Irina Bezsonova FASEB michele pagano Joazeiro Lab Emilie Korchak Nancy Jaiswal Monika chandravanshi Hitendra & Vasty from NCI Center for Cancer Research added here highlighting their findings!

💥New preprint. We use in-cell crosslinking MS and cofractionation MS to discover novel interactions in Bacillus subtilis. We then model these and all other previously reported interactions with AlphaFold-multimer. biorxiv.org/content/10.110…

Seminal #ubiquitin paper from #40yearsEMBOJ: Cecile Pickart and colleagues defined tetra-ubiquitin chains as minimum requirement for proteasomal recognition doi.org/10.1093/emboj/… embopress.org/page/journal/1…

It was great writing this Perspective with my man Dan Squair on the new world of non-lysine ubiquitination. Exciting times! nature.com/articles/s4158… nature.com/articles/s4158…

Today in partnership with EMBL-EBI, we’re releasing predicted structures for nearly all catalogued proteins known to science, which will expand the #AlphaFold database by over 200x - from nearly 1 million to 200+ million structures: dpmd.ai/AF-22-TW 1/

Very happy to see our latest work published. We correct a misconception that human UFSP1 is a pseudo or dead protease & show its an active UFM1-protease that activates UFMylation #ubiquitin #UBL

Take a minute and read this interview with David Baker. "The possibilities are way beyond anything that any of us can imagine now" english.elpais.com/science-tech/2…

E6AP AZUL interaction with UBQLN1/2 in cells, condensates, and an AlphaFold-NMR integrated structure dlvr.it/Sm5pqM

Congratulations Dr. Srishti Baid!!! Fantastic (and incredibly energetic) dissertation defense - on to post-doc at University of Michigan with David Ginsburg - so very proud of her!! ⁦KU Biology⁩ ⁦Eileen Hotze⁩ ⁦KU Molecular Biosciences⁩ ⁦Dr. Dyan Morgan⁩ ⁦Srishti Baid, Ph.D.⁩

Extremely happy in sharing our work uncovering atypical roles of plant specific RNA polymerase IV. Indeed an enjoyable and exhilarating work with Shiva prasad and others. Available in Genome Research : doi.org/10.1101/gr.277… National Centre for Biological Sciences TIFR India

52 of us Black science faculty came together to discuss Juneteenth and how we can use this holiday to reflect on the ongoing barriers Black scientists face and how we can come together as a biomedical enterprise to tackle these challenges. cell.com/cell/fulltext/…

Welcome to the LSI's newest postdoctoral researcher! In the Ginsburg lab, Srishti Baid (Srishti Baid, Ph.D.) will investigate the mechanisms that allow proteins to travel within cells, and how changes in this cellular transportation can affect cardiovascular disease. #FellowsFriday

When #ubiquitin meets🐣 NIDCR @NIH: check out our inspiring collaboration with @kerosuoLab, revealing how early brain, craniofacial and skin development are coordinated by a monoubiquitylation-based switch. Now out Nature Communications at rdcu.be/dhN90 Thank you to the team!

Disease-specific tau filaments assemble via polymorphic intermediates. This is what had me so excited for the past few weeks! The amazing Sofia Lövestam has solved another 163 #cryoEM structures! 🥳🥳🥳A #tweetorial below. As always, with Michel Goedert. biorxiv.org/cgi/content/sh…

How do different mutations in #UBA1 cause autoinflammatory #VEXAS syndrome, spinal muscular atrophy #SMA, or lung cancer in never smokers #LCINS? Check out our new study with David Beck @NYU, Kylie Walters (she/her) and The Samara Lab now online at The EMBO Journal doi.org/10.1038/s44318…

First paper from our lab! Congratulations to Abbie Collette and co-authors for taking a small project on a mucin O-glycosyltransferase and transforming it into a complex and beautiful enzyme mechanism story. #glycotime science.org/doi/full/10.11…

NMR enthusiasts interested in managing a biomolecular NMR facility: please consider applying your NMR talent to our NCI mission to beat cancer!! linkedin.com/jobs/view/3938…

The first report eLife - the journal by Hitendra and Aravind Ravichandran suggests that besides marking, Fat10 also makes the target protein flexible, causing it to break down effectively. 2/4

Our review paper is out and I am excited to share it! 😄 UMLifeSciences