Grimmlab (@grimmlab) 's Twitter Profile
Grimmlab

@grimmlab

Research team at Heidelberg University (Germany) focusing on next-gen AAV & bocavirus vectors for human gene therapy #AAV #genetherapy #biotech #biotechnology

ID: 1355541308476166145

linkhttps://grimm-labs.com/ calendar_today30-01-2021 15:41:19

102 Tweet

362 Followers

438 Following

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Congrats to Marco Thürkauf (1st author), Randall Platt (Randall Platt), Markus Ruegg (Rüegg Lab) and all co-authors that this paper, which showcases the potential of our AAVMYO vector for in vivo gene knockouts, is now out in Nature Communications: (nature.com/articles/s4146…) #AAV

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Happy that our joint article with Ulrike Protzer's lab (Protzer_Lab) on the use of AAV vectors for development of HBV mouse models is now out: pubmed.ncbi.nlm.nih.gov/39044087/ Congrats to 1st author Lisa Schiller, our former MSc student & now PhD student in the Protzer lab 🎊🥂 #AAV #HBV

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Thank you very much to Richard Horgan (Rich Horgan, 2nd from the right) & Ahna Gavrelos (right) from "Cure Rare Disease" (CRD, Cure Rare Disease) for their visit to our lab, a great talk by Rich at our institute & a fun dinner in the old city 🥗🍖🥨🍻 Please support CRD 💪 ! #AAV

Thank you very much to Richard Horgan (<a href="/RichHorgan/">Rich Horgan</a>, 2nd from the right) &amp; Ahna Gavrelos (right) from "Cure Rare Disease" (CRD, <a href="/CureRareDisease/">Cure Rare Disease</a>) for their visit to our lab, a great talk by Rich at our institute &amp; a fun dinner in the old city 🥗🍖🥨🍻 Please support CRD 💪 ! #AAV
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Thrilled that our work with Christian Buchholz (Paul-Ehrlich-Institut) & Petr Chlanda (@ChlandaL) on DARPin-modified AAVs for selective ex/in vivo targeting to CD8+ T-cells is now out in Molecular Therapy: pubmed.ncbi.nlm.nih.gov/39113357/ Congrats to 1st author Burak & all co-authors 🙌🎉 #AAV

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Had an absolute blast with the whole lab playing Urban golf in a beautiful sunny area near Heidelberg, followed by après-golf lunch at Neuburg monastery. My heartfelt thanks to each & everyone of you for making this such a fun day & a fantastic team event to remember 🏑☀️🫂🙌🍜🍻

Had an absolute blast with the whole lab playing Urban golf in a beautiful sunny area near Heidelberg, followed by après-golf lunch at Neuburg monastery. My heartfelt thanks to each &amp; everyone of you for making this such a fun day &amp; a fantastic team event to remember 🏑☀️🫂🙌🍜🍻
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Excited that our collab w/ Wibke Bayer (Wibke Bayer) & Matthias Vorgerd on a screen of antibodies against 18 AAV variants is published: frontiersin.org/journals/immun… Congrats to co-authors Ellen Wiedtke, Yumi Sano, Nico Fischer & Lisa Schiller (former) from our lab & all others 🤗 #AAV

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Happy, humbled & honored that our lab is a partner in the new & comprehensive "European Rare Diseases Research Alliance - ERDERA" that unites >170 organizations from 37 countries in our joint ambition to deliver tangible solutions to rare diseases patients around the world 🤲🤝🫂

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The European Rare Diseases Research Alliance ERDERA kicks off with a bold vision to make Europe a global leader in rare diseases research and innovation. 🚀 Read press release🗞️erdera.org/wp-content/upl…​ 🌍💙 #ERDERA #RareDiseases EUScience&Innovation🇪🇺 Horizon Europe🇪🇺 Inserm

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Had a fantastic time at the XIX Parvovirus Workshop in Leuven (Belgium). Thx to Els Henckaerts & her local team - you did great 👍👏 Congrats to our PhD student Yumi Sano whose exciting work on new Bocavirus vectors attracted a lot of attention. More here: parvovirusworkshop2024.org

Had a fantastic time at the XIX Parvovirus Workshop in Leuven (Belgium). Thx to Els Henckaerts &amp; her local team - you did great 👍👏 Congrats to our PhD student Yumi Sano whose exciting work on new Bocavirus vectors attracted a lot of attention. More here: parvovirusworkshop2024.org
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THX to all PhD students & speakers who made our "HBIGS Summer school 2024" on gene therapy such a success & so much fun 🤗☀️🍨🛳️🎳 ! Thx to HBIGS Heidelberg for funding & Revvity for Life Sciences for extra support! Thx @DominikNiopek & Martina Weiss for the co-organization 🙌🫂 #genetherapy #AAV

THX to all PhD students &amp; speakers who made our "HBIGS Summer school 2024" on gene therapy such a success &amp; so much fun 🤗☀️🍨🛳️🎳 ! Thx to <a href="/HBIGS_HD/">HBIGS Heidelberg</a> for funding &amp; <a href="/RevvityLifeSci/">Revvity for Life Sciences</a> for extra support! Thx @DominikNiopek &amp; Martina Weiss for the co-organization 🙌🫂 #genetherapy #AAV
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Happy to see a "Research highlight" article written by our PhD student Jixin Liu published in Signal Transduction and Targeted Therapy: nature.com/articles/s4139… Well done, Jixin, and congratulations 😊👍 !

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Congrats to our 2 brilliant students - Anna Schneider & Lea Heckelmann - who graduated w/ a BSc in Biosciences & w/ top grades (1.0) 🥂👏 Fantastic work on new bocaviral vectors for human gene therapy (Anna) or optimized AAV vectors for antibody expression (Lea) 👍 Uni Heidelberg

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Honored to be a co-author w/ amazing colleagues from Universities Vienna, Stanford, Tübingen & Karolinska Institute on a review on cochlear gene therapy: sciencedirect.com/science/articl… Thx & congrats Lukas, Ellen, Francois, Steffen & Chris 🦻🤗 Christopher R. Cederroth Universität Tübingen Uni Heidelberg #AAV

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Glad that our lab could contribute to 2 AAV papers that have now won the "Paper of the Quarter" award by the German Society of Gene Therapy (DG-GT e.V.) dg-gt.de/paper-of-the-q… Congrats to Jannik Wagner (Klaus Überla lab) & Burak Demircan / Luca Zinser (Christian Buchholz lab) 🥂🎉

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Hats off to the Oliver Müller lab for their RNA-based directed evolution of novel AAV9 capsid variants for potent species-independent gene transfer to cardiomyocytes of mouse, rat or human origin 👍❤️‍🩹 Thx for the great collaboration & joint publication: liebertpub.com/doi/10.1089/hu… 🤝