcriptional biomarkers improve stratification of short-term disease risk in TB contacts

Up to 50% PPV for progression to active #TB! <a href="/IDSAInfo/">IDSA</a>
Team <a href="/mnoursad/">Mahdad Noursadeghi</a> @antijroe <a href="/cristina_ventu/">Dr Cristina Venturini</a> @rishgupta1986 <a href="/BennyChain/">Benny Chain</a> <a href="/ProfIAbubakar/">Ibrahim Abubakar</a> &amp; <a href="/innate2adaptive/">Innate2Adaptive</a> 
academic.oup.com/cid/advance-ar…
Benny Chain (@bennychain) 's Twitter Profile Photo

Our latest paper using machine learning to discover early markers for disease risk in TB contacts is out in CID academic.oup.com/cid/advance-ar…

Gabriele Pollara (@gpollara) 's Twitter Profile Photo

Delighted to hear that our paper on tissue metabolism shaping immune responses to TB was one of JID's most downloaded papers in last 2 years! (esp cos only been out 1 year! 😉) #immunometabolism IDSA academic.oup.com/jid/article/21…

Gabriele Pollara (@gpollara) 's Twitter Profile Photo

Fantastic depiction of the powerful efficacy of vaccines against infectious diseases (source: sciencemag.org/news/2017/04/h… in @sciencemagazine)

Fantastic depiction of the powerful efficacy of vaccines against infectious diseases (source: sciencemag.org/news/2017/04/h… in @sciencemagazine)
Mahdad Noursadeghi (@mnoursad) 's Twitter Profile Photo

New post available in our group at UCL for a post-doctoral bioinformatician interested in functional genomics of human immune responses in tuberculosis: atsv7.wcn.co.uk/search_engine/… Please RT.

New post available in our group at UCL for a post-doctoral bioinformatician interested in functional genomics of human immune responses in tuberculosis: atsv7.wcn.co.uk/search_engine/…
Please RT.
David Stirling (@davidrstirling) 's Twitter Profile Photo

Our paper on QuantiFish - a #zebrafish fluorescence analysis tool - has been published in Scientific Reports! Many thanks to everyone involved, especially Gillian Tomlinson. nature.com/articles/s4159…

Rishi Gupta (@rishi_k_gupta) 's Twitter Profile Photo

New in Annals of the ATS... Q: What is the incremental value of the new TB2 antigen tube in the QuantiFERON Plus assay for predicting incident TB among recent contacts? A: It is highly correlated with the TB1 tube, so any added value is likely to be v. subtle! doi.org/10.1513/Annals…

New in <a href="/AnnalsATS/">Annals of the ATS</a>...
Q: What is the incremental value of the new TB2 antigen tube in the QuantiFERON Plus assay for predicting incident TB among recent contacts?
A: It is highly correlated with the TB1 tube, so any added value is likely to be v. subtle!
doi.org/10.1513/Annals…
Gabriele Pollara (@gpollara) 's Twitter Profile Photo

The UK has now performed >10,000 tests for #SARSCoV2! Can see clear increase in testing when case definition widened to increase Italy & Iran. Now >1200 tests / day 😯 Herculean effort by @PHE_uk labs from a standing start. #COVID19 (source: Department of Health and Social Care data).

The UK has now performed &gt;10,000 tests for #SARSCoV2! 

Can see clear increase in testing when case definition widened to increase Italy &amp; Iran. Now &gt;1200 tests / day 😯

Herculean effort by @PHE_uk labs from a standing start. #COVID19
(source: <a href="/DHSCgovuk/">Department of Health and Social Care</a> data).
UCL-TB (@ucltb) 's Twitter Profile Photo

Postdoc/RA position integrating cutting-edge human and zebrafish models to study the immunopathogenesis of TB, using transcriptomics and CRISPR

Dr Emily Shaw (@dremilyshaw) 's Twitter Profile Photo

I have a PhD😃🥂😮‍💨in TB Vaccinology With huge thanks to my supervisors Benny Chain & Mahdad Noursadeghi, my great pals in Innate2Adaptive & UCL Division of Infection & Immunity esp T cell vaccine Lab UCL 🧬👩🏽‍💻 & Tahel Ronel, my examiners and my family & all who provided childcare Dedicated to my dear father, Prof Richard Wise

Towerslab (@towerslab) 's Twitter Profile Photo

Our Nature Microbiology asking what’s special about pandemic HIV Capsid is finally out. Thanks to Lorena Zuliani Alvarez, PhD for her green fingers, patience and general brilliance. Here’s some answers to the questions we get from eg @stuartjdneil

Gabriele Pollara (@gpollara) 's Twitter Profile Photo

🚨NEW PREPRINT🚨 Ever wondered what the role of IL-6 was in TB? 🤔 A Mendelian randomisation analysis using data from 16 GWAS later... 🎯 Reduced IL-6 signalling ➡️ *lower* risk of TB disease! 1st author-Gus Hamilton #TB #Tuberculosis #IDtwitter medrxiv.org/content/10.110… 🧵 1/6

Mahdad Noursadeghi (@mnoursad) 's Twitter Profile Photo

TLDR: Blood RNA biomarkers for TB? ..still limited by specificity & can’t be used for confirmatory test. What about triage test? No advantage to direct Mtb PCR testing for people who produce sputum!