Chaperones are TRENDy! Our new review on the specific molecules that target TRAP1 as promising leads for drawing innovative therapeutic strategies tinyurl.com/pcytb2ww Trends in Pharmacological Sciences Rasolab Elisabetta Moroni CNR - SCITEC The Colombo Lab Carlos Sanchez Hsp90 Chaperone Machine The Chaperone Code

📢In recognition of his fundamental contributions to #ProteinStructure formation and the role of #chaperones, Prof. Johannes Buchner BuchnerLab TU München will be awarded the #OttoWarburgMedal 2024 of the GBM and its sponsors Elsevier and BBA🏅Congrats🎉

Our next Hsp90 webinar is on Monday Dec4, with Marco Prado 🌻 presenting on the Hsp90 chaperone machinery in neurodegenerative diseases. 12pm EST/6pm CET. Excited to hear this talk🌟Find out more on hsp90.org

Hsp70-Hsp90 complex seen in the wild today at UNC Charlotte 🔥🔥🔥 UNC Charlotte UNC Charlotte Biological Sciences with van Oosten-Hawle lab #chaperones #proteostasis #hsp70 #hsp90

I love it!!! Now all we need is some Co-chaperones🤣🤣

I love it!! You two have inspired me!!!

📢 The Call for Applications for our 2024 Early Career Fellowships is now OPEN! If you're a woman scientist in a developing country, don't miss this opportunity for funding that lets you do your own research, without leaving home. All info @ bit.ly/OWSDEC2024

Join us for tomorrow’s Hsp90 webinar! John Catravas: Hsp90 inhibitors in pre-clinical models of acute and chronic pulmonary pathologies. hsp90.org

💥 Happy to announce new publication on Hsp90/Hsp70 complexes! Great work from The Colombo Lab and collab with sofia oliveira! How distinct ligand-states lead to unique functional profiles at different chaperone folding stages. #compchem #chaperone #HSP90 onlinelibrary.wiley.com/doi/full/10.10…

Ever wonder how too much or too little #sugar leads to #disease? communities.springernature.com/posts/unraveli… mdpi.com/2693292 MDPI from Chiosis Lab Memorial Sloan Kettering Cancer Center The Colombo Lab #Research #HealthScience #Covid_19 #Cancer #Neurology

The HSP90 chaperone code regulates the crosstalk between proteostasis and autophagy tandfonline.com/doi/full/10.10…

Congrats to Yaa Amankwah Andrea Kravats and co-authors for uncovering important structural transitions in the chaperone activities of Grp94 (aka gp96, endoplasmin, ERp99, Hsp90b1). Honored to play a small role here. doi.org/10.1073/pnas.2…

Yay, so happy to see this out! Congratulations on a beautiful, thorough mechanistic study, Andrea Kravats Yaa Amankwah and team 👏🏽👏🏽👏🏽

Congratulations to a fantastic Upstate Urology SUNY Upstate Urology Residency resident Dr Nathan Nahhas on an excellent presentation of results from his research rotation in my lab at Upstate Research Upstate Medical University Beyond the Doctorate Day!

Elegant study by Derbyshire Lab @ Duke and Haystead Lab on selective targeting Hsp90 in Malaria! cell.com/cell-chemical-…

Can computation help understand biology? We discuss it in this paper. Elsevier Biomedchem Current Opinion/Research in Structural Biology Università di Pavia #compchem #machinelearning #drugdesign Structures, dynamics, complexes, and functions: From classic computati... sciencedirect.com/science/articl…

Check out our new review from our lab (Gianna Mochi and others) on the regulation of mitochondrial chaperone function The Chaperone Code Hsp90 Chaperone Machine in Cell Stress Society International! doi.org/10.1016/j.cstr…

Excited to see this out having contributed to the work with @TroemelEmily lab! It expands on our previous paper PLOS Biology showing that knockdown of Hsp90 in the intestine promotes thermotolerance #Hsp90

Fantastic meeting -- thanks CNIO Stop Cancer (and Paul Workman, Frydman Lab, Gabriela Chiosis, Nabil Djouder, & Llorca lab) for the invitation & hospitality, and to everyone for the great science!

Congratulations to PhD Candidate Gianna Mochi on acing her qualifying exam today!