At times like these, reading the Telegraph vs reading the Guardian feels like the difference between night and day

Out now in 📖 Editorial team - Neuroimage Clinical NeuroImage: Clinical, our systematic review of fMRI eating behaviour in obesity surgery. A deep dive into data & resource for neuroimaging 🧠🍩🥗 bariatric communities doi.org/10.1016/j.nicl… Imperial Psychiatry Imperial Department of Brain Sciences Imperial Medicine NIHR Imperial BRC NIHR Imperial Clinical Research Facility

In our recent paper in Cell Metabolism @jananerahbani and no-twitter Jakub Bunk demonstrate that thermogenic adipocytes utilize non-paralogous protein redundancy—through UCP1 and CKB—to promote cold-induced energy dissipation. authors.elsevier.com/a/1iUBU5WXUlWj… Rosalind & Morris Goodman Cancer Institute Thread below:

I find that the joy of science is not strictly derived from gaining an understanding of the intricacies of a complex natural system, but rather from an appreciation of its inherent beauty. Quote of mine as a wide eyed student back in 2010 that I still very much stand by

Dear All, In May there will be an interesting lipid meeting in Warsaw. I hope to see some of you there! conference.nencki.edu.pl/#about

Narcissistic leaders are threatened by talent. They want to be the smartest person in the room. Humble leaders are drawn to talent. They surround themselves with people who make them smarter. Great leaders grow talent. They strive to make everyone in the room smarter.

Bit random I know, but I think I've finally settled on my fave 5 films of all time. They are in no particular order: The Fisher King, Anatomy of a Murder, Carlito's Way, The Wind and the Lion and Remains of the Day. Hitchcock's 'Rebecca' just misses out as does 'The Missing'

This will be a fun meeting - applications are open now.

A diabetes drug related to the latest generation of obesity drugs can slow the development of the symptoms of Parkinson’s disease go.nature.com/49w3aCA

Central inhibition of HDAC6 re-sensitizes leptin signaling during obesity to induce profound weight loss dlvr.it/T57GQs

linkedin.com/posts/imperial… Very heartening to see this initiative from my Alma Mater for talented Lebanese students from disadvantaged backgrounds. My time at Imperial was priceless so I highly recommend giving it a go!

A pioneering ‘connectomics’ collaboration has successfully reconstructed one cubic millimetre of brain tissue, but researchers are still just scratching the surface of the complexity it contains go.nature.com/3Q4sSH8

RESEARCH | @DavidFinlayTCD, Lydia Lynch et al. (Trinity College Dublin): #Metformin treatment is associated with acute increases in the appetite-suppressing metabolite Lac-Phe in several human studies. nature.com/articles/s4225…

RESEARCH |Shuke Xiao 肖舒克, Long Lab et al. (Stanford Pathology): #Metformin triggers production & release of Lac-Phe from the gut, which is required for its effects on food intake & weight loss. ⚕️💊 nature.com/articles/s4225…

What do you get when you combine an NMDA receptor antagonist with a GLP-1 receptor agonist? A molecule that beats the best weight loss drug on the market! nature.com/articles/s4158… Hypothesis-led research lives on! Makes me wonder how an AMPA receptor antagonist would fare?

Mohammed Hankir Thank you Mohammed Hankir. Recently we evaluated the anti-obesity potential of targeting proteins that directly interact with NMDA and AMPA receptors, and found that interfering with AMPA-R (via PICK1) can promote weight loss in rodents Science Advances science.org/doi/10.1126/sc…

It's official, I will be an Assistant Professor in Biochemistry at Trinity College Dublin from Sep :) For those with similar aspirations, it might be a long road getting there which at times feels impossibly steep, but just keep on going and let your love of science guide you

#NewIssue On the cover: In this issue of Cell Metabolism, Li et al. reveal that sick neurons release lipids to the glia, causing lipid droplet accumulation and neuroinflammation. The artwork, inspired by Van Gogh's Starry Night, depicts a brain with lipid droplets. Artwork by

School of Medicine is arguably the World’s best place to be a female scientist, scooping 8 HRB Investigator-Led Projects Trinity College Dublin. Read about the ground breaking studies in Rheumatoid Arthritis, TB, cancer, cerebral palsy & multimorbidity in older adults tinyurl.com/4rppctb6

The discovery of a pathway that controls appetite and calorie burning has led to the development of a drug that modulates both by targeting one receptor, offering a promising strategy for weight loss and improved metabolic health go.nature.com/3Z5rtoW