Potentially massive (positive) implications for US biotech as Trump admin cracks down on US x China transactions. $XBI, naturally, seemed to drop on the Feb 21, 2025 news. Am I missing something?

If you ever feel you’re hopeless because you’re behind your peers, just remember that of the two Culkin kids, the one that won the Oscars wasn’t the one that was the Home Alone star, the most famous kid of our generation; he was the one that was an extra in that movie.

No words.

One's 30s are a crucial period for professional advancement. Especially in so-called "greedy careers": those where returns to longer hours are non-linear. But one's mid 30s is also when most women's fertility starts to drop 🧵 worksinprogress.co/issue/fertilit…

I analyzed 255 comments on Paras Chopra's tweet and here's what people are noticing: - Men's Jewelry - Senior fitness centers - Sabbaticals as a formal industry - Barefoot footwear - Recovery services (sleep, physical, mental) - Quiet luxury essentials - AI health screening -

new blog post with Amy Lu ! we tell the story of how we figured out latent diffusion for all-atom protein co-generation, with our methods CHEAP and PLAID. link 👇

We (Nathan C. Frey and I) wrote a piece on all-atom protein co-generation, and the latent space compression explorations that enabled it 👇 Should be a good tl;dr of for those looking for a latent diffusion model / text-to-protein generation / scaffolding-free metalloenzyme design!

In early Jan 2025 I posted on the rise of Chinese biotech - One quarter later, is it fair to say we have reached “peak China bio outlicensing”? My Jan post came right before a big boom in deals announced the week of JPM (9 out-licensing deals & 5 newco deals announced totaling

A paralysed man can stand on his own after receiving an injection of neural stem cells to treat his spinal cord injury go.nature.com/41ZCoRj

Building a generational VC fund is hard – but preventing heartbreaking diagnoses and extending healthy lifespan is harder (and matters more). We're hiring (Associate, Principal, Partner) to help accelerate longevity science. Interested? Reach out at careers [at] age1 [dot] com

Someone should do a ChatGPT project that parses core claims in papers and then checks how those claims are cited. It’s crazy how truth gets lost in citations. Pick a random paper, follow it 2-3 layers deeper, and you'll find that most of these structures will be built on shaky

Quintin is an exceptional company builder and scientist. He’s someone you meet who immediately leaves a lasting impression. Nudge is a company to watch and it’s great to see some of their work come online.

What US Biotech Can Do to Meet the Moment. By David Li David Li, CEO of SF-based Meliora Therapeutics. timmermanreport.com/2025/04/a-new-…

I fear the US Biotech industry will dramatically shrink in the next 5 years unless we see 180° reversal of regulatory policy from Trump Administration. We're seeing a multi-part dismantling of the biotech industry as we knew it happen in real time. NIH funding cuts reduce

You’ve heard of vibe coding—meet vibe protein design. Click, launch, and watch the binders roll in. That’s what we're unveiling with Ariax Bio today.

I don’t think people realize how dire the threat to American scientific research is. Whole lines of research will end. Life-saving and world-changing discoveries won’t be made. On the course we’re on it could be decades for the engine of American innovation to recover. If ever.

do something that scares you every day. if you do that every day will be scary and your life will be scary in general

hey chatgpt, build me a cure for cancer with 0 tox and pre-empted FDA approval. make no mistakes.

Longevity is an answer to so many of the challenges facing America. → Exploding debt + deficits → Slowing GDP → Declining fertility We go into it in detail here (and details matter here, so it's worth the extra characters). nfx.com/post/longevity… Simplified argument

NEW: The OpenAI-backed biotech startup Chai Discovery announced a new suite of AI models today, called Chai-2 The main result: making de novo antibodies with a 19% hit rate on average, which Zavain Dar called "fucking killer" endpoints.news/openai-backed-…