Darren Poole (@dpsynthchemist) 's Twitter Profile
Darren Poole

@dpsynthchemist

Team leader @GSK high-throughput chemistry | New methodologies and enabling technologies for drug discovery | DPhil @DonohoeGroup | F1 Obsessive | Views my own!

ID: 1391820335771791369

calendar_today10-05-2021 18:20:13

609 Tweet

579 Followers

446 Following

J Org Chem/Org Lett (@joc_ol) 's Twitter Profile Photo

Check out “Utilization of HTE and ChemBeads Toward the Development of an Aryl Bromide and Benzyl Bromide Photoredox Cross-Electrophile Coupling.” Synthesis of diarylmethanes by GSK US (Martin Rauch, Noel, @tessacolameta, James Phelan, Ann Rowley) pubs.acs.org/doi/10.1021/ac…

Check out “Utilization of HTE and ChemBeads Toward the Development of an Aryl Bromide and Benzyl Bromide Photoredox Cross-Electrophile Coupling.” Synthesis of diarylmethanes by <a href="/GSKUS/">GSK US</a> (<a href="/Marty_Rauch/">Martin Rauch</a>, <a href="/ngcercizi/">Noel</a>, @tessacolameta, <a href="/jpatphelan/">James Phelan</a>, <a href="/AnnRowley_77/">Ann Rowley</a>) pubs.acs.org/doi/10.1021/ac…
Synthesis Workshop (@matthewhorwitz1) 's Twitter Profile Photo

Today on Synthesis Workshop, Joe Anderson (GSK, University of Strathclyde) joins us to share his work on the synthesis of bridge-substituted BCPs! Link: youtu.be/VKTPx1gAXaU Key paper: Chemistry 2024, 30, e202304070. doi.org/10.1002/chem.2…

Today on Synthesis Workshop, Joe Anderson (GSK, University of Strathclyde) joins us to share his work on the synthesis of bridge-substituted BCPs!

Link:
youtu.be/VKTPx1gAXaU

Key paper:
<a href="/ChemEurJ/">Chemistry</a> 2024, 30, e202304070. doi.org/10.1002/chem.2…
Joe Anderson (@anderson_j_m) 's Twitter Profile Photo

Excited to see this video released which covers some of the work from my PhD GSK and Chemistry - University of Strathclyde. Thank you Synthesis Workshop for the opportunity to present, and to my supervisors/co-authors Darren Poole, Nick Measom, Prof. John Murphy, and Gemma for their support.

Stahl Lab (@stahl_lab) 's Twitter Profile Photo

Asmaul and Tianxiao take us one step closer to eliminating peroxides and other undesirable oxidants in organic chemistry. Thanks to Darren Poole GSK for med chem contributions! pubs.acs.org/doi/10.1021/ja…

Darren Poole (@dpsynthchemist) 's Twitter Profile Photo

Absolutely delighted to see this paper with Asmaul, Tianxiao and Shannon Stahl Lab appearing in J. Am. Chem. Soc.! Thrilled to have been a part of this very enjoyable collaboration to selectively oxidise sulfur to sulfoxides electrochemically ⚡️

Nikki G (@nikkig_conshy) 's Twitter Profile Photo

I love this work from Asmaul and Tianxiao in the Stahl Lab . Sulfoxide synthesis without overoxidation? ✅. Simplest oxidant? ✅. Darren Poole and I think the community will find this useful so check it out!

Steve Fletcher (@spfletcher) 's Twitter Profile Photo

Steve (not on twitter) et al’s study on Rh(I)-Catalyzed Regio- and Enantioselective Ring Opening of Vinyl Cyclopropanes | Journal of the American Chemical Society pubs.acs.org/doi/10.1021/ja…

EFMC (@euromedchem) 's Twitter Profile Photo

📣Starting Session 3: “Novel methodologies in photo- and electrochemistry” in Room Pantheon chaired by Dr Lisa Candish, with a lecture from Ms Gemma Cook of GSK on "The Application of Photochemistry to Accelerate the Discovery of Drug Candidates at GSK" #EFMCISMC24 #MedChem

📣Starting Session 3: “Novel methodologies in photo- and electrochemistry” in Room Pantheon chaired by Dr Lisa Candish, with a lecture from Ms Gemma Cook of <a href="/GSK/">GSK</a> on "The Application of Photochemistry to Accelerate the Discovery of Drug Candidates at GSK" #EFMCISMC24 #MedChem
EFMC (@euromedchem) 's Twitter Profile Photo

