I’ll be presenting two of our #immunotherapy for #myeloma projects. One oral presentation on the combination of TIGIT and lenalidomide (Sat 4:45pm) and a poster on an IL-2/IL-15 mimetic (NL201) on Sat as well!

Still time to apply! The Hill lab is looking for a postdoc to work on Immunotherapy/CAR T cell projects. Message me if you have any Q's about working in the lab etc. FHCRC has great visa support as well! social.icims.com/viewjob/pt1638…

Commentary on Albert C. Yeh, MD's paper out today in @BloodJournal! #BMT #hematology

CMV exposure drives long-term CD57+ CD4 memory T-cell inflation following allogeneic stem cell transplant loom.ly/0EL7W_E

Agonist #immunotherapy with engineered IL-18 following allogeneic bone marrow transplant in mice improved anti-tumor activity without increasing the chance of graft-versus-host onset. Fred Hutch Cancer Center Monash University Simone Minnie Hill Lab scim.ag/bY

In new work published in Science Immunology, Drs. Simone Minnie and Geoff Hill show that by directing immune stimulation at the right group of cells, they can prevent #leukemia and #myeloma relapse after #bonemarrowtransplant without exacerbating #GVHD. bit.ly/3TnBTuh

When the autograft team hears the boss has a penchant for band T-shirts….

Next paper out of the Hill Lab!! Regulatory T cells suppress myeloma-specific immunity during autologous stem cell mobilization and transplantation ashpublications.org/blood/article/…

My fave postdoc project is out today!! This manuscript has been a labor of love and I'm so excited to finally share it with the broader immunology community. science.org/doi/10.1126/sc…

Treg depletion during SCM expands polyfunctional effector T cells in mobilized grafts and enhances antimyeloma immunity after ASCT. ow.ly/syjV50RjakL #transplantation #immunobiologyandimmunotherapy

For open access to our recent manuscript describing T cells that retained functional capacity despite a terminally exhausted phenotype, visit the Hill Lab webpage via the link below and scroll down to the myeloma section! research.fredhutch.org/geoff-hill/en/…

New paper out of the lab! We found that calcineurin inhibitors prevented differentiation of exhausted T cells after allogeneic BMT. Rather, these T cells became memory cells and were able to cause chronic GVHD after drug removal. doi.org/10.1172/JCI170…

I’m excited to share what has been 5 years in the making (my first project in the lab starting as a heme/onc fellow)! Microbiota dictate T cell clonal selection to augment graft-vs-host-disease following stem cell transplant. Immunity Hill Lab cell.com/immunity/fullt…

New work out of the lab! Julie Boiko, MD, PhD has identified tractable monocyte gene signatures of IL-17 and CSF1-driven chronic GVHD that can be extended to patients. ashpublications.org/blood/article-… First edition preview out now!

Graft-versus-Host Disease Prophylaxis with Cyclophosphamide and Cyclosporin | New England Journal of Medicine nejm.org/doi/full/10.10…