Kidney immunology from pathophysiology to clinical translation bit.ly/3PWYiPi

Researchers have demonstrated that #CARTcells can transfer tumor-specific receptors to T cells in mice via #trogocytosis, endowing recipient cells with antitumor immunity. @UU_University Read more in Science #Immunology: scim.ag/3CwCE1c

Comparison of the tumor immune microenvironment and checkpoint blockade biomarkers between stage III and IV non-small cell lung cancer [Jul 26, 2022] @YinjieGao et al. Cancer Immunology, Immunotherapy link.springer.com/article/10.100… #ImmunoOnc #lcsm #PrecisionMedicine

A Science #Immunology study from last year describes an antibody-based alternative treatment for B cell non-Hodgkin #lymphoma that boosts #NaturalKillerCell antitumor activity in preclinical models without causing serious toxicities. bit.ly/4fM7bpT #WorldCancerDay

In the latest #SciencePodcast🎙️, Dan Kaplan, a professor in the departments of immunology and dermatology, talks about why it sometimes pays to scratch that itch. 🎧 Listen here: scim.ag/4aFVtf8

New research show that NPs coronas modulate immune response via TLR4/MyD88/NF-κB under inflammatory conditions. These findings could explain therapeutics toxicity and altered efficacy. Learn more: nature.com/articles/s4146… 🌡️

At Queen's University 🇨🇦, Dr. Paul Kubes uncovers how delayed Kupffer cell migration drives immune vulnerability in newborns. This research opens doors for neonatal care. Learn more: queensu.ca/gazette/storie… 🔬

Why does immunotherapy work for some but not others? 🤔 New research highlights the critical role of the immune microenvironment in #AML treatment. 🧪 Full study here: ma-clinique.fr/lenvironnement…

Slowing Type 1 Diabetes before insulin dependence is now possible!🔬By modulating the activity of T cells, beta cells killers, an anti-CD3 antibody protects them and delays the need for insulin. A groundbreaking breakthrough from Sanofi🔗sanofi.com/fr/magazine/no…

A new Uni of Birmingham trial showed promising results for treating patients with #IBD and autoimmune liver disease by utilising a common antibiotic to treat infective diarrhoea, with 80% achieving clinical remission. Full article now online: bit.ly/4aSoGn2

A new Science #Immunology study reveals that #BreakoutLesions in patients with #MultipleMyeloma contain hotspots of tumor-immune cell co-evolution, which could inform future therapeutics. scim.ag/4hMrLHs

🚨 26% relapse after kidney transplant! A study on 137 patients confirms that anti-PLA2R1 antibodies are a key risk factor for relapse. Targeted monitoring is essential 🩺 👏Kudos to Dr. Cremoni and the CHU de Nice team! 🔗 kireports.org/article/S2468-…

#Mitochondrial damage can contribute to #InflammatoryBowelDisease, catch up with the literature with this review online now: mucosalimmunology.org/article/S1933-…

Senior microbiome enhances immunotherapy! 🧬 In people over 60, specific gut bacteria stimulate T cells, boosting the effectiveness of cancer treatments. Toward more powerful immunotherapy? 🔗 biocodexmicrobiotainstitute.com/fr/limmunother…

Type 1 diabetes is rising. Access key resources to: • Improve early screening • Provide mental health support • Reduce misdiagnosis 🔗 Learn more: bit.ly/48ZlwwS #DiabetesCare #Type1Diabetes #HealthCare

Persistent inflammation without a diagnosis? A study highlights the challenges of SAIDs and offers solutions: genetic testing, empirical trials of therapy, and close follow-up and reassurance to manage uncertainty around diagnosis. 🏥 @touchimmunology 🔗touchimmunology.com/rheumatology/j…

🧬 Dendritic cells (cDCs) activate immunity, but their maturation relies on cholesterol. AXL, a regulatory enzyme, blocks this process by restricting cholesterol transport. Inhibiting it could enhance anti-cancer responses. 👉 nature.com/articles/s4159…

How does the gut orchestrate its defense? 🏰 Researchers tracked TRM cells in action: strategic positioning and rapid response, a model for future targeted therapies. Learn more 👉lji.org/news-events/ne… #Immunology

Our B & T cells remember past threats 🦠. Now, Stanford’s AI Mal-ID decodes these immune "fingerprints" to improve autoimmune disease diagnosis! 🔍 med.stanford.edu/news/all-news/…

🧬 ID3 emerges as a key regulator of stem-like T cells, essential for durable immunity against cancer and chronic infections. A major breakthrough in understanding and enhancing immunotherapeutic strategies. 👉science.org/doi/10.1126/sc…