Hossein Borghaei, DO (@hosseinborghaei) 's Twitter Profile
Hossein Borghaei, DO

@hosseinborghaei

Chief of Thoracic Medical Oncology and Director of Lung Cancer Risk Assessment at Fox Chase Cancer Center

ID: 2804071752

linkhttp://www.fccc.edu/physicians/team/med-onc/borghaei.html?keyword=borghaei calendar_today11-09-2014 18:13:34

1,1K Tweet

5,5K Followers

796 Following

Hossein Borghaei, DO (@hosseinborghaei) 's Twitter Profile Photo

Love to see my “former” fellows, current colleagues and friends at ASCO. So happy to see them being so successful.#ASCO, #FoxChaseCancer ⁦Fox Chase Cancer Center

Love to see my “former” fellows, current colleagues and friends at ASCO. So happy to see them being so successful.#ASCO, #FoxChaseCancer ⁦<a href="/FoxChaseCancer/">Fox Chase Cancer Center</a>⁩
Giannis Mountzios (@g_mountzios) 's Twitter Profile Photo

Being part of a history-making drug that helps pts with #SCLC live longer and better is the biggest reward a thoracic oncologist could hope for. Grateful being involved and to our pts Just out in NEJM Presentation today by 1@only Charlie Rudin #ASCO25

Being part of a history-making drug that helps pts with #SCLC live longer and better is the biggest reward a thoracic oncologist could hope for.
Grateful being involved and to our  pts
Just out in <a href="/NEJM/">NEJM</a>
 Presentation today by 1@only <a href="/charlesrudin/">Charlie Rudin</a> 
#ASCO25
Dr Riyaz Shah (@drriyazshah) 's Twitter Profile Photo

Temab-A; n=41 EGFR ; widespread activity with met exp and other mutations. I’m not sure 15% discontinuation rate due to gd3 or greater tox is that manageable? #ASCO25

Temab-A; n=41 EGFR ; widespread activity with met exp and other mutations. I’m not sure 15% discontinuation rate due to gd3 or greater tox is that manageable? #ASCO25
Jordi Remon (@jordiremon) 's Twitter Profile Photo

ABBV-400 a new antiMET ADC tested in pretreated EGFRm NSCLC reported ORR 26% and DoR 9.8 regardless cMET expression. It is a crowded space with BL-B01D1, DB-1310, dual TKI EGFR/ET etc. Can we ⬆️ ABBV-400 combining with osimertinib?TelisoV + Osi > Teliso alone in mEGFR 🫁#ASCO25

ABBV-400 a new antiMET ADC tested in pretreated EGFRm NSCLC reported ORR 26% and DoR 9.8 regardless cMET expression. It is a crowded space with BL-B01D1, DB-1310, dual TKI EGFR/ET etc. Can we ⬆️ ABBV-400 combining with osimertinib?TelisoV + Osi &gt; Teliso alone in mEGFR 🫁#ASCO25
Stephen V Liu, MD (@stephenvliu) 's Twitter Profile Photo

Telisotuzumab adizutecan (ABBV-400, Temab-A) in #EGFR NSCLC at #ASCO25. This is a cMET ADC like Teliso-V but with a topoisomerase 1 inhibitor. Safety notable for myelosuppression, 7% pneumonitis (1 fatal). RR 63%, DOR 9.8m, PFS 10.9m.

Telisotuzumab adizutecan (ABBV-400, Temab-A) in #EGFR NSCLC at #ASCO25. This is a cMET ADC like Teliso-V but with a topoisomerase 1 inhibitor. Safety notable for myelosuppression, 7% pneumonitis (1 fatal). RR 63%, DOR 9.8m, PFS 10.9m.
Hossein Borghaei, DO (@hosseinborghaei) 's Twitter Profile Photo

Proud to see Dr Padda presenting the results of the S1900E. This is yet another example of how we can all come together and conduct national trials in rare subtypes of NSCLC and answer important questions quickly. #lungmap , #ASCO , #FoxChaseCancer

Proud to see Dr Padda presenting the results of the S1900E. This is yet another example of how we can all come together and conduct national trials in rare subtypes of NSCLC and answer important questions quickly. #lungmap , #ASCO , #FoxChaseCancer
Rami Manochakian MD, FASCO Cancer Education (@rmanochakian) 's Twitter Profile Photo

