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Many congratulations to Dr. Abbie Brewer (Abbie Brewer) from Sapkota Lab who successfully defended her PhD thesis today. Thank you Will Farnaby and @FleurMFerguson for examining Abbie's thesis and Greg Findlay for convening. MRC PPU UoD Life Sciences University of Dundee

Congratulations, Greg

Join us! Postdoctoral Research Assistant position available in Sapkota lab ppu.mrc.ac.uk/careers/recrui… Gopal Sapkota Sapkota Lab

We're starting to recruit postdocs to work on this exciting ERC (now UKRI) project. Please get in touch if you would like to join us, or spread the word. #phosphatases #redox #Tcells Europe-SFRR The Lister Institute of Preventive Medicine EMBO YIP

Really proud of these two studies Jin-Feng Zhao and Abbie Brewer! Targeted dephosphorylation by small bivalent molecules is feasible and can rewire signalling! Well done to everyone involved and great collaboration with Kei Sakamoto and Dario Alessi.

Targeted Dephosphorylation In Action!! Two studies by Jin-Feng Zhao and Abbie Brewer from the Sapkota Lab. Excellent collaboration with Kei Sakamoto. cell.com/iscience/fullt… and cell.com/iscience/fullt… MRC PPU University of Dundee UoD Life Sciences

Excited to reveal our new chemical-genetic system to inhibit PP2A-B56 phosphatase. We use this to characterise its substrates and roles during mitosis. This is a simple yet powerful approach to inhibit any enzyme/protein relying on SLiM-based interactions biorxiv.org/content/10.110…

New discovery by Sapkota Lab and Barcelona Clinical Team sheds light on rare skin disorder mechanism ppu.mrc.ac.uk/news/new-disco… #palmoplantar #PalmoplantarKeratoderma #PPK

New paper (royalsocietypublishing.org/doi/10.1098/rs…) by Sapkota Lab PhD student Lorraine Glennie establishes the molecular basis for pathogenesis of PKP caused by a novel mutation in FAM83G. Excellent collaboration with clinical team led by Amaia Lasa-Aranzasti from Vall d'Hebron.

Excited to kick off our post-summer series! This Thursday we are hosting Gopal Sapkota sharing insights on redirecting phosphatase through induced proximity. **Important: The time has changed to 12 PM EST!

I hope you can join us the the 1st International Conference on CK1 Protein Kinase Family. This is an exciting meeting that brings together a diverse group of scientists working on CK1 family (ck1.conferences-pasteur.org). #CK1 #PARIS

The final work from my PhD The Francis Crick Institute is out today in Open Biology The Royal Society! Using zebrafish, we show that the poorly understood, oncogenesis-related gene Fam83f plays roles in larval hatching and the DNA damage mediated autophagic response. 🐟🧬1/2 royalsocietypublishing.org/doi/10.1098/rs…

Huge thanks to all my co-authors, including @FayFayCooper, @CALM_STP, Gopal Sapkota and of course, my amazing mentor, Jim Smith. As always, thank you to the 🐟and 🐸 that enabled this work, and all my previous colleagues from the Smith lab. 2/2

Many congratulations to Preethi Soundarya Sathyamurthi, who successfully defended her PhD thesis today. Thanks Satpal Virdee and Katrin Rittinger for examining. Proud supervisors Markus Queisser and Gopal Sapkota!! GSK MRC PPU Sapkota Lab

Best of luck today to Lorraine Glennie of the Sapkota lab, defending her PhD thesis 'The Role of Cellular and Protein Context in Targeted Protein Degradation' ppu.mrc.ac.uk/research/lab-m… #Dundee #PhDLife

Congratulations to Ian Ganley from MRC PPU, University of Dundee, the very deserving winner of the 2025 Hooke Medal bscb.org/hooke-medal-wi…

Researchers and people with #Parkinsons connect through talks, tours and poetry ppu.mrc.ac.uk/news/researche…

For those working on the CK1 family of protein kinases, there is an exceptional international conference this July in the beautiful city of Brno in Czech Republic. Only few more days left for registrations!! Link: ck1.sci.muni.cz/?utm_source=ne… Hope to see you there!! #CK1

Renowned filmmakers Herne Katha showcase Sapkota Lab’s research to global Nepali audience ppu.mrc.ac.uk/news/renowned-… Sapkota Lab Herne Katha

🎉 I am thrilled to share that our latest work on is now publicly available on bioRxiv. The title is "Mutations within the predicted fragment-binding region of FAM83G/SACK1G abolish ints interaction with the Ser/Thr kinase CK1α".