Tweetorial by Elgin on his recent paper that I tweeted about a few days ago. Please enjoy the awesome movies!

PhDs and Postdocs: we are still accepting abstracts for the GRS on Signaling from Adhesion Receptors - we will be extending the deadline internally for abstract submission until 4/20! Please RT to spread the word! grc.org/signaling-by-a…

New paper! tinyurl.com/459753ww This surprising finding suggests one way by which the cell generates stable linkages between the membrane and cytoskeleton while still allowing rapid cytoskeletal remodeling. Congrats Elgin Korkmazhan!

New paper! Amy Wang describes the probable mechanism by which alpha-catenin, and likely related proteins, makes a force-sensitive catch bond with F-actin. Also, intriguing clues about the origins of cooperative actin binding. Congrats Amy! elifesciences.org/articles/80130

Thanks to some good funding news, the lab is looking for postdocs for projects with @LabSkiniotis and Bill Weis (Stanford Struct. Bio.). We'll be exploring ideas I'm quite excited about at the interface of biophysics, cell, and structural biology. Please email for more details!

Excited to share that kate cavanaugh (Weiner Lab ), Jennifer Hill (@DavidGDrubin ) and I are organizing the 2022 edition of the Bay Area Cytoskeleton Symposium!

New paper! Brian Zhong describes a new strategy for visualizing mechanical forces across proteins in cells. We hope this will be a useful tool for everyone interested in mechanobiology and are excited to build upon this work in the future. cell.com/cell-reports-m…

Just out: MBoC special issue on mechanobiology! Many thanks to Matt Welch and co-editors Dennis Discher, Valerie Weaver, @TheYapLab, and Murrell Lab for involving me in this project. molbiolcell.org

New paper! With the The Soh Lab @ Stanford, we show how single-molecule imaging can be used to to suppress background signal in sandwich-type immunoassays. Congrats and thanks to Amani AH, Sharon S. Newman, and steven tan for a great project and collaboration. nature.com/articles/s4146…

#MotorsInQuarantine will feature Amy Wang from Alex Dunn and Mark Dodding. Join us tomorrow to discuss how actin links to cell-cell adhesions and kinesin-1 is folded into the lambda particle when not busy transporting cargo along microtubules. mechanochemistry.org/whatson/MiQ/

New preprint: Brian Zhong shows that pN forces can potentially activate latrophilin 3, an adhesion GPCR that regulates synaptic plasticity. A first step for the lab in understanding this fascinating class of signaling proteins. Congrats Brian! t.ly/ETL_

We micropatterned lymphocytes on EM grids to facilitate cryo-FIB & cryo-ET, revealing networks of filaments on the Jurkat cell surface. Was awesome to work with Stefan Oliver on this side project during my postdoc in Alex Dunn! #teamtomo Alvéole biorxiv.org/content/10.110…

New paper! Christina Hueschen presents a mathematical model of flocking on arbitrary 2D surfaces. In addition to your favorite creature, the model can be applied to a broad range of problems in active matter physics, e.g. cytoskeletal flows in living cells. journals.aps.org/pre/abstract/1…

Hi Folks, I don't plan on maintaining this account, but I'll leave it up for now. Instead, please consider joining us on Bluesky: @dunnlab.bsky.social