Excited to share our work Cell Metabolism: What happens when sick neurons dump fat to glia? We saw it by eye using Lingyan Shi 🔬 authors.elsevier.com/a/1izph5WXUlWj… Congratulations to all the authors and our wonderful collaborators!🙌

Collaborating with Dr. Xu Chen Xu Chen, PhD Dr. Yajuan Li, MD PhD imaged brain microglial lipid droplets accumulation under tauopathy condition with DO-SRS, which is further proof that newly synthesized lipid droplets plays an important role in brain cell energetics, echoing

Hi all, what is happening to foreign scientists in Florida is horrible. Pls Join and donate to AAPI orgs in Florida to help us sustain recruiting amazing scientists from Asia to America. As we have seen with RvW, this mentality can easily spread across the country.

The Program in Immunology congratulates Professors Sue Kaech Kaechlab (Sue Kaech) and Steve Hedrick on their election to the National Academy of Sciences! nasonline.org/news-and-multi… Salk Institute UCSD BioSciences

P66 is a bacterial mimic of CD47 that binds the anti-phagocytic receptor SIRPα and facilitates macrophage evasion by Borrelia burgdorferi biorxiv.org/content/10.110…

THEMIS promotes T cell development and maintenance by rising the signaling threshold of the inhibitory receptor BTLA | PNAS pnas.org/doi/10.1073/pn…

#NewIssue On the cover: In this issue of Cell Metabolism, Li et al. reveal that sick neurons release lipids to the glia, causing lipid droplet accumulation and neuroinflammation. The artwork, inspired by Van Gogh's Starry Night, depicts a brain with lipid droplets. Artwork by

The best department to thrive in ♥️♥️♥️ APPLY APPLY APPLY!!!

🔬 Are you eager to dive into the world of light microscopy and learn from top-notch microscopists about its essential techniques for life science applications? If that sounds exciting, don’t miss out on this free, in-depth iBiology series! 👉 ibiology.org/online-biology…

Excited to share our work, new in Science Magazine: science.org/doi/10.1126/sc…. We explored how sex chromosomes, gonadal hormones, and their interaction shape cellular responses in aging and #Alzheimers mouse models. This led to key insights on Tlr7 and neurodegeneration 🧵(1/5)

Delighted to share our new preprint on the cell biology and genome of Stentor pyriformis, a giant ciliate that maintains Chlorella endosymbionts in surface-associated microtubule baskets. biorxiv.org/content/10.110…

A highly conserved motif in human PD-1 but absent in rodent PD-1 is linked to differential inhibitory activity Science Immunology Enfu Hui Jack Bui science.org/doi/10.1126/sc…

Today in Science Immunology: Much of our knowledge of PD-1, a leading cancer target, comes from studies in mice. UC San Diego researchers found that PD-1 in mice is much weaker than the human version, providing new information for future cancer treatments. go.ucsd.edu/40ihXix

Excited to share our latest paper describing the functional divergence of PD-1 across species. Thank you for Enfu Hui for the invaluable guidance, and Jack Bui Zhengting Zou ChuanWu_Lab et al. for wonderful collaboration! science.org/doi/epdf/10.11… today.ucsd.edu/story/scientis….

Our work by Anna Huhn Anna Huhn is now published Nature Communications ! nature.com/articles/s4146… We show that the antigen contributes to the overall reach of the antibody, and that this molecular reach determines antibody function. Thank you to the reviewers for constructive feedback!

Scientists have identified functional differences between human and mouse #PD1, which could impact preclinical research on cancer #immunotherapies. Enfu Hui Jack Bui UC San Diego Learn more in Science #Immunology: scim.ag/4a1KHzq

663 days since the senseless tragedy that took An, we present a manuscript that reports some of the discoveries that she left us. biorxiv.org/content/10.110…

The Program in Immunology welcomes Dr. Joseph Sun Joseph Sun Lab from Memorial Sloan Kettering Cancer Center and Weill Cornell Medicine. Please join us for his seminar on Wednesday February 5!