📣 Session 12 – Dr. Pilar MANZANO-CHINCHON from GSK is now on the stage for the talk titled “Structure-Guided Design and Synthesis of a Pyridazinone Series of Trypanosoma Cruzi Proteasome Inhibitors”. Keep following us! 🔬💡 #EFMCISMC24 #MedChem

📣 Session 12 – Dr. Pilar MANZANO-CHINCHON from <a href="/GSK/">GSK</a> is now on the stage for the talk titled “Structure-Guided Design and Synthesis of a Pyridazinone Series of Trypanosoma Cruzi Proteasome Inhibitors”. Keep following us! 🔬💡
#EFMCISMC24 #MedChem
Strathclyde-GSK MPhil & PhD Programmes (@strath_gsk_phd) 's Twitter Profile Photo

We are pleased to open our recruitment for our collaborative GSK/Chemistry - University of Strathclyde PhD Studentships starting Oct 2025 in the areas of Synthetic and Medicinal Chemistry. Students will be based at GSK, Stevenage. Full details below and at: strath.ac.uk/science/chemis… Deadline: 06/01/2025.

We are pleased to open our recruitment for our collaborative <a href="/GSK/">GSK</a>/<a href="/StrathChem/">Chemistry - University of Strathclyde</a> PhD Studentships starting Oct 2025 in the areas of Synthetic and Medicinal Chemistry.  Students will be based at GSK, Stevenage.  Full details below and at: strath.ac.uk/science/chemis…
Deadline: 06/01/2025.
Kevin Lam (@klchemistry) 's Twitter Profile Photo

"Farewell, ☠️KCN!" Meet #eCyanation: the safer, scalable way to perform nucleophilic & electrophilic cyanations! Incredible work by Valerio Morlacci &⚡ElectraTeam⚡at Uni of Greenwich! Transforming #GreenChemistry!#RealTimeChem #OpenAccess DualFlowProjectEU pubs.acs.org/doi/10.1021/ja…

"Farewell, ☠️KCN!" Meet #eCyanation: the safer, scalable way to perform nucleophilic &amp; electrophilic cyanations! Incredible work by <a href="/MorlacciValerio/">Valerio Morlacci</a> &amp;⚡ElectraTeam⚡at <a href="/UniofGreenwich/">Uni of Greenwich</a>! Transforming #GreenChemistry!#RealTimeChem #OpenAccess <a href="/DualFlowProject/">DualFlowProjectEU</a> pubs.acs.org/doi/10.1021/ja…
Angewandte Chemie (@angew_chem) 's Twitter Profile Photo

Redox-Tunable #RingExpansion Enabled By A Single-Component Electrophilic Nitrogen Atom Synthon (Mark D. Levin and co-workers) Mark Levin Levin Group Patrick Kelly UChicago Chemistry #openaccess onlinelibrary.wiley.com/doi/10.1002/an…

Dr Sam Rowe (@sammrowe) 's Twitter Profile Photo

Congratulations to Harry_Wilders and the team for getting this exciting ‘Direct-to-Biology’ work out there! We generate cysteine-targeting chloroactemide reactive fragments and screen them without purification to optimise inhibitors of SARS MPro. onlinelibrary.wiley.com/doi/10.1002/an…

Kevin Lam (@klchemistry) 's Twitter Profile Photo

🎄 Christmas surprise by Cyrille Kiaku, Darren Poole & team Uni of Greenwich @FESGreenwich GSK ⚡ eEtherification ⚡: Rapid, efficient, and versatile assembly of sterically hindered ethers from readily available alcohols. #RealTimeChem #OrganoeChem pubs.acs.org/doi/abs/10.102…

🎄 Christmas surprise by <a href="/CK_echem/">Cyrille Kiaku</a>, <a href="/DPSynthChemist/">Darren Poole</a> &amp; team
<a href="/UniofGreenwich/">Uni of Greenwich</a> @FESGreenwich <a href="/GSK/">GSK</a>
⚡ eEtherification ⚡: Rapid, efficient, and versatile assembly of sterically hindered ethers from readily available alcohols.

 #RealTimeChem #OrganoeChem

pubs.acs.org/doi/abs/10.102…
J Org Chem/Org Lett (@joc_ol) 's Twitter Profile Photo

New in Organic Letters! ⚡ eEtherification: A mild, versatile electrochemical method to synthesise sterically hindered ethers from common alcohols. 🎄 By @KLChemistry & team Uni of Greenwich GSK #OrgLett go.acs.org/c1v