Very excited to have this project wrapped up and in print! Thanks to everyone who helped work on it over the years! James Papatzimas Darren Derksen Ben, Evgueni, and the Bahlis and Hollenberg labs

Back in Canada after helping set up Natasha Garner for her new job in Switzerland. I can’t overstate how much I was impressed by the beauty and of course the food of Switzerland during my first trip across the Atlantic! Hopefully be back soon 🇨🇭

This is in my eyes the most important annual paper for students preparing for a job interview in medicinal chemistry (or process chemistry): provides a great overview about representative drug structures, their targets & synthetic routes used. ACS Publications Bio & Med Chem Content pubs.acs.org/doi/10.1021/ac…

As promised we are launching the Dave Evans Problem Set Generator. This contains all of the problems hosted in his original service, with some modernization and streamlining. organicchemistrydata.org/evans/problems/ questions/suggestions: organicdivision.org/contact/

The 10th UK National Retrosynthesis Competition first round molecule is now released! We are excited to see all of your entries! soci.org/events/young-c…

Next up is Darren Derksen! Check out the recent work done by Derksen and colleagues, as featured in our Emerging Investigators Collection: 'Identification of ligand linkage vectors for the development of p300/CBP degraders'👇 pubs.rsc.org/en/content/art… 📍 Dept. of Chemistry

Excited for this new adventure in Waser Group at EPFL 🇨🇭

I’ve been doing this for a while now and N-end rule degradation continues to amaze me 🤯 jbc.org/article/S0021-…

Bis(trifluoromethylated) ethynyl benziodoxoles are useful reagents, yet their synthesis is cumbersome: now Nieves Nieves P. Ramirez , Tobias Tobias Milzarek and Xingyu Xingyu Liu 刘星宇 developed a practical one-pot protocol directly from iodine(I) Chemical Communications pubs.rsc.org/en/content/art…

New member of the EBX family: Acyl-EBXs are so reactive that they need to be generated in situ and react with thiols to give dithioarylacetals: Look at the work of Pierre Palamini , Julien, Mael and Morgane just accepted in OL J Org Chem/Org Lett pubs.acs.org/doi/full/10.10…

From ChemRxiv to J. Am. Chem. Soc. ! The work of Tin V.T. Nguyen, André Bossonnet and Matt on the Photocatalyzed [2σ + 2σ] and [2σ + 2π] Cycloadditions for the Synthesis of Bicyclo[3.1.1]heptanes and 5- or 6-Membered Carbocycles is now out, thread of a long story 1/4 pubs.acs.org/doi/10.1021/ja…

Very excited this final chapter of my PhD work is out in print! What started as a fun observation of some glowing NMR tubes managed to turn into a nice collaborative project

The sign of a great trainee is when they identify unexpected byproducts and then figure out how they were made! Really proud of the team for this work. Great work by Ricky, Duncan Brownsey, @leonieosullivan, Connor, Emily Chang, Ketul Patel (Ph.D.) and Eugene.

What happens when you irradiate carbonyl cyclopropanes with light? The outcome depend on the substrate, but always via a biradical: if you are curious look at the preprint ChemRxiv of Tin Tin V.T. Nguyen André André Bossonnet Duncan Duncan Brownsey and Matt go.shr.lc/3WQAdyb

I am looking to hire a postdoctoral researcher to continue work on a MITACS project in collaboration with a local industry partner. Please repost. Apply through link if you are interested: careers.ucalgary.ca/jobs/14658602-…

Tether chemistry alert: the work of Helena Helena Solé , Mikus Mikus P and Lucas on endo vs exo selective carboamination of propargylic alcohols is now accepted Angewandte Chemie EPFL Chemistry NCCR Catalysis onlinelibrary.wiley.com/doi/10.1002/an…

We have now added the DSC stability data of benziodoxole-type reagents reported by Obermüller, Waser and co-workers in OPRD: pubs.acs.org/doi/10.1021/ac… In the database on our website: epfl.ch/labs/lcso/rese… The data of more than 40 compounds is now available!

I'm not sure how many people are still on this site but I am happy to share our newest collaborative work published in ACS Chem Neursci with Zymedyne and funded by MITACS. Huge thanks to Ketul Patel (Ph.D.) for his hard work on this project! pubs.acs.org/doi/10.1021/ac…

The full studies of Tin Tin V.T. Nguyen, Duncan Duncan Brownsey and André André Bossonnet on the direct photoexcitation of carbonyl cyclopropanes with computation insights from Mat Matthew Wodrich have now been accepted in Angewandte Chemie ! onlinelibrary.wiley.com/doi/10.1002/an…