TLR4+ ILC2 contribute to persistent type 2 immunity in airway diseases through a non-specific immunological memory Nature Communications nature.com/articles/s4146…

Two vaccine candidates using mRNA technology elicit a potent immune response against HIV go.nature.com/45dWl8h

Age-associated defects in #Tcells can disrupt the intestinal barrier and compromise gut immunity in mice, promoting #inflammaging and health decline. Mittelbrunn Lab Learn more in Science #Immunology: scim.ag/477uqtg

Perspective Immunity Immanuel Kwok Lai Guan NG From complexity to consensus: A roadmap for neutrophil classification cell.com/immunity/fullt…

María José Mendoza León defendió con éxito su tesis doctoral en Biociencias Moleculares (UNAB), mostrando que la hipotiroxinemia gestacional afecta la barrera intestinal de la progenie, generando inflamación, disbiosis y mayor riesgo de enfermedad intestinal.

How does Epstein- Barr virus induce multiple sclerosis? The infection leads to B cells that get into the brain, attracting pro-inflammatory T cells (mouse model) nature.com/articles/s4158…

Microbial dysbiosis sculpts a systemic ILC3/IL-17 axis governing lung inflammatory responses and central hematopoiesis - Mucosal Immunology mucosalimmunology.org/article/S1933-…

Antibiotic effects on the gut microbiome across diverse geographies dlvr.it/TMLNNG

Inosine boosts infant antiviral immunity dlvr.it/TMMf2v #immunology

New research in mice provides insight into how #GMCSF regulates conventional dendritic cell (#cDC) subsets in the lungs. Christoph Schneider Learn more in Science #Immunology: scim.ag/45nQ9dV

Two new Science studies in mice reveals that food-induced anaphylaxis is driven by distinct immune pathways involving inflammatory lipids called leukotrienes. The findings point to the potential of the drug Zileuton to block this life-threatening response. 📄:

N&V Nature Immunology Emanuela Pasciuto CD4+ T cells migrate from the gut and adipose tissue to the brain parenchyma, in mouse and human, transmitting information on diet and microbiome to the subfornical organ, altering feeding behavior nature.com/articles/s4159… nature.com/articles/s4158…

REV-ERBα and REV-ERBβ, which control the expression of clock genes, are also central to maintaining ILC3 in a state that facilitates the maintenance of a balanced and healthy intestine Nature Immunology The Colonna Lab nature.com/articles/s4159… preview Arthur Mortha nature.com/articles/s4159…

On the non-immune functions of immune cells 😻Fantastic review! Immune system influence on physiology | Science science.org/doi/10.1126/sc…

A Review in Nature Reviews Gastroenterology & Hepatology discusses how diet shapes the gut microbiome, the role of diet–microbiome interactions on the immune, nervous and cardiometabolic systems, and implications for dietary guidelines and precision nutrition. go.nature.com/41F8baD

Congrats Jazib Uddin! CGRP-related neuropeptide adrenomedullin 2 promotes tissue-protective ILC2 responses and limits intestinal inflammation Nature Immunology nature.com/articles/s4159…

New online! Respiratory viral coinfections: interactions, mechanisms and clinical implications nature.com/articles/s4157…

Chronic alcohol use downregulates small intestinal mAChR4 & reduces GAP formation, disrupting AMP + IL-22 secretion by ILC3 to facilitate microbial translocation to liver, driving disease, which can be reversed by activation of IL6ST/gp130 nature nature.com/articles/s4158…

Feliz de acompañar este nuevo proceso de admisión al Magíster en Biotecnología y Ciencias de la Vida (UNAB). Como Secretario Académico, estoy disponible para resolver dudas o consultas que tengan sobre el programa.

Microbiota metabolite TDCA binds P2Y10 on intestinal ILCs to maintain tissue residency through CD69 and integrin alphaE Science Advances science.org/doi/10.1126/sc…