🔥🚨OncoAlert Hot Off The Press Just published The Lancet In conjunction with presentation ASCO #ASCO25 ✅Results of #IMforte trial of: #Lurbinectedin + #Atezolizumab as 1st line #Maintenance Tx in #Patients with #ExtensiveStage #SmallCell #LungCancer. 👇🏻

🔥🚨<a href="/OncoAlert/">OncoAlert</a> Hot Off The Press

Just published <a href="/TheLancet/">The Lancet</a> 
In conjunction with presentation <a href="/ASCO/">ASCO</a> #ASCO25 

✅Results of #IMforte trial of:

#Lurbinectedin + #Atezolizumab as 1st line #Maintenance Tx in #Patients  
with #ExtensiveStage #SmallCell #LungCancer. 

👇🏻
Stephen V Liu, MD (@stephenvliu) 's Twitter Profile Photo

#ASCO25 Dr. Charlie Rudin presents interim analysis of DeLLphi-304: randomized phase II study of tarlatamab (DLL3 TCE) vs 2L chemo in #SCLC. Chemo was mostly topotecan; 45% of pts were platinum resistant. Clear OS benefit with HR 0.60 (13.6m vs 8.3m). PFS 4.2 vs 3.7m, HR 0.71.

#ASCO25 Dr. <a href="/charlesrudin/">Charlie Rudin</a> presents interim analysis of DeLLphi-304: randomized phase II study of tarlatamab (DLL3 TCE) vs 2L chemo in #SCLC. Chemo was mostly topotecan; 45% of pts were platinum resistant. Clear OS benefit with HR 0.60 (13.6m vs 8.3m). PFS 4.2 vs 3.7m, HR 0.71.
Giannis Mountzios (@g_mountzios) 's Twitter Profile Photo

#ASCO25 After 30 years of failed trials, #tarlatamab changes SoC for our pts with relapsed #SCLC : ✅ mOS: 13.6 vs 8.3 months, HR=0.6, p<0.001 ✅ improved QoL (dyspnea and cough) ✅ 27% vs 62% G3 TRAEs Grateful to all collaborators, Amgen 🧪🔬🧬 science team and above all our pts

#ASCO25 After 30 years of failed trials, #tarlatamab changes SoC for our pts with relapsed #SCLC :

✅ mOS: 13.6 vs 8.3 months, HR=0.6, p&lt;0.001
✅  improved QoL (dyspnea and cough)
✅  27% vs 62% G3 TRAEs

Grateful to all collaborators, <a href="/Amgen/">Amgen 🧪🔬🧬</a>  science team and above all our pts
Dr. Nagla Abdel Karim (@naglaakarimmd) 's Twitter Profile Photo

It was a great pleasure to witness the signing of collaboration between the Egyptian Cancer Society #ECS and The American Cancer Society ⁦ASCO⁩ #ASCO25 I was a member of #ECS since 1995 folowed by 20 years of membership at ASCO. Happy to be part of it.

It was a great pleasure to witness the signing of collaboration between the Egyptian Cancer Society #ECS and The American Cancer Society ⁦<a href="/ASCO/">ASCO</a>⁩ #ASCO25 I was a member of #ECS since 1995 folowed by 20 years of membership at ASCO. Happy to be part of it.
Benjamin Besse (@benjaminbessemd) 's Twitter Profile Photo

Hossein Borghaei, DO Stephen V Liu, MD My main question concerns the long half-life of IO: perhaps the timing of the first dose (D1C1) is what truly matters, since IO concentrations remain high even at three weeks, making subsequent dosing less sensitive to timing.

Alexander Kutikov MD (@uretericbud) 's Twitter Profile Photo

The new exhibit in the lobby of Fox Chase Cancer Center is terrific — from the discovery of the Philadelphia Chromosome to the two-hit hypothesis to Nobel Prize-winning breakthroughs, it honors a legacy that absolutely redefined cancer care. Built on this foundation, FCCC continues to

The new exhibit in the lobby of <a href="/FoxChaseCancer/">Fox Chase Cancer Center</a> is terrific — from the discovery of the Philadelphia Chromosome to the two-hit hypothesis to Nobel Prize-winning breakthroughs, it honors a legacy that absolutely redefined cancer care. Built on this foundation, FCCC continues to