Congratulations to Jose Campos (Sarah Henrickson) & Franklin Staback Rodríguez, PhD 🇵🇷🇻🇪🔬🦠 (Dr. Janis Burkhardt), named 2022 HHMI #GilliamFellows in recognition & support of their commitment to advancing science through inclusion & diversity!🎉 Penn IGG @IDEAL_Research Penn INSPIRE bit.ly/3viKa91

Move day! Celebrating 3 years of our lab by moving 70 feet down the hall to a beautiful space where we will continue working as a team to better understand mechanisms of CD8 T cell dysfunction in chronic inflammation & inborn errors of immunity. Definitely more fun with windows!

Congrats to the team esp Allen Institute for immunology (Claire, Zach, Pete) and Penn Sarah Henrickson Laura Vella E. John Wherry on this multi-omic human T cell dataset w/TEAseq, deep dive into naive T cells across age. Really fun collab, lots of data to mine.

So proud of post-doc Andrea Mauracher after two great STAT1 focused talks in three hours at #ESID2022! Day 2 of a fantastic meeting is underway—it’s wonderful to see so many friends and colleagues in person.

Between fantastic talks tomorrow, join Peyton Conrey at her fascinating poster delving into the impact of amplified mTOR activation on CD8 T cell function at #ESID2022!

Congrats!

So great to find another group excited about type 2 immunity and CD8 T cell exhaustion! Thanks for visiting our Penn&CHOP community Mika Pennanen!

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Welcome to Penn!

Time to explore a new place to learn and discuss, so I’m heading to Mastodon. I hope to continue our conversations there!

Science Immunology Sarah Henrickson So excited for this story on IgA deficiency to be out at Science Immunology ! Great collaboration with Sarah Henrickson. We were curious why most kids with IgA deficiency were not symptomatic. What exactly is IgA doing for the mucosal and systemic immunity? dx.doi.org/10.1126/sciimm…

In Science Immunology, Children's Hospital researchers provide new model for understanding the most common primary #immunedeficiency in children, Selective IgA deficiency. ms.spr.ly/6013gjhZ1 Image: ©2023 Children's Hospital of Philadelphia. All rights reserved. Illustr. B. Bennett.

Thanks John! There’s definitely more to do, from further defining how absent gut IgA dysregulates immune cell activation and cytokine levels to understanding which patients will become symptomatic and how to predict and prevent it. #ImmuneHealth at CHOP Research and Institute for Immunology and Immune Health (I3H)!

In a new Science Immunology study, our researchers have shown that IgA acts as a “tuner” that regulates the number of microbes the body sees every day. This may explain why some patients with IgA deficiency have symptoms, while others do not. Read more below. ms.spr.ly/6013g5vCv

Why do some people have strong immunity after vaccination and others don't? Join our team as a post-doc to study this! tinyurl.com/nyuPostdoc and teamtfh.org for more. Please RT! #immunology #postdoc

In vitro models of CD8 T cell exhaustion make high-throughput interrogation easy, but can they be used to discover real Tex biology with therapeutic relevance? Read to find out! In our new work from the E. John Wherry lab, out now at Science Immunology, we... bit.ly/45yOFMB

Very proud PI! Great job Jose Campos

Thanks, I had a great time joining @UPenn_Allergy to discuss the role of genetics in our field!

So excited that our paper on preTCRa is out! It was a wonderful experience working with this collaborative, international immunology research team. This story emphasizes how much we can learn from our rare patients—both about new diseases and basic immune mechanisms.