🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

It is great to see our work published in this issue of Cancer Discovery and commented on by Zev Wainberg in the Spotlight section, discussing the clinical potential of developing WRN inhibitors! aacrjournals.org/cancerdiscover…

From the August issue: Novel WRN Helicase Inhibitors Selectively Target Microsatellite Unstable Cancer Cells. bit.ly/3yN4ip3 Gabriele Picco Mathew Garnett Garnett Lab Wellcome Sanger Institute

Congratulations to Mamta Sharma on being shortlisted for the Outstanding Technician of the Year award! 🎉 Technician Commitment Garnett Lab

Congratulations Lori

📰Read ‘Base editing screens define the genetic landscape of cancer drug resistance mechanisms’ from Wellcome Sanger Institute EMBL-EBI Open Targets Garnett Lab Mathew Garnett Matt Coelho and others in Nature Genetics here ⤵️ nature.com/articles/s4158…

Cancer Research Communications Eva Garnett Lab Sok Ching Cheong 🧬✨ I’m thrilled to share our latest publication on integrative analyses of CRISPR screen and high-throughput drug screening in Oral Squamous Cell Carcinoma (OSCC), is now accepted and available at Cancer Research Communications 🧬✨!

Mapping cancer resistance functional gene variants by #CRISPR genome editing, enabling effective alternative treatments nature.com/articles/s4158… Nature Genetics Matt Coelho Garnett Lab Wellcome Sanger Institute

Delighted to share our work in Nature Genetics using base editing to map genetic mechanisms of drug resistance. If you're interested in drug discovery then check it out. Access here rdcu.be/dXmlo [rdcu.be]. Congratulations to the team and Matt Coelho

Congratulation Annie. Wonderful work and a delightful collaboration.

Just arrived in Barcelona for #ENA2024! Looking forward to presenting our research on MSI cancer cell evolution under selective pressure from WRN inhibitors this Friday afternoon. The beach is just 50 meters away—what a perfect setting for science!

We are hiring a core-funded Group Leader working in Artificial Intelligence! The position comes with a flexible start-up package: 👩‍🔬2 postdocs and a technician 🧑‍🎓2 PhD students 🔬budget for our state-of-the-art core facilities. Come and join us 👉 cruk.cam.ac.uk/careers/group-…

Be WRNed! Gabriele Picco rocking the stage at #ENAsymp24! Amazing work done and more to come!

A protein expression atlas on tissue samples and cell lines from cancer patients provides insights into tumor heterogeneity and dependencies. nature.com/articles/s4301…

Thrilled to share our paper now out nature delineating #plasticity during #CRC #metastasis, a fantastic collaboration led by Andrew Moorman Ellie Benitez, and @f_cambuli from the Karuna Ganesh Lab and @dana_per lab! nature.com/articles/s4158… rdcu.be/dYAVK. A 🧵

We have an open #postdoc position to study the molecular mechanisms of #DNArepair !🧬🔬 The project will build on recent findings nature.com/articles/s4158… and established collaborations, using #cryoEM and #SingleMolecule imaging. Access to fantastic facilities @MRC_LMB .

My old account has disappeared, and I'm not sure why. I’m hoping to recover it somehow or link it to my new one! Thank you to everyone for reconnecting!

Excited to share our new preprint in which we address: (1) Accurate sequencing of sperm at scale (2) Positive selection of spermatogenesis driver mutations across the exome (3) Offspring disease risks from male reproductive aging [1/15] medrxiv.org/content/10.110…

Excited to share our latest work. We introduce an improved version of NanoSeq, a duplex sequencing protocol with <5 errors per billion bp in single DNA molecules, and use it to study the somatic mutation landscape of oral epithelium in >1000 people. 1/n medrxiv.org/content/10.110…

🚨 Very happy to announce the publication of my PhD work Nature Biotechnology where we combined base and prime editing screens to investigate the impact of genetic variants in cancer. 🧵⬇️ nature.com/articles/s4158…

New Gordon Research Conference Alert: Synthetic Lethality Approaches in Oncology. grc.org/synthetic-le.... Join us 20-25th July 2025 for an intimate meeting with thought leaders in the field. Great for networking and opportunities for early career scientists to present.