Our paper with @JuleneMadMar and the Siksnys Lab "The energy landscape for R-loop formation by the CRISPR–Cas Cascade complex" is out at NatureStructMolBiol. If you're into in CRISPR or high-speed single-molecule twist and torque measurements, give it a read! doi.org/10.1038/s41594…

#CRISPR-Genscheren greifen manchmal auch daneben. Um besser zu verstehen, was dabei passiert, haben Forscher:innen der #UniLeipzig um Dominik J Kauert den Prozess auf Nanoebene sichtbar gemacht: uni-leipzig.de/newsdetail/art… #Nanotechnologie

#CRISPR genetic scissors sometimes miss the mark. To better understand what happens in the process, researchers at #UniLeipzig led by Dominik J Kauert visualised the process at the nanoscale: uni-leipzig.de/en/newsdetail/… #nanotechnology

I can relate 🫣

Very grateful that our work is covered on NatureStructMolBiol. Once again, I want to thank everyone involved with this publication.

Are you wondering how to do #singlemolecule #biophysics experiments? Together with my Vrije Universiteit Amsterdam (inactief) colleagues Iddo Heller and Erwin Peterman, we edited a book for single-molecule biophysics protocols and methods with the best people in the field! link.springer.com/book/10.1007/9…