This damn detector is going to give me an ulcer. Or cause me to quit my job. #fuuuuuuuuuck #scopemom

If you’re new to the field, consider applying to the @cshl cryoem course - fun and intensive two week, hands-on training on all aspects of single particle #cryoem

Want to join the cryo-EM team at Genentech? We're hiring! careers.gene.com/udlzLFe If you think you are, or know, someone who is a good match for this posting, please contact us!

Another great opportunity to join the Genentech #cryoem team!

Finally out! nature.com/articles/s4158…

Deadline coming up for applications to the #cryoem course this March. It's a great opportunity for novices to learn the basics of sample prep, microscope operation, and image processing. And it's always fun! Lander Lab Jennifer Cash CSHL Courses meetings.cshl.edu/courses.aspx?c…

Congratulations to FSU Cell & Molecular Biology Program student Nidhi Walia for earning a Student Research Achievement Award (aka poster prize) at the annual Biophysical Society meeting. Well done! (but I'll throw in some props to all the MOB Graduate Program at FSU students who attended!).

Alister Burt @MRC_LMB Genentech Congrats! I was hoping this will be an outcome. Excited to work with you later this year.

Point mutations in IMPDH2 which cause early-onset neurodevelopmental disorders disrupt enzyme regulation and filament structure biorxiv.org/cgi/content/sh…

Our latest work from Jensen Lab on cryo-ET of Legionella Dot/Icm T4SS is now available on biorxiv. biorxiv.org/content/10.110… Here are some key findings: 1/7

A set of visual experiments: applying Fourier transform to various plane-filling curves github.com/dmishin/fft-im…

Happy to finally share our publication on multiplexable, genetically-encoded barcodes for EM now out Nature Biotechnology. If you are interested in this technology, I am happy to discuss all its details (just DM me, I am also looking for opportunities to present these ideas in a talk).

SmartScope v0.9 collecting at a rate of 421 movies/h on R2/1, 7-shots per hole, very conservative 4.5um max beam-image shift. Setup time after the scope was aligned: 20 min. Fully automated from there. 😅Just need to improve the display of the targets at the medium mag now..

Nice to see a concise summary of Stefan Huber et all, as well as our own research on #gasvesicles, featured in NatureStructMolBiol. It's great to witness GVs garnering increased interest!

Am I the only one that thinks electron microscopes are just so damn ugly now? All you see is a box. Half the fun was seeing cables hanging and fumes from LN2 everywhere while imaging. All that is gone and its just so sterile now 🙄

Super fun project with Aoife Heaslip - twitterless Kelli worked with them on the #cryoem structure of Toxoplasma actin from. Beautiful functional characterization by Tom Sladewski. Now on bioRxiv biorxiv.org/cgi/content/sh…

Just published in NatureStructMolBiol: The @SchurLab uncovers the architecture of the #poxviruscore using a combination of #cryoEMmethods & molecular modeling. The key component: Core protein A10. Read more: bit.ly/4802GUn Co-first authors Julia Datler& Jesse Hansen Jesse Hansen

To #TeamTomo ❄️🔬: Do you also sometimes see strange filaments in your #cryoET data and don’t know what they are? 🤔 Try #FilamentID! 🪄🤓 Check out our new paper at Cell by @HugenerJannik and Jingwei Xu together with the Matos lab cell.com/cell/fulltext/… 🧵(1/5)

Pretty neat to see my structure posted on the Nobel prize page today 😄. Congrats to Institute for Protein Design and all those involved here :)

OK, I think I'm done here. Elmo has ruined this site. I joined to hear of exciting new science being done in the world but now my feed is nothing but politics and ads. New handle at the blue one: drmatthewcjohnson