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Cells photographed through a microscope. Actin filaments are shown. #CellBiology

Let’s understand collective cell migration by breaking it down to its essential elements! I'm Leone Rossetti, and this is a thread showcasing what we can learn from cells journeying along narrow paths, and from the forces they generate. #EpithelialMechanics

New preprint from the lab! We studied how single cells migrate up, down and about fibronectin gradients. Experiments by Isabela Corina Fortunato, PhD , theory by David Bruckner. Collaboration with Edouard Hannezo and Raimon Sunyer IBEC biorxiv.org/content/10.110…

🚨 Excited to share our new paper: “Long-range organization of intestinal 2D-crypts using exogenous Wnt3a micropatterning”! 🔗 doi.org/10.1038/s41467… Let’s dive into how we used Wnt3a micropatterning to control intestinal epithelial organization. 🧵👇

Epigenetic regulation of placental vascularization – now published in Developmental Cell (sciencedirect.com/science/articl…). Congratulations and thanks to Stephanie Gehrs for fantastic work and paving the way of the augustinlab.de into the world of vascular epigenetics. There’s more to come!

A picture is worth a thousand words! Check how this start of amyloid fibrillation (cyan) in the vessel walls (dark blue) can lead to a 'leaky' blood-brain barrier. Accumulation of red blood cells (red) can compromise the function of these pyramidal neurons (orange). #NeuroCovid

Congratulations to Li-Kun and the team! Very significant findings! Curious to learn whether this process of aquaporin mediated migration will be operational in all tip cells!

The Vascular Biology & Disease Lab is recruiting one Postdoc to work on a fascinating project on blood vessels and sleeping sickness in collaboration with Luisa Figueiredo lab. More info: tinyurl.com/2cta2898

More than 40% of postdoctoral researchers leave academia, according to a study of some 45,500 researchers’ careers go.nature.com/42tQBro

We're back for another #SmallWorldInMotionMonday! Here we can see neutrophils, a white blood cell that helps protect from infection, gathering near the lymph node of a mouse 🐭. bit.ly/4hwupkv Credit: Dr. Olena Kamenyeva

Functional vascularisation of pancreas islets in vitro & in vivo, interesting study!

Cellpose3: one-click image restoration for improved cellular segmentation Carsen Stringer & Marius Pachitariu nature.com/articles/s4159…

Mechanical forces pattern endocardial Notch activation via mTORC2-PKC pathway. #DevBio elifesciences.org/articles/97268…

Proteins that allow water to move in and out of cells help shape the development of new blood vessels. elifesciences.org/articles/10630…

Stoked to present our latest, brilliantly led by Chris et al & Alejandro Torres-Sanchez. How tissues are patterned during development – we found that geometry-constrained ECM fractures pattern the myocardium in the vertebrate heart 1/n biorxiv.org/content/10.110…

Interesting review on engineering biological curvatures cell.com/trends/biotech…

Nature research paper: Dynamic cytoskeletal regulation of cell shape supports resilience of lymphatic endothelium go.nature.com/4hjYsvz

1️⃣For years, scientists have known that mechanical tension influences cell behavior. But in our recent study in Nature Materials we found that it is not just the amount of tension—it is the direction! nature.com/articles/s4156…

If you are interested in vascular malformations you may want check our new work published today Cancer Discovery , where we discover a somatic genetic event causing vascular malformations in PTEN hamartoma tumour syndrome (PHTS) aacrjournals.org/cancerdiscover…

ICTUS-BioGipuzkoa NeuroGermansTrias Neurovascular Research Lab (VHIR) Neuro_IdiPAZ Neurología HU La Paz Biogipuzkoa IGTP Vall d'Hebron Institut de Recerca IdiPAZ El día se ha completado con una foto de familia de la #RICORSICTUS con la subdirectora del Instituto de Salud Carlos III (ISCIII) Pilar Gayoso. Investigadoras/es en #ictus trabajando de forma coordinada para conocer, prevenir y mejorar el tratamiento de esta enfermedad