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You’ve heard of vibe coding—meet vibe protein design. Click, launch, and watch the binders roll in. That’s what we're unveiling with Ariax Bio today.

Startup idea: Bindcraft+validation to design high selectivity binders for all proteins to revolutionize affinity reagents Who is building this?

Patrick Hsu is asking the right question- who is building the future of high-quality, recombinant, structurally-defined binders? You are! When I saw the tweet from ᒍOᕼᗩᑎ ᗪᑌᑕᕼEᑎE yesterday, I started a BindCraft job on Ariax Bio against NLRP3. Anyone want to try these out?

ᒍOᕼᗩᑎ ᗪᑌᑕᕼEᑎE Aaron Ring Patrick Hsu Ariax Bio Yes, ᒍOᕼᗩᑎ ᗪᑌᑕᕼEᑎE — we’re also creating binders eg. for CAR-T; that’s not a problem. However, from a validation perspective, our main focus is on antibodies and nanobodies. At Genotic.com we’ve already validated our own antibodies against ~300 targets using IF, FC,

5th Antibody Validation Meeting. September, 9-11, 2025. University of Bath, UK. A meeting with scientists, industry, and suppliers to discuss best practices and improve research antibody validation. antibodyvalidation.co.uk

More evidence that scRNAseq is a mess - and a method that merits vanishing asap. Hopefully all the bioinformatics efforts can be repurposed Ming "Tommy" Tang

ᒍOᕼᗩᑎ ᗪᑌᑕᕼEᑎE Elisabeth Bik nature.com/articles/d4158… Paywalled. My images from the article:

Very satisfying to see that 88% of you spotted the fake TEM image! Many noted it would've been trickier without a real image next to it to compare - unless you're a TEM specialist. With AI advancing fast, spotting fake images may soon become harder...

Non-specific #antibodies still plague #reproducibility in biomedical research. YCharOS tackles this by testing commercial antibodies in knockout cell lines—and sharing the data openly. Learn more in their online seminar: May 29, 2025 | 4pm–5pm CEST tinyurl.com/YCharOs-Seminar

Popular methods like UMAP & t-SNE are stochastic and distort data structure. Bonsai - a novel method - builds trees to relate high-dimensional objects, accounting for measurement noise. biorxiv.org/content/10.110…

Sicklinger & colleagues developed a new #ultrasound-guided method to induce #HeartAttacks in mice, allowing precise control & real-time monitoring without the need for invasive surgery. Learn more at ahajrnls.org/42R7ZGs @volkersmirko Junedh M. Amrute Rafael Kramann, MD PhD

Ryan Hill ᒍOᕼᗩᑎ ᗪᑌᑕᕼEᑎE Yes. Source is on GitHub. There is also a webserver at bonsai.unibas.ch where you can upload your data. Check ‘code and data availability ‘ section.

Ryan Hill ᒍOᕼᗩᑎ ᗪᑌᑕᕼEᑎE github.com/dhdegroot/Bons…

ᒍOᕼᗩᑎ ᗪᑌᑕᕼEᑎE github.com/dhdegroot/Bons…

🧵5 Top Free Alternatives to BioRender for Scientific Illustrations! These five websites offer free scientific illustrations for biologists. Great for presentations, research papers and other research communication needs. Save and share the post!

Your data is lying to you. Here’s how technical artifacts distort biology—and how to see the truth. 👇 1/ Beautiful t-SNE? Shiny heatmap? Look closer. Technical artifacts can fake whole cell types. Here’s where the ghosts hide.

The scientific literature is at risk of becoming flooded with papers that make misleading health claims. nature.com/articles/d4158…