Review: Prospects and limitations of NK cell adoptive therapy in clinical applications link.springer.com/article/10.100…

Extracellular vesicles (EVs) are tiny bubble-like structures released by cells that carry proteins, RNA, and other molecules to nearby or distant cells. SARS-CoV-2 viral persistence is one of the mechanisms thought to be causing #LongCOVID, yet until now it has been hard to

𝗠𝗲𝗰𝗵𝗮𝗻𝗶𝘀𝗺𝘀 𝗼𝗳 𝗔𝗰𝘁𝗶𝗼𝗻 𝗼𝗳 𝗧𝗲𝘀𝘁𝗼𝘀𝘁𝗲𝗿𝗼𝗻𝗲 Many of the benefits and some of the risks of testosterone treatment are mediated by the mechanisms through which testosterone acts. Testosterone has anabolic effects on muscle (panel A) and bone (panel B) and

Potentiation of mitochondrial function by mitoDREADD-Gs reverses pharmacological and neurodegenerative cognitive impairment in mice | Nature Neuroscience nature.com/articles/s4159…

Two new Science studies in mice reveals that food-induced anaphylaxis is driven by distinct immune pathways involving inflammatory lipids called leukotrienes. The findings point to the potential of the drug Zileuton to block this life-threatening response. 📄:

Testosterone: one of the most powerful hormone capable of driving anatomical, physiological, and metabolic changes in the body is made in your mitochondria Women and men make testosterone, but in men mitochondria in testes leydig cells can make very high levels

Online Now: Triglyceride-based lipotoxicity in the pathophysiology of chronic diseases dlvr.it/TMRbkr #trends #endocrinology #metabolism

New content online: Peripheral neuronal sensitization and neurovascular remodelling in osteoarthritis pain bit.ly/4oviR5u

A new Science Immunology study has uncovered how a nuclear cell cycle protein called BUB1 helps proteins resist radiotherapy. The findings could inform future approaches to enhance outcomes for cancer patients. scim.ag/4mBWsls

Why the Blood-Brain Barrier Weakens With Age Researchers have identified why the blood-brain barrier becomes more permeable with age, a change linked to early memory decline. The study revealed that two key proteins, N-cadherin and occludin, work together to maintain tight

Microglia regulate GABAergic neurogenesis in prenatal human brain through IGF1 | Nature nature.com/articles/s4158…

Migration of cell populations is a fundamental process in morphogenesis and disease. Researchers have identified a novel form of collective mesenchymal cell migration during chick gastrulation, where cells self-organise into a dynamic meshwork structure. elifesciences.org/articles/84749…

Scientists Just Used CRISPR to Completely Erase HIV from Human Cells — and the Cells Stayed Immune Forever After A team of experts at Temple University in Philadelphia has made a major leap in the fight against HIV by deploying CRISPR/Cas9—a precise DNA-cutting tool—to wipe out

Researchers in @SciSignal report that calcium channels in rodent hippocampal neurons are an important target in dopamine receptor signaling, hinting that these channels could be targeted to treat neuropsychiatric disorders. scim.ag/3KGCMze

Cracking the case: how did adenoviral vector vaccine such as the J&J's Covid induce very rare and potentially fatal clotting, bleeding? An elegant proof of molecular mimicry—genetic background + rogue antibodies nejm.org/doi/full/10.10… theatlantic.com/science/2026/0… Roxanne Khamsi

Fibroblasts as regulators of lung immunity, repair and fibrosis dlvr.it/TQwXhL

BREAKTHROUGH: Scientists just grew mini human spinal cords, then made them repair after injury. Scientists have shown that a regenerative therapy called “dancing molecules” can repair damage in lab grown human spinal cord organoids. Researchers created miniature human spinal

BREAKING: Case Western just discovered the hidden protein interaction driving Parkinson's They found alpha-synuclein attacks mitochondria (brain's power plants), cutting off energy. Then designed a drug that blocks this interaction Restored movement in animal models ⚡

What would it look like to see all ~13,000 proteins inside a single human cell at once? We share ProtiCelli — a generative model that makes this possible. Besides benchmarking, we demonstrate utility in many tasks. Preprint: bit.ly/3NY175q A thread 🧵👇