Only 1 more week to apply for this postdoc position on the genomics of parallel climate adaptation in yeast! Link to application portal is in the post below. Please share widely! 🧪🌳🧬🍄

Extracting NCBI SRA files with fasterq-dump can require 17x the size of the accession while decompressing. Our new tool xsra extracts sequences at 5x throughput with significantly less disk usage, built-in compression, and optional BINSEQ outputs github.com/arcInstitute/x…

The new issue of Genome Research is now live! Follow the link to a new ultra-long nanopore sequencing toolkit, a unified analysis of atlas single-cell data, and more! tinyurl.com/Genome-Res-35-5

Call for Papers! Genome Research is now encouraging submissions for a Special Issue on The Genetics and Genomics of Somatic Mosaicism, Guest Edited by Drs. Gilad Evrony, Eunjung Alice Lee, and Raheleh Rahbari. tinyurl.com/Call-for-paper… #BOG25 #KSMosaicism25 #MITS25 #somaticmosaicism

The peer-reviewed version of expansion in situ genome sequencing is now out in Science! The news is bittersweet – when we first revealed this last September, I never guessed it would be my final paper in academia, but a lot has changed. A few parting thoughts:

This weekend, we successfully hosted the Westlake Symposium for AI Virtual Cell at Westlake University. Brilliant minds from biology, multi-omics and AI came together to explore how how to build a virtual cell. Thank you all for joining us! #AIVC #AI #WestlakeUniversity

A 4-year postdoc position in population genomics is available in my group at the University of East Anglia, to work on a project sequencing a thousand fox genomes across rural and urban environments in the UK. vacancies.uea.ac.uk/vacancies/1593…

Welcome to attend our Symposium on Experimental Evolution. Co-organized by Dao-Qiong Zheng, Jing Li (李婧) and myself.

Excited to share #AlphaGenome, a start of our AlphaGenome named journey to decipher the regulatory genome! The model matches or exceeds top-performing external models on 24 out of 26 variant evaluations, across a wide range of biological modalities.1/6

🚨🚨 ATTENTION ATENCIÓN! Time is running out to submit your Abstract and request Scholarship for our Satellite SMBE Meeting in Patagonia. Deadline: 27/06/25 Abstract Submission Deadline: 30/06/25 play.4id.science/smbe025/login

For many of those who were asking on BLOW5 vs POD5 for nanopore signal data, here is a finally detailed benchmark we did: biorxiv.org/content/10.110… Summary: performance of BLOW5 is >= POD5 (from ~= to 100X, see below), with benefit of having ~3 dependencies instead of >50.

The Saccharomyces Genome Resequencing Project 5 (#SGRP5) will be presented by Gianni Liti at #ICYGMB32 in Paris 🇫🇷, while I'll be at #ESEB2025 in Barcelona 🇪🇸. If you're around, come say hi - always happy to chat about genomics!

📅 The day is today! #SMBE2025 in Beijing starts now, as the registration desk opens to all participants Join us for five days full of the latest discoveries in molecular biology and evolution 🧬 We hope all attendees enjoy the many opportunities for discussion and networking

📢Our #SMBE 2025 Symposium (No. 3) on Experimental Evolution will be held today (7.22, Tuesday) at 10:30 in  Room 4, Building No. 8. An associated poster session will be held at 14:00 (poster number: S3-P01~P16). Welcome to join! let's study evolution in action! 🥳 Society for Molecular Biology and Evolution

Super honored to have chance to co-organize the #SMBE2025 Symposium on Experimental Evolution, together with Jing Li (李婧) & Dao-Qiong Zheng. Thank Dmitri Petrov for serving as our invited speaker. Also thank all the oral/poster presenters and audience. Society for Molecular Biology and Evolution

谢谢北京！ What more is there to say? A last morning round-up by a great talk by Qiaomei Fu on the evolution of East Asian human population, and a beautiful closing ceremony with credit where credit is due - established and upcoming researchers, volunteers, organizers.

First #SMBE meeting for our lab！Definitely a memorable experience. Already looking forward to the next one! Society for Molecular Biology and Evolution #SMBE2025

It is great to have Dmitri Petrov here at Sun Yat-sen University Cancer Center to give us an highly inspiring talk on “Fitness landscape of tumor suppressor genes in lung cancer ”. Tour de force experiments, mind blowing results, and exciting bench-to-bed perspectives!

Longdust, a new tool to identify highly repetitive STRs, VNTRs, satellite DNA and other low-complexity regions (LCRs). Similar to SDUST but for long regions. github.com/lh3/longdust